T0901317

Name: T0901317
SKU: A12652

目录号: A12652

LXR/FXR 激动剂

Product Citations (1)

T0901317 Chemical Structure

CAS NO. 293754-55-9

T0901317是有效的，高亲和力的肝X受体（LXR）激动剂（EC50~50 nM，LXR-β和LXR-β的Kd值分别为7和22 nM）。

库存：现货

规格	价格	数量
10 mg	￥ 500.00
25 mg	￥ 700.00
50 mg	￥ 1,000.00
100 mg	￥ 1,500.00
10mM * 1mL in DMSO	￥ 500.00

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生物活性

T0901317是有效的，高亲和力的肝X受体（LXR）激动剂（EC50~50 nM，LXR-β和LXR-β的Kd值分别为7和22 nM）。

靶点信息

LXR	FXR
50 nM(EC50)	5 μM(EC50)

溶解度 *

In vitro (25°C)	DMSO	88 mg/mL (182.82 mM)
	Water	Insoluble
	Ethanol	88 mg/mL (182.82 mM)
In vivo	2% DMSO+35% PEG 300+5% Tween 80+ddH2O	5 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	20.78 mL	103.88 mL	207.76 mL
0.5 mM	4.16 mL	20.78 mL	41.55 mL
1 mM	2.08 mL	10.39 mL	20.78 mL
5 mM	0.42 mL	2.08 mL	4.16 mL

*The above data is based on the productmolecular weight 481.33. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A12652
作用机制	Agonist (激动剂)
M. Wt	481.33
Formula	C17H12F9NO3S
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	293754-55-9
SMILES	C1=CC=C(C=C1)S(=O)(=O)N(CC(F)(F)F)C2=CC=C(C=C2)C(C(F)(F)F)(C(F)(F)F)O