SU14813

目录号: A11557

VEGFR 抑制剂

SU14813

SU14813 Chemical Structure

CAS NO. 627908-92-3

SU14813是一种口服多靶向酪氨酸激酶抑制剂(TKI),靶向血管内皮生长因子受体(VEGFR)、血小板衍生生长因子受体(PDGFR)、KIT和fms样酪氨酸激酶3 (FLT-3),抑制 VEGFR2,VEGFR1,PDGFRβ and KIT 的 IC50 值分别为50,2,4,15 nM。

库存: 缺货

规格 价格
5 mg
¥ 750.00
10 mg
¥ 1,050.00
25 mg
¥ 1,900.00
50 mg
¥ 2,800.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

SU14813是一种口服多靶向酪氨酸激酶抑制剂(TKI),靶向血管内皮生长因子受体(VEGFR)、血小板衍生生长因子受体(PDGFR)、KIT和fms样酪氨酸激酶3 (FLT-3),抑制 VEGFR2,VEGFR1,PDGFRβ and KIT 的 IC50 值分别为50,2,4,15 nM。
In vitro DMSO 79 mg/mL (178.53 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.6 mL 113 mL 226 mL
0.5 mM 4.52 mL 22.6 mL 45.2 mL
1 mM 2.26 mL 11.3 mL 22.6 mL
5 mM 0.45 mL 2.26 mL 4.52 mL

*The above data is based on the productmolecular weight 442.48. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11557
作用机制 Inhibitor (抑制剂)
M. Wt 442.48
Formula C23H27FN4O4
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 627908-92-3
Synonyms SU14813; SU 14813; SU-14813
SMILES CC1=C(NC(=C1C(=O)NC[C@@H](CN2CCOCC2)O)C)/C=C\3/C4=C(C=CC(=C4)F)NC3=O

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