ZCL-278

Name: ZCL-278
SKU: A13403

目录号: A13403

Cdc42 GTPase 抑制剂

ZCL-278 Chemical Structure

CAS NO. 587841-73-4

ZCL-278是Cdc42的选择性抑制剂。以Cdc42鸟嘌呤核苷酸交换因子交叉蛋白(ITSN)的结合位点为目标。抑制Cdc42介导的细胞效应，包括3T3成纤维细胞中微峰的形成和初生新生皮质神经元中的神经元分支。还抑制PC3细胞的细胞运动和迁移，无细胞毒性作用。

库存：现货

规格	价格	数量
10 mg	￥ 600.00
25 mg	￥ 1,200.00
50 mg	￥ 2,000.00
100 mg	￥ 3,500.00
10mM * 1mL in DMSO	￥ 750.00

或

添加到收藏

产品仅用于科学研究，不针对患者销售，望谅解.

产品详情

生物活性

靶点信息

Cdc42 GTPase
11.4 μM(Kd)

溶解度 *

In vitro	DMSO	99 mg/mL (169.26 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	17.1 mL	85.49 mL	170.97 mL
0.5 mM	3.42 mL	17.1 mL	34.19 mL
1 mM	1.71 mL	8.55 mL	17.1 mL
5 mM	0.34 mL	1.71 mL	3.42 mL

*The above data is based on the productmolecular weight 584.89. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A13403
作用机制	Inhibitor (抑制剂)
M. Wt	584.89
Formula	C21H19BrClN5O4S2
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	587841-73-4
Synonyms	ZCL278, ZCL 278
SMILES	CC1=CC(=NC(=N1)NS(=O)(=O)C2=CC=C(C=C2)NC(=S)NC(=O)COC3=C(C=C(C=C3)Br)Cl)C