Telaprevir (VX-950)

目录号: A10902

HCV NS3-4A protease 抑制剂

Telaprevir (VX-950)

Telaprevir (VX-950) Chemical Structure

CAS NO. 402957-28-2

Telaprevir (VX-950)被称为蛋白酶抑制剂,可抑制丙型肝炎病毒NS3.4A丝氨酸蛋白酶。

库存: 现货

规格 价格 数量
2 mg
¥ 600.00
5 mg
¥ 900.00
10 mg
¥ 1,600.00
25 mg
¥ 3,200.00
10mM * 1mL in DMSO
¥ 1,800.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Telaprevir (VX-950)被称为蛋白酶抑制剂,可抑制丙型肝炎病毒NS3.4A丝氨酸蛋白酶。
靶点信息
HCV NS3-4A serine protease
0.35 μM
In vitro (25°C) DMSO 131 mg/mL (192.69 mM)
Water Insoluble
Ethanol Insoluble
In vivo 30% PEG400+0.5% Tween80+5% propylene glycol 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 14.71 mL 73.54 mL 147.08 mL
0.5 mM 2.94 mL 14.71 mL 29.42 mL
1 mM 1.47 mL 7.35 mL 14.71 mL
5 mM 0.29 mL 1.47 mL 2.94 mL

*The above data is based on the productmolecular weight 679.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10902
作用机制 Inhibitor (抑制剂)
M. Wt 679.9
Formula C36H53N7O6
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 402957-28-2
Synonyms VX950, Incivek, Incivo
SMILES CCC[C@@H](C(=O)C(=O)NC1CC1)NC(=O)[C@@H]2[C@H]3CCC[C@H]3CN2C(=O)[C@H](C(C)(C)C)NC(=O)[C@H](C4CCCCC4)NC(=O)C5=NC=CN=C5

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