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产品 1 到 50 共 17506个

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  1. Guanosine 5'-triphosphate trisodium salt

    Catalog No. A18283
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    Guanosine 5'-triphosphate trisodium salt (5'-GTP trisodium salt) is an activator of signal transduction of G proteins. 了解更多
  2. 6-Diazo-5-oxo-L-nor-Leucine

    Catalog No. A20846
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    6-Diazo-5-oxo-L-norleucine 是一种从链霉菌中分离出来的抗生素,一种 glutaminase 的拮抗剂对cKGA(肾脏型谷氨酰胺酶)的IC50值约为1 mM。 了解更多
  3. Docosahexaenoic Acid

    Catalog No. A18205
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    Docosahexaenoic Acid (DHA) is an omega-3 fatty acid abundantly present brain and retina. It can be obtained directly from fish oil and maternal milk. 了解更多
  4. Erianin

    Catalog No. A12050
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    Erianin,常用作退烧药和止疼剂,能够抑制吲哚胺-2,3-双加氧酶 (IDO) 诱导的肿瘤血管生成。 了解更多
  5. Corticosterone

    Catalog No. A14269
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    Corticosterone 是一种具有口服活性的,由肾上腺皮质产生的糖皮质激素,在调节边缘系统 (包括海马体、前额叶皮层和杏仁核) 的神经元功能方面起着重要作用。皮质酮可通过 SGK 诱导的 GDI 磷酸化增加 Rab 介导的 AMPAR 膜运输. 了解更多
  6. DL-AP5

    Catalog No. A20527
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    DL-AP5 (2-APV) 是一种竞争性的 NMDA (N-methyl-D-aspartate) 受体拮抗剂。DL-AP5 表现出明显的镇痛活性。DL-AP5 可特异性阻断兔视网膜的通道。 了解更多
  7. Auranofin

    Catalog No. A18996
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    Auranofin is a gold salt classified by the World Health Organization as an antirheumatic agent. It is a gold-thiol complex with anti-inflammatory and immunosuppressive actions. 了解更多
  8. Enocyanin

    Catalog No. A18660
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    anthocyanin extracted from grapes
    Enocyanin is an anthocyanin extracted from grapes. Enocyanin shows inhibitory effect on the leucine aminopeptidase, acid phosphatase, γ-glutamyl transpeptidase and esterase activity. 了解更多
  9. Triphala

    Catalog No. A16067
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    Anti-adipogenic, anti-inflammatory, and anti-neoplastic activities
    Triphala, an Ayurvedic polyherbal formulation comprising of equiproportional fruit parts of Terminalia chebula, Terminalia bellerica, and Phyllanthus emblica. Triphala inhibits NF-κB activation. Triphala exerts antifungal action. Anti-adipogenic, anti-inflammatory, and anti-neoplastic activities. 了解更多
  10. Adenosine deaminase

    Catalog No. A19330
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    Adenosine deaminase is an enzyme that catalyzes the irreversible deamination of adenosine and 2'-deoxyadenosine to inosine and 2'-deoxyinosine, respectively. 了解更多
  11. Thrombin

    Catalog No. A18861
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    digest GST-tagged proteins
    Thrombin is a trypsin-like allosteric serine protease. Thrombin enables site-specific cleavage of fusion proteins with an accessible Thrombin recognition sequence and can be used to digest GST-tagged proteins. 了解更多
  12. Angiotensin III

    Catalog No. A18943
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    angiotensin 1 (AT1) and AT2 receptor agonist
    Angiotensin III is an angiotensin 1 (AT1) and AT2 receptor agonist. 了解更多
  13. Melanin

    Catalog No. A19576
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    unique pigment
    Melanin is a unique pigment with myriad functions. It is multifunctional, providing defense against environmental stresses such as ultraviolet (UV) light, oxidizing agents and ionizing radiation. 了解更多
  14. Pertussis Toxin

    Catalog No. A19356
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    protein-based AB5-type exotoxin
    Pertussis Toxin is a protein-based AB5-type exotoxin produced by the bacterium Bordetella pertussis, which causes whooping cough. 了解更多
  15. Xylan

    Catalog No. A19997
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    Xylan represents the main hemicellulose component in the secondary plant cell walls of flowering plants. Xylan is a polysaccharide made from units of xylose and contains predominantly β-D-xylose units linked as in cellulose. 了解更多
  16. Lignine

    Catalog No. A20324
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    Lignine (Lignin) is a complex organic polymer, which plays an important role in plant cell wall structure. 了解更多
  17. Calf thymus DNA

    Catalog No. A20155
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    Calf thymus DNA (DNA from calf thymus) is high quality double-stranded template DNA isolated from the thymus of male and female calves. 了解更多
  18. Chitosan oligosaccharide

