(Z)-SMI-4a

Name: (Z)-SMI-4a
SKU: A11945

目录号: A11945

Pim 抑制剂

Product Citations (1)

(Z)-SMI-4a Chemical Structure

CAS NO. 327033-36-3

SIM-4a是一种Pim激酶抑制剂，可通过激活AMPK来阻断mTORC1的活性。通常对Pim-2有效，不会显着抑制任何其他丝氨酸/苏氨酸或酪氨酸激酶。

库存：现货

规格	价格	数量
10 mg	￥ 650.00
25 mg	￥ 1,400.00
50 mg	￥ 2,600.00
100 mg	￥ 5,000.00

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生物活性

SIM-4a是一种Pim激酶抑制剂，可通过激活AMPK来阻断mTORC1的活性。通常对Pim-2有效，不会显着抑制任何其他丝氨酸/苏氨酸或酪氨酸激酶。

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	36.6 mL	183.02 mL	366.03 mL
0.5 mM	7.32 mL	36.6 mL	73.21 mL
1 mM	3.66 mL	18.3 mL	36.6 mL
5 mM	0.73 mL	3.66 mL	7.32 mL

*The above data is based on the productmolecular weight 273.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A11945
作用机制	Inhibitor (抑制剂)
M. Wt	273.2
Formula	C11H6F3NO2S
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	327033-36-3
Synonyms	SMI4a
SMILES	O=C(NC/1=O)SC1=C/C2=CC=CC(C(F)(F)F)=C2