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TAK-259是一种新型的，选择性的，口服活性的α1D肾上腺素受体拮抗剂（α1D，Ki = 1.1 nM），具有抗尿频效应并减少人类以太相关基因（hERG）的责任。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 24.35 mL | 121.74 mL | 243.49 mL |
| 0.5 mM | 4.87 mL | 24.35 mL | 48.7 mL |
| 1 mM | 2.43 mL | 12.17 mL | 24.35 mL |
| 5 mM | 0.49 mL | 2.43 mL | 4.87 mL |
*The above data is based on the productmolecular weight 410.7. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A16186 |
|---|---|
| 作用机制 | Antagonist (拮抗剂) |
| M. Wt | 410.7 |
| Formula | C14H14Cl3N3O3S |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1192347-42-4 |
| Synonyms | TAK259, TAK-259 |
| SMILES | O=C(C1=CC(Cl)=CN(CC2=CC(Cl)=CC=C2S(=O)(C)=O)C1=N)N.[H]Cl |
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