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￥ 0.00 “ADM Hydrochloride”的搜索结果
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Alectinib Hydrochloride
Catalog No. A18000 ALK inhibitorAlectinib Hydrochloride (CH5424802 Hydrochloride; RO5424802 Hydrochloride; AF-802 Hydrochloride) is a potent, selective, and orally available ALK inhibitor with an IC50 of 1.9 nM and a Kd value of 2.4 nM (in an ATP-competitive manner), and also inhibits ALK F1174L and ALK R1275Q with IC50s of 1 nM and 3.5 nM, respectively. 了解更多 -
Defactinib hydrochloride
Catalog No. A22003 FAK inhibitorDefactinib hydrochloride (VS-6063 hydrochloride; PF 04554878 hydrochloride) is a novel FAK inhibitor, which inhibits FAK phosphorylation at the Tyr397 site in a time- and dose-dependent manner. 了解更多 -
Nevanimibe hydrochloride
Catalog No. A21767 ACAT1 inhibitorNevanimibe hydrochloride (PD-132301 hydrochloride; ATR101 hydrochloride) is a selective and potent acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) inhibitor with an EC50 of 9 nM. 了解更多 -
Amsacrine hydrochloride
Catalog No. A17707 antineoplastic agentAmsacrine hydrochloride (m-AMSA hydrochloride; acridinyl anisidide hydrochloride) is an inhibitor of topoisomerase II, and acts as an antineoplastic agent which can intercalates into the DNA of tumor cells. 了解更多 -
GAP-134 Hydrochloride
Catalog No. A15092 Gap-junction modifierGAP-134 Hydrochloride是一种小的修饰二肽，已被确定为具有口服生物利用度的有效且选择性的第二代间隙连接修饰剂。 了解更多 -
NS-3-008 hydrochloride
Catalog No. A22651 transcriptional inhibitor of G0/G1 switch 2NS-3-008 hydrochloride is an orally active transcriptional inhibitor of G0/G1 switch 2 (G0s2) with an IC50 of 2.25 μM. NS-3-008 hydrochloride can be used for chronic kidney disease. 了解更多 -
Bisindolylmaleimide X hydrochloride
Catalog No. A22010 PKC inhibitorBisindolylmaleimide X hydrochloride (BIM-X hydrochloride) is a potent and selective protein kinase C (PKC) inhibitor. 了解更多 -
Tebanicline hydrochloride
Catalog No. A21918 nAChR modulatorTebanicline hydrochloride (ABT594 hydrochloride) is a nAChR modulator with potent, orally effective analgesic activity. 了解更多 -
Aliskiren D6 Hydrochloride
Catalog No. A21913 direct renin inhibitorAliskiren D6 Hydrochloride (CGP 60536 D6 Hydrochloride) is is deuterium labeled Aliskiren, which is a direct renin inhibitor with IC50 of 1.5 nM. 了解更多 -
Gaboxadol hydrochloride
Catalog No. A21730 GABAA receptors agonistGaboxadol hydrochloride (Lu 02-030 hydrochloride) is a selective agonist at GABAA receptors that contain α4-δ subunits, and has anxiolytic and sedative effects. 了解更多 -
Raxatrigine hydrochloride
Catalog No. A21645 Nav1.7 sodium channel inhibitorRaxatrigine hydrochloride (GSK-1014802 hydrochloride) is a novel small molecule state-dependent sodium channel blocker; Nav1.7 sodium channel inhibitor. 了解更多 -
Norepinephrine hydrochloride
Catalog No. A21605 β1-selective adrenergic receptor agonistNorepinephrine hydrochloride (Levarterenol hydrochloride; L-Noradrenaline hydrochloride) is a β1-selective adrenergic receptor agonist with EC50 of 5.37 μM. 了解更多 -
Amuvatinib hydrochloride
