“ab fubinaca”的搜索结果

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  1. Upamostat

    Catalog No. A21035
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    serine protease inhibitor
    Upamostat is a serine protease inhibitor. Upamostat is the orally available prodrug of the WX-UK1, which is a urokinase plasminogen activator (uPA) inhibitor. 了解更多
  2. DBPR108

    Catalog No. A21833
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    DPP4 inhibitor
    DBPR108 is a potent, selective, and orally bioavailable dipeptide-derived inhibitor of DPP4 with IC50 of 15 nM; no inhibition on DDP8 and DPP9. 了解更多
  3. PSI-6206 13CD3

    Catalog No. A21782
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    HCV NS5B polymerase inhibitor
    PSI-6206 13CD3 is the deuterium labeled PSI-6206. PSI-6206 is the deaminated derivative of PSI-6130, which is a potent and selective inhibitor of HCV NS5B polymerase. 了解更多
  4. AZD3839 free base

    Catalog No. A21606
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    BACE1 inhibitor
    AZD3839 (free base) is a potent and selective BACE1 inhibitor with IC50 of 23.6 uM, about 14-fold selectivity over BACE2, also a β-secretase enzyme inhibitor. 了解更多
  5. Dutogliptin

    Catalog No. A21573
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    DPP4 inhibitor
    Dutogliptin (PHX-1149 free base) is an orally available, potent, and selective dipeptidyl peptidase-4 (DPP4) inhibitor for the treatment of type 2 diabetes mellitus. 了解更多
  6. Beclabuvir

    Catalog No. A21511
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    HCV NS5B RNA-dependent RNA polymerase inhibitor
    Beclabuvir is an allosteric inhibitor that binds to thumb site 1 of the hepatitis C virus (HCV) NS5B RNA-dependent RNA polymerase, and inhibits recombinant NS5B proteins from HCV genotypes 1, 3, 4, and 5 with IC50 of < 28 nM. 了解更多
  7. Talabostat

    Catalog No. A14079
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    DPP-IV inhibitor
    Talabostat (Val-boroPro; PT100) is an orally active and nonselective dipeptidyl peptidase IV (DPP-IV) inhibitor (IC50 < 4 nM; Ki = 0.18 nM) and the first clinical inhibitor of fibroblast activation protein (FAP) (IC50 = 560 nM). 了解更多
  8. Mericitabine

    Catalog No. A11539
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    HCV NS5B polymerase inhibitor
    Mericitabine (RG 7128; R-7128) is a nucleoside inhibitor of the HCV NS5B polymerase that acts as an RNA chain terminator and prevents elongation of RNA transcripts during replication. 了解更多
  9. BOC-D-FMK

    Catalog No. A11356
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    caspase inhibitor
    Boc-D-FMK is a cell-permeable, irreversible and broad spectrum caspase inhibitor; inhibits apoptosis stimulated by TNF-α with an IC50 of 39 ?M. 了解更多
  10. EP1013

    Catalog No. A11212
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    caspase inhibitor
    EP1013 is a broad-spectrum caspase selective inhibitor, used in the research of type 1 diabetes. 了解更多
  11. Lanabecestat

    Catalog No. A12282
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    BACE1 inhibitor
    Lanabecestat (AZD3293) is a potent, highly permeable, orally active and blood-brain barrier penetrating BACE1 inhibitor with a Ki of 0.4 nM. 了解更多
  12. PSI-7409

    Catalog No. A13962
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    nucleotide analog HCV inhibitor
    PSI-7409 is the active 5'-triphosphate metabolite of Sofosbuvir (PSI-7977). Sofosbuvir (PSI-7977) is a selective and highly active nucleotide analog inhibitor of HCV. 了解更多
  13. ML604440

    Catalog No. A18826
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    proteasome β1i (LMP2) subunit inhibitor
    ML604440 is a potent, specific and cell permeable proteasome β1i (LMP2) subunit inhibitor. 了解更多
  14. Paritaprevir (ABT-450)

