SGI-7079

目录号: A15864

Axl 抑制剂

SGI-7079

SGI-7079 Chemical Structure

CAS NO. 1239875-86-5

SGI-7079是一种新型的选择性Axl抑制剂,以剂量依赖的方式抑制肿瘤的生长,并且是克服EGFR抑制剂耐药性的潜在治疗靶标。

库存: 现货

规格 价格 数量
5 mg
¥ 800.00
10 mg
¥ 1,400.00
25 mg
¥ 2,800.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

SGI-7079是一种新型的选择性Axl抑制剂,以剂量依赖的方式抑制肿瘤的生长,并且是克服EGFR抑制剂耐药性的潜在治疗靶标。
Targets
Target Value
Met
Mer
YES
RET
FLT3
AxlIC50: 58nM
In vitro DMSO 77 mg/mL (169.03 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.95 mL 109.76 mL 219.52 mL
0.5 mM 4.39 mL 21.95 mL 43.9 mL
1 mM 2.2 mL 10.98 mL 21.95 mL
5 mM 0.44 mL 2.2 mL 4.39 mL

*The above data is based on the productmolecular weight 455.53. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A15864
作用机制 Inhibitor (抑制剂)
M. Wt 455.53
Formula C26H26FN7
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1239875-86-5
Synonyms SGI7079, SGI 7079
SMILES N#CCC1=CC=CC(C2=C3C(NC=C3C)=NC(NC4=CC=C(N5CCN(C)CC5)C(F)=C4)=N2)=C1

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