微信关注
Total item
Cart Subtotal
￥ 0.00 GPCR / G Protein
-
Flopropione
Catalog No. A16550 5-HT1A receptor antagonist/COMT inhibitorFlopropione是5-HT1A受体拮抗剂，也是儿茶酚-邻甲基转移酶（COMT）抑制剂。 了解更多 -
Vortioxetine
Catalog No. A21266 5-HT1A/5-HT1B/5-HT3A/5-HT7 receptor/SERT inhibitorVortioxetine is a inhibitor of 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT, with Ki values of 15 nM, 33 nM, 3.7 nM, 19 nM and 1.6 nM, respectively. 了解更多 -
Vilazodone D8
Catalog No. A21876 SSR inhibitor / 5-HT1A receptor partial agonistVilazodone D8 is the a deuterium labeled vilazodone, which is a combined serotonin specific reuptake inhibitor (SSRI) and 5-HT1A receptor partial agonist. 了解更多 -
Eplivanserin mixture
Catalog No. A21987 serotonin reuptake inhibitor/5-HT2A receptor antagonistEplivanserin mixture is a selective serotonin reuptake inhibitor and a 5-HT2A receptor antagonist, extracted from patent WO 2005/002578 A1. 了解更多 -
Vilazodone
Catalog No. A11116 Serotonin reuptake 抑制剂Vilazodone充当5-羟色胺再摄取抑制剂（IC50 = 0.5 nM）和5-HT1A受体部分激动剂（IC50 = 0.2 nM； IA =?60-70％）。 了解更多 -
Sibutramine hydrochloride
Catalog No. A12397 -
Levomilnacipran HCl
Catalog No. A14391 -
Edivoxetine HCl
Catalog No. A13865 -
Norfluoxetine
Catalog No. A13458 serotonin uptake 抑制剂Norfluoxetine是抗抑郁药氟西汀的活性代谢物，抑制5-羟色胺的摄取，pKi值为7.35.1氟西汀的S-对映体的5-羟色胺再摄取阻断能力是R-对映体的20倍（pKis分别为7.86和6.51）。 了解更多 -
Atomoxetine HCl
Catalog No. A13424 norepinephrine (NE) transporter 抑制剂Atomoxetine HCl是SLC6A2的一种竞争性特异性抑制剂，同时在大鼠下丘脑突触体中显示出微弱的ST和DAT抑制作用。 了解更多 -
Asenapine HCl
Catalog No. A15002 adrenergic receptor/5-HT receptor 抑制剂Asenapine hydrochloride抑制肾上腺素能受体（α1，α2A，α2B，α2C）的Ki为0.25-1.2 nM，还抑制5-HT受体（1A，1B，2A，2B，2C，5A，6、7），Ki为0.03- 4.0 nM。 了解更多 -
Desvenlafaxine succinate hydrate
Catalog No. A15491 serotonin (5-HT)/norepinephrine (NE) reuptake 抑制剂Desvenlafaxine succinate hydrate是一种新型5-羟色胺(5-HT)转运蛋白 和去甲肾上腺素(NE)转运蛋白重吸收抑制剂，Ki值分别为40.2 nM和558.4 nM 了解更多 -
Eucalyptol
Catalog No. A15662 -
Nefazodone hydrochloride
Catalog No. A17622 5-HT2 receptors inhibitorNefazodone HCl is an inhibitor of 5-HT2 receptors, SERT, NET, and hERG K+ channels used to treat mood disorders. It decreases immobility time in the forced swim test. 了解更多 -
Apalutamide (ARN-509)
Catalog No. A11923 Androgen Receptor 抑制剂Apalutamide (ARN-509)是一种具有潜在抗肿瘤活性的雄激素受体拮抗剂，IC50 为 16 nM。ARN-509与靶组织中的AR结合，从而阻止了雄激素诱导的受体激活，并促进了无法转运至细胞核的无活性复合物的形成。这防止了AR应答基因的结合和转录。 了解更多 -
Phenoxybenzamine hydrochloride
Catalog No. A10719 α-adrenergic (AR) 拮抗剂/CaM 抑制剂Phenoxybenzamine hydrochloride是一种细胞可渗透的，非特异性的，不可逆的α-肾上腺素（AR）拮抗剂，也可作为CaM抑制剂。 了解更多 -
Maprotiline hydrochloride
Catalog No. A10555 -
Anisodamine
Catalog No. A18215 alpha-1 adrenergic receptors / mAChRs inhibitorAnisodamine is an inhibitor of alpha-1 adrenergic receptors and mAChRs isolated from Chinese solanacea plant. 了解更多 -
Orphenadrine citrate
Catalog No. A11712 -
Rupatadine Fumarate
Catalog No. A12356 PAFR 抑制剂/H1 receptor 抑制剂Rupatadine Fumarate是PAFR和组胺(H1)受体的抑制剂，Ki分别为550和102 nM。 了解更多 -
Rupatadine
Catalog No. A11222 PAFR 抑制剂/H1 receptor 抑制剂Rupatadine是PAFR和组胺（H1）受体的抑制剂，Ki分别为550和102 nM。 了解更多 -
Fexofenadine HCl
Catalog No. A11859 COX 抑制剂/histamine H1 receptor 激动剂Fexofenadine Hydrochloride是一种抗组胺药，可抑制Cox-1，Cox-2，并且是组胺H1受体激动剂，IC50为246 nM。 了解更多 -
