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SR 144528是一种选择性的外周大麻素受体反向激动剂，对大鼠脾脏和人重组CB2受体的Ki值为0.6 nM，对大鼠脑和人重组CB1受体的Ki值为400 nM。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.01 mL | 105.03 mL | 210.06 mL |
| 0.5 mM | 4.2 mL | 21.01 mL | 42.01 mL |
| 1 mM | 2.1 mL | 10.5 mL | 21.01 mL |
| 5 mM | 0.42 mL | 2.1 mL | 4.2 mL |
*The above data is based on the productmolecular weight 476.05. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A12376 |
|---|---|
| 作用机制 | Agonist (激动剂) |
| M. Wt | 476.05 |
| Formula | C29H34ClN3O |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 192703-06-3 |
| Synonyms | SR144528, SR-144528 |
| SMILES | CC1=CC=C(C=C1)CN2C(=CC(=N2)C(=O)N[C@H]3[C@]4(CC[C@H](C4)C3(C)C)C)C5=CC(=C(C=C5)Cl)C |
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