    Catalog No. A20304
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    Chitosan oligosaccharide (COS) is an oligomer of β-(1??4)-linked D-glucosamine. Chitosan oligosaccharide (COS) activates AMPK and inhibits inflammatory signaling pathways including NF-κB and MAPK pathways. 了解更多
  19. Saponins

    Catalog No. A16691
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    Saponins are a class of chemical compounds of glycosides found in particular abundance in various plant species. In plants, saponins may serve as anti-feedants, and to protect the plant against microbes and fungi. 了解更多
  20. Hypotaurine

    Catalog No. A20590
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    Hypotaurine (2-aminoethanesulfinic acid), an intermediate in taurine biosynthesis from cysteine in astrocytes, is an endogenous inhibitory amino acid of the glycine receptor. 了解更多
  21. Calcium polystyrene sulfonate

    Catalog No. A18233
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    used to treat hyperkalemia in patients with chronic kidney disease (CKD)
    Calcium polystyrene sulfonate is an ion-exchange resin used for reducing blood levels of potassium. Calcium polystyrene sulfonate is used to treat hyperkalemia in patients with chronic kidney disease (CKD). 了解更多
  22. Hyaluronidase

    Catalog No. A18232
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    local anesthetic additive
    Hyaluronidase (Hyaluronate 4-glycanohydrolase; Hyaluronoglucosaminidase) is a naturally occurring enzyme that depolymerizes hyaluronic acid by cleavage of glycosidic bonds and has been used as a local anesthetic additive. 了解更多
  23. Avelumab

    Catalog No. A18234
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    PD-1/PD-L1
    Avelumab is a fully human IgG1 anti-PD-L1 monoclonal antibody with potential antibody-dependent cell-mediated cytotoxicity. 了解更多
  24. HM-43239

    Catalog No. A20826
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    FLT3 inhibitor
    HM-43239 is a Novel Potent Small Molecule FLT3 Inhibitor, in Acute Myeloid Leukemia (AML) with FMS-like Tyrosine Kinase 3 (FLT3) Mutations 了解更多
  25. Cinnamylamine

    Catalog No. A20835
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    Cinnamylamine can be used for the preparation of Tranylcypromine, a drug that acts as a nonselective and irreversible inhibitor of the enzyme monoamine oxidase (MAO), and is used as an antidepressant and anxiolytic agent. 了解更多
  26. IRL-1620

    Catalog No. A21080
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    endothelin receptor type B (ETB) agonist
    IRL-1620 is a potent and selective endothelin receptor type B (ETB) agonist with a Ki of 16 pM. 了解更多
  27. Peptide 401

    Catalog No. A13913
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    Peptide 401, a potent mast cell degranulating factor from bee venom, suppresses the increased vascular permeability due to intradermal injection of various smooth muscle spasmogens (histamine, and 5-HT). 了解更多
  28. Exendin-4

    Catalog No. A21580
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    glucagon-like peptide-1 receptor agonist
    Exendin-4 (Exenatide), a 39 amino acid peptide, is a long-acting glucagon-like peptide-1 receptor agonist with an IC50 of 3.22 nM. 了解更多
  29. BI-4020

    Catalog No. A22046
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    EGFR inhibitor
    BI-4020 is an orally active, non-covalent EGFR inhibitor with IC50 of 0.6 nM and 0.2 nM for EGFR. 了解更多
  30. SR-717

    Catalog No. A22048
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    non-nucleotide STING agonist
    SR-717 is a non-nucleotide STING agonist with EC50s of 2.1 μM and 2.2 μM in ISG-THP1 (WT) and ISG-THP1 cGAS KO (cGAS KO) cell lines, respectively. 了解更多
  31. Apilimod mesylate

    Catalog No. A22049
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    IL-12/IL-23 inhibitor
    Apilimod (STA 5326) mesylate is a potent IL-12/IL-23 inhibitor, and strongly inhibits IL-12 with IC50s of 1 nM and 2 nM, in IFN-γ/SAC-stimulated human PBMCs and SAC-treated monkey PBMCs, respectively. 了解更多
  32. DT2216

    Catalog No. A22050
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    BCL-XL degrader
    DT2216 is a potent and selective BCL-XL degrader based on PROTAC technology. 了解更多
  33. Sulopenem

    Catalog No. A22051
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    beta-lactamase inhibitor
    Sulopenem (CP-70429) is an orally active, potent inhibitor of beta-lactamase. Sulopenem is a parenteral penem antibiotic with broad-spectrum activities against Gram-positive and Gram-negative bacteria. 了解更多
  34. BMVC-8C3O