Antazoline HCl
Catalog No. A16411 -
Azatadine dimaleate
Catalog No. A16418 -
Nepicastat (free base) (SYN-117)
Catalog No. A10637 dopamine beta-hydroxylase 抑制剂Nepicastat (free base) (SYN-117)是多巴胺β-羟化酶的抑制剂，该酶催化多巴胺向去甲肾上腺素的转化。 了解更多 -
Phenylpiracetam
Catalog No. A15211 -
Loxapine Succinate
Catalog No. A17347 D2DR and D4DR inhibitorLoxapine Succinate is a D2DR and D4DR inhibitor and serotonergic receptor antagonist. Loxapine succinate is an antipsychotic agent used in schizophrenia. 了解更多 -
Promazine hydrochloride
Catalog No. A17638 D2DR inhibitorPromazine Hydrochloride is a phenothiazine compound and D2DR inhibitor. Promazine Hydrochloride has been employed in studies investigating dopamine-stimulated glycosylation of brain proteins in vitro. It has actions similar to chlorpromazine but with less antipsychotic activity. 了解更多 -
Zamicastat
Catalog No. A13672 dopamine β-hydroxylase (DBH) inhibitorZamicastat (BIA 5-1058) is a dopamine β-hydroxylase (DBH) inhibitor that could cross the blood-brain barrier (BBB) and cause central as well as peripheral effects. 了解更多 -
Pentiapine
Catalog No. A12512 -
Vanoxerine
Catalog No. A21922 dopamine reuptake inhibitorVanoxerine (GBR-12909) is a competitive, potent, and highly selective dopamine reuptake inhibitor (Ki=1 nM). 了解更多 -
Radafaxine hydrochloride
Catalog No. A20951 dopamine transporter/norepinephrine transportertransporters inhibitorRadafaxine hydrochloride (GW-353162A) is a DAT (dopamine transporter) and NET(norepinephrine transporter) transporters inhibitor, and nAChR family modulator. 了解更多 -
Vanoxerine 2HCl (GBR-12909)
Catalog No. A10725 dopamine re-uptake 抑制剂Vanoxerine 2HCl (GBR-12909)是哌嗪衍生物，是一种有效的、选择性的多巴胺摄取（dopamine uptake）抑制剂。 了解更多 -
Lurasidone (SM13496)
Catalog No. A11214 Dopamine D2 抑制剂Lurasidone (SM-13496)是dopamine D2和5-HT7的拮抗剂，IC50 值分别为 1.68 和 0.495 nM。Lurasidone (SM-13496) 也是 5-HT1A 受体的部分激动剂。 了解更多 -
GBR-12935 2HCl
Catalog No. A11937 -
Haloperidol (Haldol)
Catalog No. A10446 -
GBR 12783 dihydrochloride
Catalog No. A13128 dopamine uptake 抑制剂GBR 12783 dihydrochloride是一种非常有效的选择性多巴胺摄取抑制剂（抑制大鼠纹状体突触体中[3H]-多巴胺摄取的IC50为1.8 nM）。 了解更多 -
LDE225 Diphosphate
Catalog No. A12774 Smoothened 抑制剂LDE225 Diphosphate 是一种具有潜在抗肿瘤活性的口服生物利用小分子平滑（Smo）拮抗剂。抑制Hedgehog (Hh)信号通路，无细胞试验中IC50分别为1.3 nM (小鼠)和2.5 nM(人)。 了解更多 -
PF-5274857
Catalog No. A12775 Smoothened 抑制剂PF-5274857是一种新型Smo拮抗剂，它以4.6±1.1 nmol/L的K（i）特异性结合Smo，并以2.7±1.4 nmol/L的IC（50）完全阻断下游基因Gli1的转录活性。在细胞中。 了解更多 -
BMS-833923 (XL-139)
Catalog No. A13204 Smoothened 抑制剂BMS-833923 (XL-139)是一种生物可利用的小分子SMO(平滑)抑制剂，具有潜在的抗肿瘤活性。 了解更多 -
Glasdegib (PF-04449913)
Catalog No. A13881 -
Jervine
Catalog No. A16221
FILTER BY:
Filtering:
- 作用机制: Inhibitor (抑制剂) 删除该内容
购物选项
- 分类
-
- 5-HT Receptors (16)
- Adrenergic Receptors (7)
- Histamine Receptors (6)
- Metabotropic glutamate receptors (mGluR) (1)
- Smoothened Receptors (7)
- CXCR (3)
- G Protein (3)
- Platelet-Activating Factor (PAF) Receptors (2)
- Endothelin Receptors (1)
- Prostanoid Receptors (4)
- Adenosine Receptors (5)
- Cannabinoid Receptors (2)
- Protease-Activated Receptors (PAR) (1)
- S1P Receptor (10)
- Guanylate Cyclase (1)
- cAMP (3)
- 靶点
ADOOQ 产品质量保证
We promise all products to perform as described.