Thiostrepton

目录号: A12890

natural cyclic oligopeptide antibiotic

Thiostrepton

Thiostrepton Chemical Structure

CAS NO. 1393-48-2

Thiostrepton抑制细菌蛋白质合成的抗生素。通过GTPase延长因子G(EF-G),EF-TU(GTP)催化的aa-tRNA传递和起始因子2(IF-2)的活性来抑制mRNA-tRNA易位。抗肿瘤剂;通过下调FOXM1表达来诱导乳腺癌细胞的细胞周期停滞和凋亡。

库存: 现货

规格 价格 数量
100 mg
¥ 600.00
250 mg
¥ 1,200.00
500 mg
¥ 2,000.00
1000 mg
¥ 3,500.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Thiostrepton抑制细菌蛋白质合成的抗生素。通过GTPase延长因子G(EF-G),EF-TU(GTP)催化的aa-tRNA传递和起始因子2(IF-2)的活性来抑制mRNA-tRNA易位。抗肿瘤剂;通过下调FOXM1表达来诱导乳腺癌细胞的细胞周期停滞和凋亡。
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 6.01 mL 30.03 mL 60.06 mL
0.5 mM 1.2 mL 6.01 mL 12.01 mL
1 mM 0.6 mL 3 mL 6.01 mL
5 mM 0.12 mL 0.6 mL 1.2 mL

*The above data is based on the productmolecular weight 1664.89. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A12890
M. Wt 1664.89
Formula C72H85N19O18S5
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1393-48-2
Synonyms a-8506
SMILES CC[C@H](C)[C@@H]1C(=O)N[C@H](C(=O)NC(=C)C(=O)N[C@H](C(=O)N[C@]23CCC(=N[C@@H]2C4=CSC(=N4)[C@H]([C@H](OC(=O)C5=NC6=C(C=CC([C@@H]6O)N1)C(=C5)[C@H](C)O)C)NC(=O)C7=CSC(=N7)[C@@H](NC(=O)C8CSC(=N8)/C(=C/C)/NC(=O)[C@@H](NC(=O)C9=CSC3=N9)[C@@H](C)O)[C@@](C)([C@@H]

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