Tenovin-6

目录号: A12305

p53 activator

Tenovin-6

Tenovin-6 Chemical Structure

CAS NO. 1011557-82-6

Tenovin-6是tenovin-1的类似物。Tenovin-6在体外抑制纯化的人SIRT1、SIRT2和SIRT3的蛋白脱乙酰酶活性,IC50值分别为21、10和67 uM。

库存: 现货

规格 价格 数量
5 mg
¥ 700.00
10 mg
¥ 900.00
25 mg
¥ 1,600.00
10mM * 1mL in DMSO
¥ 500.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Tenovin-6是tenovin-1的类似物。Tenovin-6在体外抑制纯化的人SIRT1、SIRT2和SIRT3的蛋白脱乙酰酶活性,IC50值分别为21、10和67 uM。
靶点信息
p53 SIRT2 SIRT1 SIRT3
N/A10 μM21 μM67 μM
In vitro DMSO 87 mg/mL (191.36 mM)
Water Warmed: 87 mg/mL (191.36 mM)
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22 mL 109.99 mL 219.97 mL
0.5 mM 4.4 mL 22 mL 43.99 mL
1 mM 2.2 mL 11 mL 22 mL
5 mM 0.44 mL 2.2 mL 4.4 mL

*The above data is based on the productmolecular weight 454.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A12305
作用机制 Activator (激活剂)
M. Wt 454.6
Formula C25H34N4O2S
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1011557-82-6
Synonyms Tenovin6, Tenovin 6
SMILES CC(C)(C)C1=CC=C(C=C1)C(=O)NC(=S)NC2=CC=C(C=C2)NC(=O)CCCCN(C)C

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