BMS 777607

目录号: A21638

c-Met/Axl/Ron/Tyro3 inhibitor

BMS 777607

BMS 777607 Chemical Structure

CAS NO. 1025720-94-8

BMS 777607 is a Met-related inhibitor for c-Met, Axl, Ron and Tyro3 with IC50s of 3.9 nM, 1.1 nM, 1.8 nM and 4.3 nM, respectively.

库存: 现货

规格 价格 数量
5 mg
¥ 760.00
10 mg
¥ 1,300.00
50 mg
¥ 3,860.00
100 mg
¥ 7,730.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

BMS 777607 is a Met-related inhibitor for c-Met, Axl, Ron and Tyro3 with IC50s of 3.9 nM, 1.1 nM, 1.8 nM and 4.3 nM, respectively.
In vitro (25°C) DMSO 40 mg/mL (77.98 mM)
Water Insoluble
Ethanol Insoluble
In vivo 4% DMSO+45% PEG 300+5% Tween 80+ddH2O 4 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.5 mL 97.49 mL 194.97 mL
0.5 mM 3.9 mL 19.5 mL 38.99 mL
1 mM 1.95 mL 9.75 mL 19.5 mL
5 mM 0.39 mL 1.95 mL 3.9 mL

*The above data is based on the productmolecular weight 512.89. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A21638
作用机制 Inhibitor (抑制剂)
M. Wt 512.89
Formula C25H19ClF2N4O4
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1025720-94-8
Synonyms BMS777607, BMS-777607; BMS 817378, BMS817378, BMS-817378
SMILES O=C(NC1=CC=C(C(F)=C1)OC2=C(C(N)=NC=C2)Cl)C3=C(C=CN(C3=O)C4=CC=C(C=C4)F)OCC

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