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Aripiprazole (D8)
Catalog No. A22004 human 5-HT1A receptor partial agonistAripiprazole D8 (OPC-14597 D8) is the deuterium labeled Aripiprazole, which is a human 5-HT1A receptor partial agonist with a Ki of 4.2 nM. 了解更多 -
Bambuterol
Catalog No. A21955 beta-adrenoceptor agonistBambuterol ((??)-Bambuterol; KWD-2183) is a long acting beta-adrenoceptor agonist (LABA) used in the treatment of asthma; it also is a prodrug of terbutaline. 了解更多 -
MT-7716 free base
Catalog No. A21928 non-peptide nociceptin receptor (NOP) agonistMT-7716 free base (W-212393) is a selective non-peptide nociceptin receptor (NOP) agonist and promising potential treatment drug for alcohol abuse and relapse prevention. 了解更多 -
Vilazodone D8
Catalog No. A21876 SSR inhibitor / 5-HT1A receptor partial agonistVilazodone D8 is the a deuterium labeled vilazodone, which is a combined serotonin specific reuptake inhibitor (SSRI) and 5-HT1A receptor partial agonist. 了解更多 -
Gaboxadol hydrochloride
Catalog No. A21730 GABAA receptors agonistGaboxadol hydrochloride (Lu 02-030 hydrochloride) is a selective agonist at GABAA receptors that contain α4-δ subunits, and has anxiolytic and sedative effects. 了解更多 -
Taranabant ((1R,2R)stereoisomer)
Catalog No. A21705 CB1 receptor inverse agonistTaranabant (1R,2R)stereoisomer is the R-enantiomer of Taranabant. Taranabant is a highly potent and selective cannabinoid 1 (CB1) receptor inverse agonist. 了解更多 -
diABZI STING agonist-1 trihydrochloride
Catalog No. A21694 STING receptor agonistdiABZI STING agonist-1 (trihydrochloride) is a selective stimulator of interferon genes (STING) receptor agonist, with an EC50s of 130 for human PBMCs. 了解更多 -
diABZI STING agonist-1
Catalog No. A21688 STING receptor agonistdiABZI STING agonist-1 is a selective stimulator of interferon genes (STING) receptor agonist, with an EC50s of 130 nM for human PBMCs. 了解更多 -
RGX-104 free Acid
Catalog No. A21513 LXR agonistRGX-104 free Acid is an orally bioavailable and potent liver-X nuclear hormone receptor (LXR) agonist that modulates innate immunity via transcriptional activation of the ApoE gene. 了解更多 -
CP-409092 hydrochloride
Catalog No. A21397 GABAA receptor partial agonistCP-409092 hydrochloride is a partial agonist of GABAA receptor, with anti-anxiety activity. 了解更多 -
Prinaberel
Catalog No. A21255 ERbeta agonistPrinaberel(ERB-041) is a potent and selective ERbeta agonist; being >200-fold selective for ERbeta. 了解更多 -
Cutamesine
Catalog No. A21152 sigma 1 receptor agonistCutamesine (SA4503; AGY-94806) is a selective sigma 1 receptor(??1R) agonist; high affinity for the sigma 1 receptor subtype labeled by (+)-[3H]pentazocine (IC50= 17.4??1.9 nM); 100-fold less affinity for the sigma 2 receptor. 了解更多 -
Indeglitazar
Catalog No. A21148 PPAR agonistIndeglitazar is an orally available peroxisome proliferator-activated receptor (PPAR) pan-agonist for all three PPAR subtypes alpha (α), delta (δ) and gamma (γ). 了解更多 -
Arhalofenate
Catalog No. A21135 PPARγ agonistArhalofenate (MBX 102) is a selective partial agonist of peroxisome proliferator-activated receptor (PPAR)-γ, used for the treatment of type 2 diabetes. 了解更多 -
Nelonicline
Catalog No. A21079 neuronal nicotinic receptor agonistNelonicline (ABT-126) is a selective neuronal nicotinic receptor agonist. 了解更多 -
(R)-Baclofen
Catalog No. A16680 GABAB receptor agonist(R)-Baclofen(STX209) is a selective GABAB receptor agonist. 了解更多 -
L-Glutamic acid monosodium salt
