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搜索结果：“391210-10-9”

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PD0325901

Catalog No. A10256
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MEK 抑制剂

PD0325901是一种选择性的，非ATP竞争性MEK抑制剂，无细胞试验中IC50为0.33 nM，对ERK1和ERK2磷酸化抑制作用比CI-1040强500倍左右。了解更多

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- Jan Langkabel, .et al. Induction of peri-implantation stage synthetic embryos using reprogramming paradigms in ESCs, bioRxiv, 2021, January 25
- Ryan Clarke, .et al. Sequential Activation of Guide RNAs to Enable Successive CRISPR-Cas9 Activities, Mol Cell, 2021, Jan 21;81(2):226-238.e5 PMID: 33378644
- Tzeng SF, .et al. O-Glycosylation-mediated signaling circuit drives metastatic castration-resistant prostate cancer, FASEB J, 2018, Jun 15:fj201800687 PMID: 29906246
- Fukumoto S, .et al. Synergistic anti-proliferative effects of mTOR and MEK inhibitors in high-grade chondrosarcoma cell line OUMS-27, Acta Histochem, 2018, Feb;120(2):142-150 PMID: 29397960
- Yoshiteru Yano, .et al. Non-neural and cardiac differentiating properties of Tbx6-expressing mouse embryonic stem cells, Regenerative Therapy, 2016, 3 (2016) 1-6

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