    Catalog No. A17625
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    HCV NS3/4A inhibitor
    Paritaprevir (ABT-450) is a potent non-structural protein 3/4A (NS3/4A) protease inhibitor with EC50s of 1 and 0.21 nM against HCV 1a and 1b, respectively. 了解更多
  15. Ombitasvir (ABT-267)

    Catalog No. A17624
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    HCV NS5A inhibitor
    Ombitasvir is a potent inhibitor of the hepatitis C virus protein NS5A, with EC50s of 0.82 to 19.3 pM against HCV genotypes 1 to 5, and 366 pM against genotype 6a. 了解更多
    • 最新产品

    SNJ-1945

    Catalog No. A17243
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    Calpain inhibitor
    SNJ-1945 is a calpain inhibitor with more favorable retinal penetration, high oral bioavailability, and long half-life. SNJ1945 rescued defective function in lissencephaly. 了解更多
  16. NGP-555

    Catalog No. A17051
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    γ-Secretase Modulator
    NGP-555是一种γ-分泌酶调节剂,具有选择性机制,可减少Abeta 42,同时提高较短的Abeta形式,例如Abeta 37和38。 了解更多
  17. Glecaprevir

    Catalog No. A16948
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    HCV NS3/4A protease 抑制剂
    Glecaprevir,也称为ABT-493和A-1282576,是一种新型的HCV NS3/4A蛋白酶抑制剂,IC50值在3.5至11.3 nM之间。 了解更多
  18. Talabostat mesylate

    Catalog No. A14080
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    DPP-4 抑制剂
    Talabostat mesylate是一种有效的,非选择性的和口服的二肽基肽酶IV(DPP-IV)抑制剂,Ki为0.18 nM。 了解更多
  19. Abametapir

    Catalog No. A15945
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    metalloproteinase 抑制剂
    ABAMETAPIR是Xeglyze乳液的活性成分。ABAMETAPIR抑制金属蛋白酶;对卵子发育,若虫和成年虱子存活至关重要的生理过程必不可少的酶。 了解更多
  20. MRK 560

    Catalog No. A15304
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    γ-secretase 抑制剂
    MRK 560是一种可用的γ-分泌酶抑制剂,能够显着减少大鼠脑和CSF中的Abeta肽,并证实该大鼠可用于评估γ-分泌酶抑制剂对中枢神经系统Abeta的作用(40)体内水平。 了解更多
  21. Dabigatran ethyl ester

    Catalog No. A15058
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    thrombin 抑制剂
    Dabigatran ethyl ester是一种新兴的口服抗凝剂,是凝血酶活性的直接抑制剂。 了解更多
  22. Dabigatran etexilate mesylate

    Catalog No. A15057
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    direct thrombin 抑制剂
    Dabigatran etexilate mesylate是达比加群的口服活性前药。达比加群是一种可逆的选择性直接凝血酶抑制剂(DTI),Ki值为4.5 nM。 了解更多
  23. Z-FL-COCHO

    Catalog No. A13502
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    Cathepsin S 抑制剂
    Z-FL-COCHO是新型的组织蛋白酶S抑制剂。 了解更多
  24. Lopinavir (ABT-378)

    Catalog No. A10537
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    HIV Protease 抑制剂
    Lopinavir (ABT-378)是HIV蛋白酶的抑制剂。 了解更多
  25. BIBR 953 (Dabigatran, Pradaxa)

    Catalog No. A10138
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    Thrombin 抑制剂
    BIBR 953 (Dabigatran,Pradaxa)是一种高度选择性,可逆且有效的凝血酶抑制剂,可作为前药达比加群酯口服。它在血栓形成的动物模型中显示出抗血栓形成的功效,起效迅速,可预测的药效学反应。 了解更多
  26. BIBR-1048 (Dabigatran etexilate)

    Catalog No. A10139
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    Thrombin 抑制剂
    BIBR-1048 (Dabigatran etexilate)是dabigatran的前体药物,dabigatran是一种有效的、非肽类小分子化合物,可特异地、可逆性地抑制游离的和结合了血凝块的凝血酶。 了解更多

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