Catalog No. A21503 multi-targeted tyrosine kinase inhibitorAmuvatinib hydrochloride (MP470 hydrochloride) is an orally bioavailable multi-targeted tyrosine kinase inhibitor with potent activity against mutant c-Kit, PDGFRα, Flt3, c-Met and c-Ret. 了解更多 -
EIPA hydrochloride
Catalog No. A21441 TRPP3 channel inhibitorEIPA hydrochloride (L593754 hydrochloride) is a TRPP3 channel inhibitor with an IC50 of 10.5 μM. EIPA also inhibits Na+/H+-exchanger (NHE) and macropinocytosis. 了解更多 -
N-Desmethyl Clomipramine D3 hydrochloride
Catalog No. A21369 N-Desmethyl Clomipramine D3 hydrochloride is the deuterium labeled N-Desmethyl Clomipramine. N-Desmethyl Clomipramine hydrochloride (Desmethylclomipramine hydrochloride) is a primary plasma N-desmethyl metabolite of Clomipramine'. 了解更多 -
Galidesivir hydrochloride
Catalog No. A20930 RdRp inhibitorGalidesivir hydrochloride (BCX 4430 hydrochloride) is a viral RNA-dependent RNA polymerase (RdRp) inhibitor; demonstrated broad-spectrum activity in multiple viruses and a favorable preliminary preclinical safety profile. 了解更多 -
Norverapamil hydrochloride
Catalog No. A12249 P-gp inhibitorNorverapamil hydrochloride ((??)-Norverapamil hydrochloride), an N-demethylated metabolite of Verapamil, is a L-type calcium channel blocker and a P-glycoprotein (P-gp) function inhibitor. 了解更多 -
Alosetron (Hydrochloride(1:X))
Catalog No. A11309 Serotonin 5HT3-receptor antagonistAlosetron Hydrochloride(1:X) (GR 68755 Hydrochloride(1:X)) is a Serotonin 5HT3-receptor antagonist that is used in treatment of irritable bowel syndrome. 了解更多 -
TGR-1202 hydrochloride (Umbralisib HCl)
Catalog No. A16278 PI3Kδ 抑制剂TGR-1202 hydrochloride是一种口服的下一代PI3Kδ抑制剂，在基于酶和细胞的测定中抑制PI3Kδ活性，IC50和EC50值分别为22.2和24.3 nM。 了解更多 -
Ribociclib hydrochloride
Catalog No. A22303 CDK4/6 inhibitorRibociclib hydrochloride (LEE011 hydrochloride) is a highly specific CDK4/6 inhibitor with IC50 values of 10 nM and 39 nM, respectively, 了解更多 -
AG-1478 hydrochloride
Catalog No. A22262 EGFR tyrosine kinase inhibitorAG-1478 hydrochloride (Tyrphostin AG-1478 hydrochloride) is a selective EGFR tyrosine kinase inhibitor with IC50 of 3 nM. 了解更多 -
Tirabrutinib hydrochloride
Catalog No. A22375 BTK inhibitorTirabrutinib (ONO-4059) hydrochloride is a selective and novel inhibitor of BTK with IC50 2.2 nm, Tirabrutinib binds to BTK within B cells, thereby preventing B-cell receptor signaling and impeding B-cell development. 了解更多 -
ZM323881 hydrochloride
Catalog No. A22392 VEGFR2 inhibitorZM323881 hydrochloride is a potent and selective VEGFR2 inhibitor with an IC50 of less than 2 nM. 了解更多 -
Ligustrazine hydrochloride
Catalog No. A22455 antioxidant agentLigustrazine hydrochloride (Tetramethylpyrazine, Tetrapyrazine) is a chemical compound found in natto and in fermented cocoa beans with anti-inflammation, antioxidant, antiplatelet, and antiapoptosis activities. 了解更多 -
Tetrahydropalmatine hydrochloride
Catalog No. A22456 analgesic agentTetrahydropalmatine hydrochloride (DL-Tetrahydropalmatine hydrochloride), an active component isolated from corydalis, possesses analgesic effects. Tetrahydropalmatine hydrochloride acts through inhibition of amygdaloid release of dopamine to inhibit an epileptic attack in rats. 了解更多 -
