“ab fubinaca”的搜索结果

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  1. Tebanicline hydrochloride

    Catalog No. A21918
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    nAChR modulator
    Tebanicline hydrochloride (ABT594 hydrochloride) is a nAChR modulator with potent, orally effective analgesic activity. 了解更多
  2. Anandamide

    Catalog No. A21835
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    immune modulator
    Anandamide is an immune modulator in the central nervous system acts via not only cannabinoid receptors (CB1 and CB2) but also other targets (e.g., GPR18/GPR55). 了解更多
  3. 3-Methoxytyramine

    Catalog No. A21676
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    neuromodulator
    3-Methoxytyramine, a well known extracellular metabolite of 3-hydroxytyramine/dopamine, is a neuromodulator. 了解更多
  4. NS11394

    Catalog No. A21425
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    GABA(A) receptor modulator
    NS11394 is a potent and subtype-selective GABA(A) receptor-positive modulator; possesses a functional efficacy selectivity profile of alpha(5) > alpha(3) > alpha(2) > alpha(1) at GABA(A) alpha subunit-containing receptors. 了解更多
  5. Foliglurax monohydrochloride

    Catalog No. A21384
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    glutamate receptor 4 modulator
    Foliglurax monohydrochloride (PXT002331 monohydrochloride) is a highly selective and potent, brain-penetrant metabotropic glutamate receptor 4 positive allosteric modulator (mGluR4 PAM) , with an EC50 of 79 nM. Antiparkinsonian effect. 了解更多
  6. Basmisanil

    Catalog No. A21321
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    GABAAα5 modulator
    Basmisanil is a highly selective GABAAα5 negative allosteric modulator. 了解更多
  7. Basimglurant

    Catalog No. A21225
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    mGlu5 negative allosteric modulator
    Basimglurant (RG7090) is a potent, selective and orally available mGlu5 negative allosteric modulator with a Kd of 1.1 nM. 了解更多
  8. RAD140

    Catalog No. A21205
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    androgen receptor modulator
    RAD140 is a potent, orally bioavailable, nonsteroidal selective androgen receptor modulator (SARM). 了解更多
  9. GLPG0492

    Catalog No. A21105
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    androgen receptor modulator
    GLPG0492 is a novel selective androgen receptor modulator; exhibited anabolic activity on muscle, strongly dissociated from the androgenic activity on prostate after oral dosing. 了解更多
  10. VU6001376

    Catalog No. A13763
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    metabotropic glutamate receptor 4 modulator
    VU6001376 is a potent and selective positive allosteric modulator of the metabotropic glutamate receptor 4 (mGlu4 PAM) with an EC50 of 50.1 nM. 了解更多
  11. GNE 0723

    Catalog No. A12757
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    NMDAR modulator
    GNE 0723 is a brain permeable positive allosteric modulator of NMDAR, with an EC50 of 21 nM for GluN2A, 7.4 and 6.2 μM for GluN2C and GluN2D, respectively. 了解更多
  12. Insulin levels modulator

    Catalog No. A13315
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    Insulin levels modulator could be used to treat diabetes. 了解更多
  13. MA-0204

    Catalog No. A19031
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    PPARδ modulator
    MA-0204 is a potent, highly selective and orally available peroxisome proliferator activated receptor δ (PPARδ) modulator with EC50s of 0.4 nM, 7.9 nM and 10 nM for human, mouse and rat PPARδ, respectively. Potential treatment for Duchene Muscular Dystrophy (DMD). 了解更多
  14. E6130

    Catalog No. A20056
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    CX3CR1 modulator
    E6130 is an orally available and highly selective CX3CR1 modulator, that may be effective for treatment of inflammatory bowel disease. 了解更多
  15. BNC375

    Catalog No. A18503
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    α7 nAChR Modulator
    BNC375 is a Potent, Selective, and Orally Available Type I Positive Allosteric Modulator of α7 nAChRs. 了解更多
  16. PZ-2891

    Catalog No. A18880
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    PANK modulator
    PZ-2891 is an orally bioavailable, brain penetrant pantothenate kinase (PANK) modulator. PZ-2891 act as an orthosteric inhibitor at high concentrations and an allosteric activator at lower sub-saturating concentrations. PZ-2891 inhibits human pantothenate kinases PANK1β, PANK2, and PANK3 with IC50s of 40.2 nM, 0.7 nM and 1.3 nM, respectively. 了解更多
  17. VU0652835

    Catalog No. A18885
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    mGlu5 modulator
    VU0652835 is a metabotropic glutamate receptor subtype 5 (mGlu5) negative allosteric modulator with an IC50 of 81 nM. 了解更多
  18. Lasofoxifene Tartrate

    Catalog No. A18097
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    selective Estrogen receptor modulator
    Lasofoxifene tartrate is a third-generation selective estrogen receptor modulator. 了解更多
    • 最新产品

    PUN30119

    Catalog No. A17232
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    PUN30119, also known as Imidazole ketone erastin (IKE), is a potent, metabolically stable inhibitor of system xc- and inducer of ferroptosis potentially suitable for in vivo applications. 了解更多
    • 最新产品

    KL1333

    Catalog No. A17234
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    NAD+ Modulator
    KL1333 is an orally available, small organic molecule that reacts with NAD(P)H:quinone oxidoreductase 1 (NQO1) as a substrate, resulting in increases in intracellular NAD+ levels via NADH oxidation. KL-1333 Improves Energy Metabolism and Mitochondrial Dysfunction in MELAS Fibroblasts. 了解更多
  19. NGP-555

    Catalog No. A17051
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    γ-Secretase Modulator
    NGP-555是一种γ-分泌酶调节剂,具有选择性机制,可减少Abeta 42,同时提高较短的Abeta形式,例如Abeta 37和38。 了解更多
  20. Lorediplon

    Catalog No. A13449
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    GABAA receptor modulator
    Lorediplon 是一种新型的非苯二氮卓类催眠药,作为GABAA受体调节剂。 了解更多
  21. CTP354

    Catalog No. A15939
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    GABA(A) modulator
    CTP354是一种新型的氘化亚型选择性GABA(A)调节剂。 了解更多
  22. Indiplon

    Catalog No. A13769
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    GABAA receptor modulator
    Indiplon是吡唑并嘧啶,可作为GABAA受体的高亲和力正变构调节剂,以剂量依赖和可逆的方式增强GABA活化的氯离子电流。 了解更多
  23. Tonabersat (SB-220453)

    Catalog No. A11593
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    gap-junction modulator
    Tonabersat (SB-220453)是一种新颖的苯并吡喃衍生物,是一种gap-junction调节剂。 了解更多

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