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26 个项目
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Ralfinamide mesylate
Catalog No. A22002 Na+ channel blockerRalfinamide mesylate (FCE-26742A mesylate) is an orally available Na+ channel blocker derived from α-aminoamide, with function of suppressing pain. 了解更多 -
Naspm trihydrochloride
Catalog No. A21437 CP-AMPA receptors antagonistNaspm trihydrochloride (1-Naphthylacetyl spermine trihydrochloride), a synthetic analogue of Joro spider toxin, is a calcium permeable AMPA (CP-AMPA) receptors antagonist. 了解更多 -
Ivacaftor hydrate
Catalog No. A15133 CFTR potentiatorIvacaftor hydrate is an orally bioavailable CFTR potentiator, used for cystic fibrosis treatment. 了解更多 -
Ivacaftor benzenesulfonate
Catalog No. A15132 CFTR potentiatorIvacaftor benzenesulfonate is an orally bioavailable CFTR potentiator, used for cystic fibrosis treatment. 了解更多 -
Nav1.7-IN-3
Catalog No. A13626 voltage-gated sodium channel Nav1.7 inhibitorNav1.7-IN-3 is a selective, orally bioavailable voltage-gated sodium channel Nav1.7 inhibitor with an IC50 of 8 nM. Pain relief. Limited CNS penetration. 了解更多 -
Norverapamil hydrochloride
Catalog No. A12249 P-gp inhibitorNorverapamil hydrochloride ((??)-Norverapamil hydrochloride), an N-demethylated metabolite of Verapamil, is a L-type calcium channel blocker and a P-glycoprotein (P-gp) function inhibitor. 了解更多 -
ABT-639 hydrochloride
Catalog No. A12571 T-type Ca2+ channel blockerABT-639 hydrochloride is a novel, peripherally acting, selective T-type Ca2+ channel blocker. 了解更多 -
Ertugliflozin L-pyroglutamic acid
Catalog No. A18054 SGLT inhibitorErtugliflozin pidolate belongs to the class of potent and selective inhibitors of the sodium-dependent glucose cotransporters (SGLT), more specifically the type 2 which is responsible for about 90% of the glucose reabsorption from glomerulus. 了解更多 -
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最新产品
SAR-7334 HCl
Catalog No. A17237 TRPC6 inhibitorSAR7334 is a novel, highly potent and bioavailable inhibitor of TRPC6 channels that opens new opportunities for the investigation of TRPC channel function in vivo. SAR7334 inhibited TRPC6, TRPC3 and TRPC7-mediated Ca(2+) influx into cells with IC50 s of 9.5, 282 and 226 nM, whereas TRPC4 and TRPC5-mediated Ca(2+) entry was not affected. 了解更多 -
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最新产品
YHO-13177
Catalog No. A17127 -
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Cannabichromene
Catalog No. A15497 TRPA1 activatior/TRPM8 blockerCannabichromene是一种主要的非精神植物大麻素，可抑制内源性大麻素失活并激活瞬时受体电位锚蛋白1（TRPA1）。内源性大麻素和TRPA1均可调节肠胃蠕动。 了解更多 -
Retigabine dihydrochloride
Catalog No. A15222 KCNQ channel openerRetigabine dihydrochloride是具有抗惊厥活性的Kv7.2-7.5（KCNQ2-5）神经元钾通道开放剂。 了解更多 -
Ouabain
Catalog No. A12755 -
Retigabine (Ezogabine)
Catalog No. A11922 Retigabine是一种新型的抗痉挛剂，在大范围的惊厥模型具有活性。其发挥活性的机制主要是开放神经元的KCNQ2-5电压门控钾离子通道。 了解更多
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