TH287

目录号: A15536

MTH1 抑制剂

TH287

TH287 Chemical Structure

CAS NO. 1609960-30-6

TH287是一种有效的MTH1(NUDT1)抑制剂,IC50值为0.8 nM,对MTH2,NUDT5,NUDT12,NUDT14和NUDT16的效力较低。

库存: 现货

规格 价格 数量
10 mg
¥ 900.00
25 mg
¥ 2,500.00
50 mg
¥ 4,800.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

TH287是一种有效的MTH1(NUDT1)抑制剂,IC50值为0.8 nM,对MTH2,NUDT5,NUDT12,NUDT14和NUDT16的效力较低。
靶点信息
MTH1 (NUDT1)
0.8 nM
In vitro DMSO 48 mg/mL (178.35 mM)
Water Insoluble
Ethanol Warmed: 9 mg/mL (33.44 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 37.16 mL 185.78 mL 371.57 mL
0.5 mM 7.43 mL 37.16 mL 74.31 mL
1 mM 3.72 mL 18.58 mL 37.16 mL
5 mM 0.74 mL 3.72 mL 7.43 mL

*The above data is based on the productmolecular weight 269.13. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A15536
作用机制 Inhibitor (抑制剂)
M. Wt 269.13
Formula C11H10Cl2N4
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1609960-30-6
Synonyms TH-287, TH 287
SMILES CNC1=NC(=NC(=C1)C2=C(C(=CC=C2)Cl)Cl)N

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