WHI-P 154

目录号: A14049

JAK3 抑制剂

WHI-P 154

WHI-P 154 Chemical Structure

CAS NO. 211555-04-3

WHI-P 154是一种JAK3抑制剂,IC50 = 1.8uM。WHI-P 154还在体外抑制巨噬细胞中的STAT1激活,iNOS表达和NO生成。

库存: 现货

规格 价格 数量
10 mg
¥ 800.00
25 mg
¥ 1,600.00
50 mg
¥ 3,000.00
10mM * 1mL in DMSO
¥ 850.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

WHI-P 154是一种JAK3抑制剂,IC50 = 1.8uM。WHI-P 154还在体外抑制巨噬细胞中的STAT1激活,iNOS表达和NO生成。
靶点信息
EGFR VEGFR Src JAK3
4 nM100 nM100 nM1.8 μM
In vitro (25°C) DMSO 74 mg/mL (196.7 mM)
Water Insoluble
Ethanol Insoluble
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.58 mL 132.91 mL 265.82 mL
0.5 mM 5.32 mL 26.58 mL 53.16 mL
1 mM 2.66 mL 13.29 mL 26.58 mL
5 mM 0.53 mL 2.66 mL 5.32 mL

*The above data is based on the productmolecular weight 376.2. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A14049
作用机制 Inhibitor (抑制剂)
M. Wt 376.2
Formula C16H14BrN3O3
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 211555-04-3
Synonyms WHI-P154
SMILES COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)O)Br)OC

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