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(Rac)-AZD 6482
Catalog No. A20629 p110β inhibitorRac)-AZD 6482 ((Rac)-KIN-193) is a less active racemate of AZD 6482. AZD 6482 is a potent and selective p110β inhibitor with an IC50 of 0.69 nM. 了解更多 -
AZD-5991 S-enantiomer
Catalog No. A21361 Mcl-1 inhibitorAZD-5991 S-enantiomer is the less active enantiomer of AZD-5991. AZD-5991 S-enantiomer is a Mcl-1 inhibitor with an IC50 of 6.3 μM in FRET assay and a Kd of 0.98 μM in surface plasmon resonance (SPR) assay. 了解更多 -
AZD-5991 Racemate
Catalog No. A21357 Mcl-1 inhibitorAZD-5991 Racemate is the racemate of AZD-5991. AZD-5991 Racemate is a Mcl-1 inhibitor with an IC50 of <3 nM in FRET assay. 了解更多 -
AZD 9272
Catalog No. A19738 -
AZD-9291 (Osimertinib)
Catalog No. A13681 EGFR 抑制剂AZD-9291 (Osimertinib)是第三代EGFR抑制剂，在临床前研究中显示出希望，并为已对现有EGFR抑制剂产生耐药性的晚期肺癌患者提供了希望。 了解更多 -
AZD-2461
Catalog No. A12393 -
AZD-4635 (HTL1071)
Catalog No. A16820 -
AZD-5069
Catalog No. A15941 -
Volitinib (Savolitinib, AZD-6094)
Catalog No. A14419 -
Osimertinib dimesylate
Catalog No. A18243 EGFR inhibitorOsimertinib dimesylate (AZD-9291 dimesylate) is an irreversible and mutant selective EGFR inhibitor with IC50s of 12 and 1 nM against EGFRL858R and EGFRL858R/T790M, respectively. 了解更多 -
Cediranib maleate
Catalog No. A21857 VEGFR inhibitorCediranib maleate (AZD-2171 maleate) is a highly potent, orally available VEGFR inhibitor with IC50s of <1, <3, 5, 5, 36, 2 nM for Flt1, KDR, Flt4, PDGFRα, PDGFRβ, c-Kit, respectively. 了解更多 -
Ispronicline (TC-1734, AZD-3480)
Catalog No. A14183 nAChR 激动剂Ispronicline (TC-1734,AZD-3480)是神经元烟碱乙酰胆碱受体部分激动剂。Ispronicline是亚型选择性的，主要与a4b2亚型结合。它具有抗抑郁、益智和神经保护作用。 了解更多 -
AZD6482 (S-isomer)
Catalog No. A22606 PI3Kβ inhibitorAZD6482 (S-isomer), CAS#1173900-37-2, is an isomer of AZD6482 (MedKoo Cat#406268) with S-configuration. AZD6482 is a potent, selective and ATP competitive PI3Kβ inhibitor (IC(50) 0.01 μm). 了解更多 -
Verdiperstat (AZD3241)
Catalog No. A22041 MPO inhibitorVerdiperstat (AZD3241) is a selective, irreversible and orally active myeloperoxidase (MPO) inhibitor, with an IC50 of 630 nM, and can be used in the research of neurodegenerative brain disorders. 了解更多 -
Zoliflodacin
Catalog No. A22032 DNA gyrase/topoisomerase inhibitorZoliflodacin (ETX0914;AZD0914) is a novel spiropyrimidinetrione bacterial DNA gyrase/topoisomerase inhibitor. 了解更多 -
Linaprazan
Catalog No. A20526 Linaprazan (AZD0865) inhibits gastric H+,K+-ATPase by K+-competitive binding. (IC50: 1.0 ± 0.2 μM) It is a acid-suppressing agents with rapid onset of action and potent acid inhibition. 了解更多 -
Lanicemine
Catalog No. A19339 NMDA channel blockerLanicemine (AZD6765) is a low-trapping NMDA channel blocker with a binding (Ki) of 0.56-2.1?μM. 了解更多 -
Elobixibat
Catalog No. A20984 (IBAT inhibitorElobixibat is a potent ileal bile acid transporter (IBAT) inhibitor with IC50 values of 0.53 ?? 0.17 nM, 0.13 ?? 0.03 nM, and 5.8 ?? 1.6 nM for human IBAT, mouse IBAT, and canine IBAT. 了解更多 -
AZD5153 6-Hydroxy-2-naphthoic acid
Catalog No. A21852 BET/BRD4 bromodomain inhibitorAZD5153 6-Hydroxy-2-naphthoic acid is the 6-Hydroxy-2-naphthoic acid of AZD5153. AZD5153 is a potent, selective, and orally available BET/BRD4 bromodomain inhibitor; disrupts BRD4 with an IC50 of 1.7 nM. 了解更多 -
AZD9496 maleate
Catalog No. A21726 estrogen receptor (ERα) antagonistAZD9496 maleate is a potent and selective estrogen receptor (ERα) antagonist with IC50 of 0.28 nM. AZD9496 maleate is an orally bioavailable selective oestrogen receptor degrader (SERD). 了解更多 -
AZD3839 free base
Catalog No. A21606 BACE1 inhibitorAZD3839 (free base) is a potent and selective BACE1 inhibitor with IC50 of 23.6 uM, about 14-fold selectivity over BACE2, also a β-secretase enzyme inhibitor. 了解更多 -
Lanabecestat
Catalog No. A12282 BACE1 inhibitorLanabecestat (AZD3293) is a potent, highly permeable, orally active and blood-brain barrier penetrating BACE1 inhibitor with a Ki of 0.4 nM. 了解更多 -
AZD2906
Catalog No. A18936 glucocorticoid receptor agonistAZD2906 is a selective glucocorticoid receptor (GR) agonist, increases micronucleated immature erythrocytes in the bone marrow of rats. AZD2906 shows IC50s of 2.2, 0.3, 41.6 and 7.5 nM at GR in human, rat PBMC and human, rat whole blood, respectively. 了解更多 -
AZD3229 Tosylate
Catalog No. A16867 -
AZD1208 HCl
Catalog No. A16927
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