Telatinib (BAY 57-9352)

目录号: A10903

VEGFR-2 抑制剂

Telatinib (BAY 57-9352)

Telatinib (BAY 57-9352) Chemical Structure

CAS NO. 332012-40-5

Telatinib (BAY 57-9352)是一种口服的血管内皮生长因子受体2和3(VEGFR2/3)和血小板衍生的生长因子受体β酪氨酸激酶的小分子抑制剂,IC50分别为6 nM/4 nM,1 nM和15 nM。

库存: 现货

规格 价格 数量
5 mg
¥ 900.00
10 mg
¥ 1,600.00
50 mg
¥ 4,500.00
100 mg
¥ 7,500.00
10mM * 1mL in DMSO
¥ 1,330.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Telatinib (BAY 57-9352)是一种口服的血管内皮生长因子受体2和3(VEGFR2/3)和血小板衍生的生长因子受体β酪氨酸激酶的小分子抑制剂,IC50分别为6 nM/4 nM,1 nM和15 nM。
靶点信息
c-Kit VEGFR3 VEGFR2 PDGFRα
1 nM4 nM6 nM15 nM
In vitro DMSO 71 mg/mL (173.24 mM)
Water Insoluble
Ethanol 1 mg/mL (2.44 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.4 mL 122.01 mL 244.02 mL
0.5 mM 4.88 mL 24.4 mL 48.8 mL
1 mM 2.44 mL 12.2 mL 24.4 mL
5 mM 0.49 mL 2.44 mL 4.88 mL

*The above data is based on the productmolecular weight 409.8 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10903
作用机制 Inhibitor (抑制剂)
M. Wt 409.8
Formula C20H16ClN5O3
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 332012-40-5
Synonyms BAY57-9352
SMILES CNC(=O)C1=NC=CC(=C1)COC2=NN=C(C3=C2OC=C3)NC4=CC=C(C=C4)Cl

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