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￥ 0.00 “soluble guanylyl cyclase sgc”的搜索结果
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SGC 0946
Catalog No. A12941 -
Glutaminyl Cyclase Inhibitor 1
Catalog No. A19723 glutaminyl cyclase inhibitorGlutaminyl Cyclase Inhibitor 1 is a glutaminyl cyclase inhibitor with an IC50 of 0.5 μM. 了解更多 -
Glutaminyl Cyclase Inhibitor 2
Catalog No. A19713 glutaminyl cyclase inhibitorGlutaminyl Cyclase Inhibitor 2 is a glutaminyl cyclase inhibitor with an IC50 of 1.23 μM. 了解更多 -
Glutaminyl Cyclase Inhibitor 3
Catalog No. A20399 GC inhibitorGlutaminyl Cyclase Inhibitor 3 (compound 212 ), a designed anti-Alzheimer??s compound, is a potent human Glutaminyl Cyclase (GC) inhibitor, with an IC50 of 4.5 nM. 了解更多 -
Olinciguat
Catalog No. A13670 guanylate cyclase (sGC) stimulatorOlinciguat (IW-1701) is an oral guanylate cyclase (sGC) stimulator with concentration-dependent stimulation of sGC in purified rat and human enzyme assays and a whole cell assay. 了解更多 -
Praliciguat
Catalog No. A19315 guanylate cyclase stimulatorPraliciguat (IW-1973) is a potent and orally active soluble guanylate cyclase stimulator, enhances NO signaling, acts as a vasodilator. Praliciguat (IW-1973) stimulates sGC in HEK-293 cells with an EC50 of 197 nM. 了解更多 -
Cinaciguat
Catalog No. A21283 sGC activatorCinaciguat is an activator of guanylate cyclase (sGC), and used for acute decompensated heart failure. 了解更多 -
Runcaciguat
Catalog No. A20200 soluble guanylate cyclase stimulatorRuncaciguat is an orally active stimulator of soluble guanylate cyclase, and is used in the research of cardiovascular and renal diseases combined with selective partial adenosine A1 receptor agonists. 了解更多 -
Nelociguat
Catalog No. A20591 guanylate cyclase stimulatorNelociguat (BAY60-4552) is a nitric oxide sensitive soluble guanylate cyclase stimulator. 了解更多 -
Vericiguat
Catalog No. A21031 guanylate cyclase stimulatorVericiguat (BAY1021189) is a potent, orally available and soluble guanylate cyclase stimulator. 了解更多 -
Cinaciguat hydrochloride
Catalog No. A21838 guanylate cyclase (GC) activatorCinaciguat hydrochloride is a potent soluble guanylate cyclase (GC) activator with EC50 of 15 nM in platelets. 了解更多 -
BAY 41-2272
Catalog No. A15891 -
YC-1 (Lificiguat)
Catalog No. A12402 -
Riociguat (BAY 63-2521)
Catalog No. A11549 -
CB-7921220
Catalog No. A19934 -
(4-Acetamidocyclohexyl) nitrate
Catalog No. A13355 guanylate cyclase activator(4-Acetamidocyclohexyl) nitrate (BM121307) is a guanylate cyclase activator that was in phase I development for the treatment of ischaemic heart disorders. The research has been discontinued. 了解更多 -
Cy3 NHS ester
Catalog No. A12635 Cy3 NHS (Cyanine3 NHS ester) is a water-soluble and yellow emitting fluorescent dye for labeling amino-groups in biomolecules. Used to label soluble proteins, peptides, and oligonucleotides/DNA. 了解更多 -
THPP-1
Catalog No. A22650 PDE10A inhibitorTHPP-1, a SGC chemical probe, is a potent and orally bioavailable phosphodiesterase 10A (PDE10A) inhibitor, with Ki values of 1 nM and 1.3 nM for human and rat PDE10A, respectively. THPP-1 has excellent pharmacokinetic properties in preclinical species. 了解更多 -
BAY-678 racemate
Catalog No. A19564 HNE inhibitorBAY-678 racemate is a racemate of BAY-678. BAY-678 is an orally bioavailable, highly potent, selective and cell-permeable inhibitor of human neutrophil elastase (HNE), with an IC50 of 20 nM. BAY-678 is also nominated as a chemical probe to the public via the Structural Genomics Consortium (SGC). 了解更多 -
Plecanatide acetate
Catalog No. A21393 GC-C receptor agonistPlecanatide acetate is a guanylate cyclase-C (GC-C) receptor agonist, with an EC50 of 190 nM in T84 cells. Plecanatide acetate shows anti-inflammatory activity in models of murine colitis. 了解更多 -
SQ22536
Catalog No. A16116 -
DNQX Disodium
Catalog No. A22623 non-NMDA receptor antagonistDNQX Disodium is a water-soluble form of selective non-NMDA receptor antagonist DNQX. 了解更多 -
1-Cyclohexyl-3-dodecyl urea
Catalog No. A22690 sEH inhibitor1-Cyclohexyl-3-dodecyl urea (CDU; N-Cyclohexyl-N-dodecyl urea; NCND) is a highly selective soluble epoxide hydrolase (sEH) inhibitor. 了解更多 -
SBI-0640756
Catalog No. A20730 eIF4G1 inhibitorSBI-0640756 (SBI-756) is a water soluble inhibitor of eIF4G1 and disrupts the eIF4F complex. 了解更多 -
GSK2256294A
Catalog No. A20696 recombinant human sEH inhibitorGSK2256294A is a potent, reversible, tight binding inhibitor of isolated recombinant human sEH (soluble epoxide hydrolase) (IC50 = 27 pM; t1/2 = 121 min) and displays potent inhibition against the rat (IC50 = 61 pM) and murine (IC50 = 189 pM) orthologs of sEH. 了解更多 -
Oxaquin
Catalog No. A20486 Oxaquin (MCB-3837) is a water-soluble, injectable prodrug that is rapidly converted to the active sub-stance MCB3681 in vivo following intravenous (i.v.) administration, active against Gram-positive bacterial species. Oxaquin (MCB-3837) itself has no antimicrobial effects. 了解更多 -
Rilmazafone
Catalog No. A20222 Rilmazafone is a water-soluble benzodiazepine prodrug that acts as a sedative and hypnotic neuropsychiatric agent. 了解更多 -
Moniliformin sodium salt
Catalog No. A19635 Moniliformin sodium salt is a potent, water-soluble mycotoxin isolate from Fusarium moniliforme. 了解更多 -
YHO-13351 free base
Catalog No. A21568 BCRP inhibitorYHO-13351 (free base) is the water-soluble prodrug of YHO-13177, which is a potent and specific inhibitor of BCRP. 了解更多 -
Retaspimycin
Catalog No. A15221 Hsp90 inhibitorRetaspimycin is a potent and water-soluble inhibitor of Hsp90, with EC50s of 119 nM for both Hsp90 and Grp9. 了解更多
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