(S,R,S)-AHPC-PEG3-NH2 hydrochloride
Catalog No. A20202 E3 ligase ligand-linker conjugate(S,R,S)-AHPC-PEG3-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 3-unit PEG linker used in PROTAC technology. 了解更多 -
(S,R,S)-AHPC-PEG2-NH2 hydrochloride
Catalog No. A20191 E3 ligase ligand-linker conjugate(S,R,S)-AHPC-PEG2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker used in PROTAC technology. 了解更多 -
(S,R,S)-AHPC-PEG4-NH2 hydrochloride
Catalog No. A20180 E3 ligase ligand-linker conjugate(S,R,S)-AHPC-PEG4-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 4-unit PEG linker used in PROTAC technology. 了解更多 -
DSP-4 hydrochloride
Catalog No. A19539 DSP-4 hydrochloride (Neurotoxin DSP 4 hydrochloride) is a highly selective neurotoxin and readily passes the blood-brain barrier with neurotoxic effects on noradrenergic neurons of adult and developing rats, can be used for the temporary selective degradation of the central and peripheral noradrenergic neurons, mainly those from the locus coeruleus (LC). 了解更多 -
Barnidipine hydrochloride
Catalog No. A19280 L-type calcium antagonistBarnidipine hydrochloride (Mepirodipine hydrochloride) is an L-type calcium antagonist (CaA) with high affinity for [3H] initrendipine binding sites (Ki=0.21 nmol/l), has selective action against CaA receptors. 了解更多 -
Tecalcet Hydrochloride
Catalog No. A21404 Tecalcet Hydrochloride (R 568 Hydrochloride), an orally active calcimimetic compound, allosterically and positively modulates the calcium-sensing receptor (CaSR). 了解更多 -
Ombrabulin hydrochloride
Catalog No. A21040 Ombrabulin hydrochloride is a derivative of CA-4 phosphate, which is known to exhibit antivascular effects through selective disruption of the tubulin cytoskeleton of endothelial cells. 了解更多 -
Olcegepant hydrochloride
Catalog No. A21900 CGRP1 receptor antagonistOlcegepant hydrochloride is the first potent and selective non-peptide antagonist of the calcitonin gene-related peptide 1 (CGRP1) receptor with IC50 of 0.03 nM and with a Ki of 14.4 pM for human CGRP. 了解更多 -
BX471 hydrochloride
Catalog No. A21886 non-peptide CCR1 antagonistBX471 hydrochloride (ZK-811752 hydrochloride) is a potent, selective non-peptide CCR1 antagonist with Ki of 1 nM for human CCR1, and exhibits 250-fold selectivity for CCR1 over CCR2, CCR5 and CXCR4. 了解更多 -
Btk inhibitor 1 R enantiomer hydrochloride
Catalog No. A21865 BTK inhibitorBtk inhibitor 1 R enantiomer hydrochloride (Ibrutinib analog hydrochloride) (Compound 14) is a covalent and irreversible Bruton??s tyrosine kinase (BTK) inhibitor and can be used in synthesis of Ibrutinib and ibrutinib-based activity-based probes (ABPs). 了解更多 -
Eniporide hydrochloride
Catalog No. A21864 Na+/H+ exchange inhibitorEniporide hydrochloride (EMD-96785 hydrochloride) is a potent Na+/H+ exchange inhibitor. 了解更多 -
BCI hydrochloride
Catalog No. A21797 dual specificity phosphatase inhibitorBCI hydrochloride ((E)-BCI hydrochloride) is an allosteric inhibitor of dual specificity phosphatase (DUSP). 了解更多 -
Pyridostatin hydrochloride
