TRAM-34

Name: TRAM-34
SKU: A12783

目录号: A12783

Potassium Channel Blocker

Product Citations (2)

TRAM-34 Chemical Structure

CAS NO. 289905-88-0

TRAM-34是中等电导Ca2+激活的K+通道（KCa3.1）（Kd = 20 nM）的高度选择性阻滞剂。在KV，BKCa，KCa2，Na+，CRAC和Cl-通道上具有200-1500倍的选择性。抑制有丝分裂刺激对淋巴细胞的激活。

库存：现货

规格	价格	数量
10 mg	￥ 450.00
25 mg	￥ 900.00
50 mg	￥ 1,350.00
100 mg	￥ 2,250.00

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生物活性

靶点信息

IKCa1 (KCa3.1)
20 nM(Kd)

溶解度 *

In vitro (25°C)	DMSO	0.36 mg/mL (1.04 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	2% DMSO+corn oil	1 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	29 mL	144.99 mL	289.99 mL
0.5 mM	5.8 mL	29 mL	58 mL
1 mM	2.9 mL	14.5 mL	29 mL
5 mM	0.58 mL	2.9 mL	5.8 mL

*The above data is based on the productmolecular weight 344.84. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A12783
作用机制	Blocker (阻断剂)
M. Wt	344.84
Formula	C22H17ClN2
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	289905-88-0
Synonyms	TRAM34, TRAM 34
SMILES	C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3Cl)N4C=CC=N4