SB 431542

目录号: A10826

TGF-beta/Smad 抑制剂

SB 431542

SB 431542 Chemical Structure

CAS NO. 301836-41-9

SB 431542是转化生长因子-β超家族I型激活素受体样激酶(ALK)受体ALK4,ALK5和ALK7的有效抑制剂。

库存: 现货

规格 价格 数量
10 mg
¥ 800.00
25 mg
¥ 1,600.00
50 mg
¥ 3,000.00
100 mg
¥ 5,600.00
10mM * 1mL in DMSO
¥ 800.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

SB 431542是转化生长因子-β超家族I型激活素受体样激酶(ALK)受体ALK4,ALK5和ALK7的有效抑制剂。
靶点信息
ALK4 (Cell-free assay) ALK7 (Cell-free assay) ALK5 (Cell-free assay)
N/A94 nM
In vitro (25°C) DMSO 75 mg/mL (195.11 mM)
Water Insoluble
Ethanol 3 mg/mL (7.8 mM)
In vivo 2% DMSO+30% PEG 300+ddH2O 4 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.01 mL 130.07 mL 260.15 mL
0.5 mM 5.2 mL 26.01 mL 52.03 mL
1 mM 2.6 mL 13.01 mL 26.01 mL
5 mM 0.52 mL 2.6 mL 5.2 mL

*The above data is based on the productmolecular weight 384.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10826
作用机制 Inhibitor (抑制剂)
M. Wt 384.4
Formula C22H16N4O3
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 301836-41-9
Synonyms SB-431542, SB431542
SMILES C1OC2=C(O1)C=C(C=C2)C3=C(NC(=N3)C4=CC=C(C=C4)C(=O)N)C5=CC=CC=N5

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