SW033291

目录号: A15798

15-PGDH enzyme 抑制剂

SW033291

SW033291 Chemical Structure

CAS NO. 459147-39-8

SW033291是15-PGDH的小分子抑制剂(Ki = 0.1 nM),可增加骨髓和其他组织中前列腺素PGE2的水平。

库存: 现货

规格 价格 数量
5 mg
¥ 750.00
10 mg
¥ 1,200.00
25 mg
¥ 2,700.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

SW033291是15-PGDH的小分子抑制剂(Ki = 0.1 nM),可增加骨髓和其他组织中前列腺素PGE2的水平。
靶点信息
15-PGDH 15-PGDH
0.1 nM(Ki)1.5 nM
In vitro (25°C) DMSO 77 mg/mL (186.62 mM)
Water Insoluble
Ethanol Warmed: 30 mg/mL (72.7 mM)
In vivo 5% DMSO+corn oil 9 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.24 mL 121.19 mL 242.37 mL
0.5 mM 4.85 mL 24.24 mL 48.47 mL
1 mM 2.42 mL 12.12 mL 24.24 mL
5 mM 0.48 mL 2.42 mL 4.85 mL

*The above data is based on the productmolecular weight 412.59. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A15798
作用机制 Inhibitor (抑制剂)
M. Wt 412.59
Formula C21H20N2OS3
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 459147-39-8
Synonyms SW 033291, SW-033291
SMILES NC1=C(S(CCCC)=O)SC2=NC(C3=CC=CS3)=CC(C4=CC=CC=C4)=C21

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