GPCR / G Protein

12 个项目

每页

设置升序顺序
  1. Mirabegron

    Catalog No. A12861
    Quick View
    β3 adrenergic receptor activator
    Mirabegron是一种选择性的beta3-adrenoceptor(β3肾上腺素受体)激动剂,EC50为22.4 nM。是有效的膀胱松弛药和糖尿病药物。 了解更多
  2. C-DIM12

    Catalog No. A15936
    Quick View
    Nurr1 activator
    C-DIM12是Nurr1的新型合成活化剂。C-DIM12诱导多巴胺能基因表达,并在体外防御6-羟基多巴胺的神经毒性。 了解更多
  3. 20(S)-Hydroxycholesterol

    Catalog No. A21850
    Quick View
    Smo allosteric activator
    20(S)-hydroxyCholesterol (20α-Hydroxycholesterol) is an allosteric activator of the oncoprotein smoothened (Smo) that activates the hedgehog (Hh) signaling pathway with an EC50 of 3 μM in a gene transcription reporter assay using NIH3T3 cells. 了解更多
  4. SRT3190

    Catalog No. A11577
    Quick View
    SIRT1 activator
    SRT3190是一种强效cxcr2配体。 了解更多
  5. GPR40 Activator 1

    Catalog No. A21154
    Quick View
    GPR40 activator
    GPR40 Activator 1 is a potent GPR40 activator for treatment of type 2 diabetes. 了解更多
  6. GPR40 Activator 2

    Catalog No. A21642
    Quick View
    GPR40 activator
    GPR40 Activator 2 is a potent GPR40 activator from patents WO 2012147516 A1, WO 2012046869A1 and WO 2011078371 A1. 了解更多
  7. Saikosaponin B2

    Catalog No. A14600
    Quick View
    Prostanoid activator
    Saikosaponin B2是皂苷激活剂。 了解更多
  8. Cinaciguat

    Catalog No. A21283
    Quick View
    sGC activator
    Cinaciguat is an activator of guanylate cyclase (sGC), and used for acute decompensated heart failure. 了解更多
  9. BAY 41-2272

    Catalog No. A15891
    Quick View
    sGC activator?
    BAY 41-2272是一种直接且不依赖NO的可溶性鸟苷酸环化酶(sGC)刺激物。 了解更多
  10. YC-1 (Lificiguat)

    Catalog No. A12402
    Quick View
    sGC activator
    YC-1 (Lificiguat)是可溶性胍基环化酶(sGC)的直接活化剂,独立于一氧化氮。 了解更多
  11. AMG 073 (Cinacalcet)

    Catalog No. A11314
    Quick View
    CaSR activator
    AMG 073 (Cinacalcet)是一类治疗甲状旁腺功能亢进的新型化合物。 了解更多
  12. AMG-073 HCl (Cinacalcet HCl)

    Catalog No. A10219
    Quick View
    CaSR activator
    AMG-073 HCl(Cinacalcet HCl)是一种用于治疗甲状旁腺功能亢进的化合物,称为拟钙剂,通过增加甲状旁腺钙敏感受体(CaR)对细胞外钙的敏感性来减少甲状旁腺激素(PTH)的合成和分泌 。 了解更多

12 个项目

每页

设置升序顺序
Rewards