    Catalog No. A22052
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    DNA G-quadruplexe (G4) ligand
    BMVC-8C3O is a DNA G-quadruplexe (G4) ligand which can induce topological conversion of non-parallel to parallel forms in human telomeric DNA G4s. 了解更多
  35. XP-59

    Catalog No. A22053
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    SARS-CoV Mpro inhibitor
    XP-59 is a potent inhibitor of the SARS-CoV Mpro, with a Ki of 0.1 μM. 了解更多
  36. LC3-mHTT-IN-AN1

    Catalog No. A22054
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    mHTT-LC3 linker compound
    LC3-mHTT-IN-AN1 (Compound AN1) is a mHTT-LC3 linker compound, which interacts with both mutant huntingtin protein (mHTT) and LC3B but not with wtHTT or irrelevant control proteins. 了解更多
  37. APX-115 free base

    Catalog No. A22055
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    pan NADPH oxidase (Nox) inhibitor
    APX-115 free base (Ewha-18278 free base) is a potent, orally active pan NADPH oxidase (Nox) inhibitor with Ki values of 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2 and Nox4, respectively. 了解更多
  38. Mizagliflozin

    Catalog No. A22056
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    SGLT1 inhibitor
    Mizagliflozin (DSP-3235 free base) is a potent, orally active and selective SGLT1 inhibitor, with a Ki of 27 nM for human SGLT1. 了解更多
  39. TLR4-IN-C34

    Catalog No. A22057
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    TLR4 inhibitor
    TLR4-IN-C34 is an orally active TLR4 inhibitor and reduces systemic inflammation in models of endotoxemia and necrotizing enterocolitis. 了解更多
  40. DIMBOA

    Catalog No. A22058
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    antifungal agent
    Dimboa is an antifungal agent used in crops. 了解更多
  41. H-β-Ala-AMC TFA

    Catalog No. A22059
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    substrate for aminopeptidase
    H-β-Ala-AMC TFA is a substrate for aminopeptidase. 了解更多
  42. PF-04745637

    Catalog No. A22060
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    TRPV1 antagonist
    PF-04745637 is a TRPV1 antagonist. 了解更多
  43. BMS-1001

    Catalog No. A22061
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    PD-1/PD-L1 interaction inhibitor
    BMS-1001 is a potent inhibitor of PD-1/PD-L1 interaction with EC50 of 253 nM. 了解更多
  44. KGA-2727

    Catalog No. A22062
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    SGLT1 inhibitor
    KGA-2727 is a first selective, high-affinity and orally active SGLT1 inhibitor with Kis of 97.4 nM and 43.5 nM for human and rat SGLT1, respectively. 了解更多
  45. Filastatin

    Catalog No. A22063
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    Candida albicans filamentation inhibitor
    Filastatin is a long-lasting inhibitor of Candida albicans filamentation. Filastatin inhibits adhesion by multiple pathogenic Candida species with an IC50 of ~3 μM in the GFP-based adhesion assay. 了解更多
  46. Neuraminidase-IN-1

    Catalog No. A22065
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    neuraminidase inhibitor
    Neuraminidase-IN-1 is a neuraminidase inhibitor, with an IC50 of 0.21 μM. Neuraminidase-IN-1 has excellent activity against H1N1 influenza virus. 了解更多
  47. 9-ING-41

    Catalog No. A22066
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    glycogen synthase kinase-3β (GSK-3β) inhibitor
    9-ING-41 is a maleimide-based ATP-competitive and selective glycogen synthase kinase-3β (GSK-3β) inhibitor with an IC50 of 0.71 μM. 了解更多
  48. BAY 2416964

    Catalog No. A22067
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    aryl hydrocarbon receptor (AHR) antagonist
    BAY 2416964 is a potent and orally active aryl hydrocarbon receptor (AHR) antagonist extracted from patent WO2018146010A1, example 192, has an IC50 of 341 nM. BAY 2416964 has the potential for solid tumors treatment. 了解更多
  49. GSK046

    Catalog No. A22068
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    BD2 bromodomain inhibitor of the BET proteins
    GSK046 (iBET-BD2) is a potent, selective and orally active BD2 bromodomain inhibitor of the BET proteins, with IC50s of 264 nM (BRD2 BD2), 98 nM (BRD3 BD2), 49 nM (BRD4 BD2) and 214 nM (BRDT BD2), respectively. 了解更多
  50. DiZPK

    Catalog No. A22069
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    photocrosslinker
    DiZPK is a photocrosslinker for identifying direct protein-protein interactions in living prokaryotic and eukaryotic cells. 了解更多

产品 1 到 50 共 17506个

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