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Vandetanib trifluoroacetate是一种有效的VEGFR2抑制剂，IC50为40 nM。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 16.97 mL | 84.83 mL | 169.67 mL |
| 0.5 mM | 3.39 mL | 16.97 mL | 33.93 mL |
| 1 mM | 1.7 mL | 8.48 mL | 16.97 mL |
| 5 mM | 0.34 mL | 1.7 mL | 3.39 mL |
*The above data is based on the productmolecular weight 589.38. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A15272 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 589.38 |
| Formula | C24H25BrF4N4O4 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 338992-53-3 |
| Synonyms | Zactima trifluoroacetate, ZD6474 trifluoroacetate, ZD-6474 trifluoroacetate, ZD 6474 trifluoroacetate |
| SMILES | CN1CCC(CC1)COC2=C(C=C3C(=C2)N=CN=C3NC4=C(C=C(C=C4)Br)F)OC.C(=O)(C(F)(F)F)O |
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