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搜索结果：“jwh 307”

“jwh 307”的搜索结果

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NNC0640

Catalog No. A18900
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GLP-1R modulator

NNC0640 is a negative allosteric modulator of glucagon-like peptide-1 receptor (GLP-1R). 了解更多

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Metoclopramide hydrochloride hydrate

Catalog No. A18072
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Dopamine D2 antagonist

Metoclopramide hydrochloride hydrate is a dopamine D2 antagonist that is used as an antiemetic. 了解更多

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Bay 59-3074

Catalog No. A16328
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CB1/CB2 receptor 激动剂

Bay 59-3074是一种新型的选择性CB1/CB2受体部分激动剂，对人CB1和CB2受体的Ki值分别为48.3和45.5 nM。了解更多

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Vilanterol trifenatate

Catalog No. A15998
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β2-adrenergic receptor 激动剂

Vilanterol trifenatate是一种长效的β-2激动剂药物，于2013年5月与葛兰素氟替卡松合用，获葛兰素史克（Brax Elmitta）出售为Breo Ellipta，用于治疗慢性阻塞性肺疾病（COPD）。了解更多

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Ponesimod

Catalog No. A13307
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S1P1 receptor modulator

Ponesimod是一种口服活性，选择性鞘氨醇-1-磷酸受体1（S1P1）免疫调节剂，EC50为5.7 nM。了解更多

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Cariprazine hydrochloride

Catalog No. A15036
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D3/D2 Dopamine Receptor 拮抗剂

Cariprazine hydrochloride是一种新型的抗精神病药物，对多巴胺D3（Ki = 0.09 nM）和D2（Ki = 0.5 nM）受体具有高选择性和亲和力，对5-羟色胺5-HT（1A）受体具有中等亲和力。了解更多

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Xylazine HCl

Catalog No. A13434
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Adrenergic Receptor 激动剂

Xylazine hydrochloride是α2A-AR、α2B-AR和α2C-AR的活化剂。了解更多

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Rauwolscine

Catalog No. A13426
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α2-adrenergic receptor 拮抗剂

Rauwolscine是一种天然生物碱，具有选择性和可逆性α2肾上腺素能受体拮抗剂(Ki = 12 nM)。了解更多

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R-121919

Catalog No. A13535
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CRF1 receptor 拮抗剂

R121919是有效的小分子CRF1受体拮抗剂。了解更多

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Eletriptan

Catalog No. A13075
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5-HT1B receptor 激动剂

Eletriptan是一种选择性5-羟色胺1B/1D（5-HT1B）受体激动剂。了解更多

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AMD3100 (Plerixafor)

Catalog No. A13074
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CXCR4 拮抗剂

AMD3100 (Plerixafor)是用于增殖造血干细胞的免疫刺激剂，并且是用于动员造血干细胞进行移植的趋化因子受体-4拮抗剂。了解更多

Product Citations (11)

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- Hitoshi Maeda, .et al. Cell-penetrating albumin enhances the sublingual delivery of antigens through macropinocytosis, Int J Biol Macromol, 2022, Sep 17;221:1439-1452 PMID: 36126807
- Jingying Chen, .et al. Brain vascular damage-induced lymphatic ingrowth is directed by Cxcl12b/Cxcr4a, Development, 2022, Jul 1;149(13) PMID: 35694896
- Narubhorn Ongprakobkul, .et al. Effects of local vs systemic administration of CXCR4 inhibitor AMD3100 on orthodontic tooth movement in rats, Am J Orthod Dentofacial Orthop, 2022, Mar 2;S0889-5406(22)00107-X PMID: 35248418
- Chunliang Liu, .et al. Positive effects of selenium supplementation on selenoprotein S expression and cytokine status in a murine model of acute liver injury, J Trace Elem Med Biol, 2022, Jan 10;71:126927 PMID: 35030482
- Eri Watanabe, .et al. Stromal cell-derived factor 1 (SDF1) attenuates platelet-derived growth factor-B (PDGF-B)-induced vascular remodeling for adipose tissue expansion in obesity, Angiogenesis, 2020, Jul 22 PMID: 32699964
- Alessandra Esposito, .et al. Role of Prx1-expressing skeletal cells and Prx1-expression in fracture repair, Bone, 2020, Jul 3;139:115521 PMID: 32629173
- Kentaro Suzuki, .et al. C-terminal?Cmodifed LY2510924: a versatile scafold for targeting C-X-C chemokine receptor type 4, Sci Rep, 2019, 9: 15284
- Ichimizu S, .et al. Cell-penetrating mechanism of intracellular targeting albumin: Contribution of macropinocytosis induction and endosomal escape, J Control Release, 2019, May 10;304:156-163 PMID: 31082432
- Nan Li, .et al. LPS-induced CXCR7 expression promotes gastric Cancer proliferation and migration via the TLR4/MD-2 pathway, Diagn Pathol, 2019, Jan 12;14(1):3 PMID: 30636642
- Thida W, .et al. The role of conventional antibodies targeting the CD4 binding site and CD4-induced epitopes in the control of HIV-1 CRF01_AE viruses, Biochem Biophys Res Commun, 2018, Nov 20. pii: S0006-291X(18)32477-X PMID: 30470571
- Henry R. Hampton, .et al. Microbe-dependent lymphatic migration of neutrophils modulates lymphocyte proliferation in lymph nodes, Nat Commun, 2015, 6: 7139 PMID: 25972253
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Clemizole

Catalog No. A13073
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H1 histamine receptor 拮抗剂.

Clemizole是H1组胺受体拮抗剂。了解更多

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Terazosin hydrochloride

Catalog No. A11740
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Terazosin hydrochloride是一种选择性α1拮抗剂，用于治疗前列腺肥大(BPH)症状。了解更多

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Azelastine HCl (Allergodil)

Catalog No. A10117
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Azelastine HCl (Allergodil)是有效的第二代选择性组胺拮抗剂（组胺-H1-受体拮抗剂）。了解更多

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