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Triciribine，也称为API-2，可抑制Akt的磷酸化水平和激酶活性。
靶点信息
| HIV-1 (CEM-SS, H9, H9IIIB, U1 cells) | Akt (PC3 cells) | |||
| 20 nM | 130 nM |
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 31.22 mL | 156.1 mL | 312.2 mL |
| 0.5 mM | 6.24 mL | 31.22 mL | 62.44 mL |
| 1 mM | 3.12 mL | 15.61 mL | 31.22 mL |
| 5 mM | 0.62 mL | 3.12 mL | 6.24 mL |
*The above data is based on the productmolecular weight 320.31. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A13210 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 320.31 |
| Formula | C13H16N6O4 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 35943-35-2 |
| Synonyms | NSC 154020, TCN, API-2 |
| SMILES | CN1C2=NC=NC3=C2C(=CN3[C@H]4[C@@H]([C@@H]([C@H](O4)CO)O)O)C(=N1)N |
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