WAY-362450

Name: WAY-362450
SKU: A11186

目录号: A11186

FXR 激动剂

Product Citations (2)

WAY-362450 Chemical Structure

CAS NO. 629664-81-9

WAY-362450是一种高效，选择性和口服可生物利用的法呢类X受体（FXR）激动剂（EC50：4 nM，eff = 149％）。

库存：现货

规格	价格	数量
5 mg	￥ 900.00
10 mg	￥ 1,500.00
50 mg	￥ 4,800.00
100 mg	￥ 7,800.00
10mM * 1mL in DMSO	￥ 1,000.00

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生物活性

WAY-362450是一种高效，选择性和口服可生物利用的法呢类X受体（FXR）激动剂（EC50：4 nM，eff = 149％）。

靶点信息

FXR
4 nM(EC50)

溶解度 *

In vitro (25°C)	DMSO	Warmed: 31 mg/mL (70.7 mM)
	Water	Insoluble
	Ethanol	2 mg/mL (4.56 mM)
In vivo	NMP+PEG300 (10+90, v+v)	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.81 mL	114.03 mL	228.07 mL
0.5 mM	4.56 mL	22.81 mL	45.61 mL
1 mM	2.28 mL	11.4 mL	22.81 mL
5 mM	0.46 mL	2.28 mL	4.56 mL

*The above data is based on the productmolecular weight 438.47. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A11186
作用机制	Agonist (激动剂)
M. Wt	438.47
Formula	C25H24F2N2O3
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	629664-81-9
Synonyms	WAY362450, XL335
SMILES	CC(C)OC(=O)C1=CN(CC(C2=C1NC3=CC=CC=C32)(C)C)C(=O)C4=CC(=C(C=C4)F)F