Catalog No. A21727 G-quadruplexe stabilizerPyridostatin hydrochloride (RR82 hydrochloride) is a G-quadruplexe stabilizer, with a Kd of 490 nM. 了解更多 -
Ensartinib hydrochloride
Catalog No. A21719 ALK/MET inhibitorEnsartinib hydrochloride (X-396 hydrochloride) is a potent and dual ALK/MET inhibitor with IC50s of <0.4 nM and 0.74 nM, respectively. 了解更多 -
Dasotraline hydrochloride
Catalog No. A21684 triple reuptake inhibitorDasotraline hydrochloride (SEP-225289 hydrochloride) is a triple reuptake inhibitor that blocks dopamine, norepinephrine, and serotonin transporters with IC50 values of 4, 6, and 11 nM, respectively. 了解更多 -
Pardoprunox hydrochloride
Catalog No. A21624 partial dopamine D2 and D3 receptor agonistPardoprunox hydrochloride is a novel partial dopamine D2 and D3 receptor agonist and serotonin 5-HT1A receptor agonist, D2 (pKi = 8.1) and D3 receptor (pKi = 8.6) partial agonist and 5-HT1A receptor (pKi = 8.5) full agonist. 了解更多 -
Verubulin hydrochloride
Catalog No. A21607 microtubule-disrupting agentVerubulin hydrochloride (MPC-6827 hydrochloride) is a blood brain barrier permeable microtubule-disrupting agent, with potent and broad-spectrum in vitro and in vivo cytotoxic activities. 了解更多 -
Omadacycline hydrochloride
Catalog No. A21540 Omadacycline hydrochloride is novel, aminomethyl tetracycline antibiotic being developed for the treatment of community-acquired bacterial infections. The ED50 for Escherichia coli is 2.02 mg/kg. 了解更多 -
Varenicline Hydrochloride
Catalog No. A21539 α4β2 nAChR partial agonistVarenicline Hydrochloride (CP 526555 hydrochloride) is a high affinity, selective α4β2 nicotine acetylcholine receptor (nAChR) partial agonist and full α7 nAChR agonist. 了解更多 -
SB 203580 hydrochloride
Catalog No. A21526 p38 MAPK inhibitorSB 203580 hydrochloride (RWJ 64809 hydrochloride) is a widely used p38 MAPK inhibitor. 了解更多 -
BMS-1166 hydrochloride
Catalog No. A21481 PD-1/PD-L1 interaction inhibitorBMS-1166 hydrochloride is a potent PD-1/PD-L1 interaction inhibitor with an IC50 of 1.4 nM. BMS-1166 antagonizes the inhibitory effect of PD-1/PD-L1 immune checkpoint on T cell activation. 了解更多 -
(S,R,S)-AHPC hydrochloride
Catalog No. A21414 (S,R,S)-AHPC hydrochloride (MDK7526 hydrochloride) is the VH032-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein. 了解更多 -
Ezatiostat hydrochloride
Catalog No. A21222 glutathione analog inhibitorEzatiostat hydrochloride (TER199;TLK199 hydrochloride) is a glutathione analog inhibitor of glutathione S-transferase P1-1 (GSTP1-1). 了解更多 -
Diclofensine hydrochloride
Catalog No. A20923 monoamine reuptake inhibitorDiclofensine hydrochloride (Ro-8-4650 hydrochloride) is a potent inhibitor of monoamine reuptake, blocking the uptake of dopamine, noradrenaline, and serotonin by rat brain synaptosomes with IC50 values of 0.74, 2.3, and 3.7 nM, respectively. 了解更多 -
Efonidipine hydrochloride monoethanolate
Catalog No. A18030 dual T-type and L-type calcium channel blockerEfonidipine hydrochloride monoethanolate (NZ-105 hydrochloride monoethanolate) is a dual T-type and L-type calcium channel blocker (CCB). 了解更多
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