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Vernakalant hydrochloride是一种研究性混合离子通道阻滞剂，可以以2至5 mg/kg的剂量终止人的急性心房纤颤（AF），并且与现有药物相比，对房颤的选择性更高。在抗心律不齐的治疗中。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 25.91 mL | 129.56 mL | 259.11 mL |
| 0.5 mM | 5.18 mL | 25.91 mL | 51.82 mL |
| 1 mM | 2.59 mL | 12.96 mL | 25.91 mL |
| 5 mM | 0.52 mL | 2.59 mL | 5.18 mL |
*The above data is based on the productmolecular weight 385.93. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A15275 |
|---|---|
| 作用机制 | Blocker (阻断剂) |
| M. Wt | 385.93 |
| Formula | C20H32ClNO4 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 748810-28-8 |
| Synonyms | RSD1235 hydrochloride, RSD 1235 hydrochloride, RSD-1235 hydrochloride |
| SMILES | COC1=C(C=C(C=C1)CCOC2CCCCC2N3CCC(C3)O)OC.Cl |
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