Afloqualone

目录号: A17276

GABA receptor agonist

Afloqualone

Afloqualone Chemical Structure

CAS NO. 56287-74-2

Afloqualone, also known as HQ-495, is a centrally acting muscle relaxant. Afloqualone inhibits vestibular nystagmus probably due to both inhibition of selective polysynaptic transmission and enhancement of the effects of GABA and glycine in the lateral vestibular nucleus (LVN), and its GABA-enhancing effect is thought to be attributable to the increased sensitivity of GABA receptors of the LVN neuron site.

库存: 现货

规格 价格 数量
100 mg
¥ 600.00
500 mg
¥ 2,000.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Afloqualone, also known as HQ-495, is a centrally acting muscle relaxant. Afloqualone inhibits vestibular nystagmus probably due to both inhibition of selective polysynaptic transmission and enhancement of the effects of GABA and glycine in the lateral vestibular nucleus (LVN), and its GABA-enhancing effect is thought to be attributable to the increased sensitivity of GABA receptors of the LVN neuron site.
In vitro DMSO 53 mg/mL (187.08 mM)
Water Insoluble
Ethanol 27 mg/mL (95.3 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 35.3 mL 176.49 mL 352.97 mL
0.5 mM 7.06 mL 35.3 mL 70.59 mL
1 mM 3.53 mL 17.65 mL 35.3 mL
5 mM 0.71 mL 3.53 mL 7.06 mL

*The above data is based on the productmolecular weight 283.3064. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A17276
作用机制 Agonist (激动剂)
M. Wt 283.3064
Formula C16H14FN3O
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 56287-74-2
Synonyms HQ-495; HQ495; HQ 495. Afloqualone
SMILES O=C1N(C2=CC=CC=C2C)C(CF)=NC3=C1C=C(N)C=C3

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