Vorapaxar (SCH 530348)

目录号: A12832

PAR-1 拮抗剂

Vorapaxar (SCH 530348)

Vorapaxar (SCH 530348) Chemical Structure

CAS NO. 618385-01-6

Vorapaxar (SCH 530348)是一种有效的口服活性凝血酶受体(PAR-1)拮抗剂,Ki为8.1 nM。

库存: 现货

规格 价格 数量
5 mg
¥ 1,300.00
10 mg
¥ 2,300.00
25 mg
¥ 4,600.00
50 mg
¥ 6,800.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Vorapaxar (SCH 530348)是一种有效的口服活性凝血酶受体(PAR-1)拮抗剂,Ki为8.1 nM。
靶点信息
PAR-1
8.1 nM(Ki)
In vitro DMSO 96 mg/mL (194.89 mM)
Water Insoluble
Ethanol 96 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.3 mL 101.51 mL 203.01 mL
0.5 mM 4.06 mL 20.3 mL 40.6 mL
1 mM 2.03 mL 10.15 mL 20.3 mL
5 mM 0.41 mL 2.03 mL 4.06 mL

*The above data is based on the productmolecular weight 492.58. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A12832
作用机制 Antagonist (拮抗剂)
M. Wt 492.58
Formula C29H33FN2O4
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 618385-01-6
Synonyms SCH530348, SCH-530348, MK-5348, MK5348, MK 5348
SMILES CCOC(=O)N[C@@H]1CC[C@@H]2[C@@H](C1)C[C@@H]3[C@H]([C@H]2/C=C/C4=NC=C(C=C4)C5=CC(=CC=C5)F)[C@H](OC3=O)C

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