Catalog No. A16591 excitatory transmitter/agonistL-Glutamic acid monosodium salt acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). (S)-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals. 了解更多 -
Indacaterol maleate
Catalog No. A16585 β-adrenoceptor agonistIndacaterol (QAB149) maleate is an ultra-long-acting β-adrenoceptor agonist. 了解更多 -
(S)-Glutamic acid
Catalog No. A15458 glutamate receptors agonist(S)-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). 了解更多 -
Taranabant
Catalog No. A11578 CB1 receptor inverse agonistTaranabant is a highly potent and selective cannabinoid 1 (CB1) receptor inverse agonist that inhibits the binding and functional activity of various agonists, with a binding Ki of 0.13 nM for the human CB1R in vitro. 了解更多 -
Kynurenic acid sodium
Catalog No. A20000 GPR35/CXCR8 agonistKynurenic acid sodium, an endogenous tryptophan metabolite, is a broad-spectrum antagonist targeting NMDA, glutamate, α7 nicotinic acetylcholine receptor. Kynurenic acid sodium is also an agonist of GPR35/CXCR8. 了解更多 -
MT-7716 hydrochloride
Catalog No. A20004 NOP agonistMT-7716 hydrochloride (W-212393 hydrochloride) is a selective non-peptide nociceptin receptor (NOP) agonist and promising potential treatment drug for alcohol abuse and relapse prevention. 了解更多 -
β3-AR agonist 1
Catalog No. A12777 β3-adrenergic receptor agonistβ3-AR agonist 1 (compound 15) is a highly potent, selective, and orally available β3-adrenergic receptor (β3-AR) agonist (EC50=18 nM), being inactive to β1-, β2-, and α1A-AR (β1/β3, β2/β3, and α1A/β3>556-fold). 了解更多 -
GPR35 agonist 1
Catalog No. A12462 GPR35/CXCR8 agonistGPR35 agonist 1 (compound 50) is a potent and specific G protein-coupled receptor-35 (GPR35)/CXCR8 agonist with an EC50 of 5.8 nM, displays good druggability. 了解更多 -
Radequinil
Catalog No. A13395 BzR partial inverse agonistRadequinil (AC-3933) is a benzodiazepine receptor (BzR) partial inverse agonist. AC-3933 binds to GABA(-) and GABA(+) ligand with Kis of 5.15 and 6.11 nM, respectively. 了解更多 -
Acamprosate calcium
Catalog No. A11308 GABA receptor agonistAcamprosate calcium(Campral EC) is a GABA receptor agonist and modulator of glutamatergic systems; reduces alcohol consumption in animal models of alcohol addiction. 了解更多 -
MRK-016
Catalog No. A12046 GABAA α5 receptor agonistMRK-016 is a selective, orally bioavailable inverse agonist of GABAA α5 receptor, with an EC50 of 3 nM for GABAA α5, and Kis of 0.83, 0.85, 0.77?and 1.4?nM for human?GABAA?α1β3γ2, GABAA?α2β3γ2, GABAA?α3β3γ2, and GABAA?α5β3γ2, respectively; MRK-016 also readily penetrates the CNS. 了解更多 -
ROR agonist-1
Catalog No. A18569 ROR 激动剂ROR agonist-1 is a potent and orally bioavailable inverse agonist of the retinoic acid receptor-related orphan receptor C2 (RORC2), inhibition of IL-17A production from human primary TH 17 cells with a pIC50 of 7.5. 了解更多 -
Semaglutide
Catalog No. A18908 GLP-1 receptor agonistSemaglutide, a long-acting GLP-1 analogue, is a glucagon-like peptide-1 (GLP-1) receptor agonist that can be used in the treatment of type 2 diabetes. 了解更多 -
PF-05231023
Catalog No. A18949 FGF21-receptor agonistPF-05231023, a long-acting fibroblast growth factor 21 (FGF21) analog, is a FGF21-receptor agonist, suitable for development as a potential treatment for T2DM. 了解更多 -
Kynurenic acid
Catalog No. A16581 GPR35/CXCR8 拮抗剂Kynurenic acid, an endogenous tryptophan metabolite, is a broad-spectrum antagonist targeting NMDA, glutamate, α7 nicotinic acetylcholine receptor. Kynurenic acid is also an agonist of GPR35/CXCR8. 了解更多
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