Adrenergic Receptors

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Asenapine

Catalog No. A18010
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adrenergic receptor inhibitor

Asenapine(Org 5222) inhibits adrenergic receptor (α1, α2A, α2B, α2C) with Ki of 0.25-1.2 nM and also inhibits 5-HT receptor (1A, 1B, 2A, 2B, 2C, 5A, 6, 7) with Ki of 0.03-4.0 nM. 了解更多

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Apalutamide (ARN-509)

Catalog No. A11923
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Androgen Receptor 抑制剂

Apalutamide (ARN-509)是一种具有潜在抗肿瘤活性的雄激素受体拮抗剂，IC50 为 16 nM。ARN-509与靶组织中的AR结合，从而阻止了雄激素诱导的受体激活，并促进了无法转运至细胞核的无活性复合物的形成。这防止了AR应答基因的结合和转录。了解更多

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- Frédérique Mittler, .et al. High-Content Monitoring of Drug Effects in a 3D Spheroid Model, Front Oncol, 2017, 7: 293 PMID: 29322028
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Phenoxybenzamine hydrochloride

Catalog No. A10719
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α-adrenergic (AR) 拮抗剂/CaM 抑制剂

Phenoxybenzamine hydrochloride是一种细胞可渗透的，非特异性的，不可逆的α-肾上腺素（AR）拮抗剂，也可作为CaM抑制剂。了解更多

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Maprotiline hydrochloride

Catalog No. A10555
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noradrenalin re-uptake 抑制剂

Maprotiline hydrochloride是选择性去甲肾上腺素再摄取抑制剂。了解更多

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Asenapine HCl

Catalog No. A15002
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adrenergic receptor/5-HT receptor 抑制剂

Asenapine hydrochloride抑制肾上腺素能受体（α1，α2A，α2B，α2C）的Ki为0.25-1.2 nM，还抑制5-HT受体（1A，1B，2A，2B，2C，5A，6、7），Ki为0.03- 4.0 nM。了解更多

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Desvenlafaxine succinate hydrate

Catalog No. A15491
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serotonin (5-HT)/norepinephrine (NE) reuptake 抑制剂

Desvenlafaxine succinate hydrate是一种新型5-羟色胺(5-HT)转运蛋白和去甲肾上腺素(NE)转运蛋白重吸收抑制剂，Ki值分别为40.2 nM和558.4 nM 了解更多

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Anisodamine

Catalog No. A18215
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alpha-1 adrenergic receptors / mAChRs inhibitor

Anisodamine is an inhibitor of alpha-1 adrenergic receptors and mAChRs isolated from Chinese solanacea plant. 了解更多

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