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  1. Docosahexaenoic Acid

    Catalog No. A18205
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    Docosahexaenoic Acid (DHA) is an omega-3 fatty acid abundantly present brain and retina. It can be obtained directly from fish oil and maternal milk. 了解更多
  2. Triphala

    Catalog No. A16067
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    Anti-adipogenic, anti-inflammatory, and anti-neoplastic activities
    Triphala, an Ayurvedic polyherbal formulation comprising of equiproportional fruit parts of Terminalia chebula, Terminalia bellerica, and Phyllanthus emblica. Triphala inhibits NF-κB activation. Triphala exerts antifungal action. Anti-adipogenic, anti-inflammatory, and anti-neoplastic activities. 了解更多
  3. Adenosine deaminase

    Catalog No. A19330
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    Adenosine deaminase is an enzyme that catalyzes the irreversible deamination of adenosine and 2'-deoxyadenosine to inosine and 2'-deoxyinosine, respectively. 了解更多
  4. Xylan

    Catalog No. A19997
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    Xylan represents the main hemicellulose component in the secondary plant cell walls of flowering plants. Xylan is a polysaccharide made from units of xylose and contains predominantly β-D-xylose units linked as in cellulose. 了解更多
  5. Lignine

    Catalog No. A20324
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    Lignine (Lignin) is a complex organic polymer, which plays an important role in plant cell wall structure. 了解更多
  6. Saponins

    Catalog No. A16691
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    Saponins are a class of chemical compounds of glycosides found in particular abundance in various plant species. In plants, saponins may serve as anti-feedants, and to protect the plant against microbes and fungi. 了解更多
  7. Hypotaurine

    Catalog No. A20590
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    Hypotaurine (2-aminoethanesulfinic acid), an intermediate in taurine biosynthesis from cysteine in astrocytes, is an endogenous inhibitory amino acid of the glycine receptor. 了解更多
  8. Calcium polystyrene sulfonate

    Catalog No. A18233
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    used to treat hyperkalemia in patients with chronic kidney disease (CKD)
    Calcium polystyrene sulfonate is an ion-exchange resin used for reducing blood levels of potassium. Calcium polystyrene sulfonate is used to treat hyperkalemia in patients with chronic kidney disease (CKD). 了解更多
  9. Hyaluronidase

    Catalog No. A18232
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    local anesthetic additive
    Hyaluronidase (Hyaluronate 4-glycanohydrolase; Hyaluronoglucosaminidase) is a naturally occurring enzyme that depolymerizes hyaluronic acid by cleavage of glycosidic bonds and has been used as a local anesthetic additive. 了解更多
  10. Avelumab

    Catalog No. A18234
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    PD-1/PD-L1
    Avelumab is a fully human IgG1 anti-PD-L1 monoclonal antibody with potential antibody-dependent cell-mediated cytotoxicity. 了解更多
  11. Cinnamylamine

    Catalog No. A20835
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    Cinnamylamine can be used for the preparation of Tranylcypromine, a drug that acts as a nonselective and irreversible inhibitor of the enzyme monoamine oxidase (MAO), and is used as an antidepressant and anxiolytic agent. 了解更多
  12. BI-4020

    Catalog No. A22046
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    EGFR inhibitor
    BI-4020 is an orally active, non-covalent EGFR inhibitor with IC50 of 0.6 nM and 0.2 nM for EGFR. 了解更多
  13. SR-717

    Catalog No. A22048
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    non-nucleotide STING agonist
    SR-717 is a non-nucleotide STING agonist with EC50s of 2.1 μM and 2.2 μM in ISG-THP1 (WT) and ISG-THP1 cGAS KO (cGAS KO) cell lines, respectively. 了解更多
  14. Apilimod mesylate

    Catalog No. A22049
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    IL-12/IL-23 inhibitor
    Apilimod (STA 5326) mesylate is a potent IL-12/IL-23 inhibitor, and strongly inhibits IL-12 with IC50s of 1 nM and 2 nM, in IFN-γ/SAC-stimulated human PBMCs and SAC-treated monkey PBMCs, respectively. 了解更多
  15. Sulopenem

    Catalog No. A22051
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    beta-lactamase inhibitor
    Sulopenem (CP-70429) is an orally active, potent inhibitor of beta-lactamase. Sulopenem is a parenteral penem antibiotic with broad-spectrum activities against Gram-positive and Gram-negative bacteria. 了解更多
  16. APX-115 free base

    Catalog No. A22055
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    pan NADPH oxidase (Nox) inhibitor
    APX-115 free base (Ewha-18278 free base) is a potent, orally active pan NADPH oxidase (Nox) inhibitor with Ki values of 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2 and Nox4, respectively. 了解更多
  17. Mizagliflozin

    Catalog No. A22056
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    SGLT1 inhibitor
    Mizagliflozin (DSP-3235 free base) is a potent, orally active and selective SGLT1 inhibitor, with a Ki of 27 nM for human SGLT1. 了解更多
  18. TLR4-IN-C34

    Catalog No. A22057
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    TLR4 inhibitor
    TLR4-IN-C34 is an orally active TLR4 inhibitor and reduces systemic inflammation in models of endotoxemia and necrotizing enterocolitis. 了解更多
  19. KGA-2727

    Catalog No. A22062
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    SGLT1 inhibitor
    KGA-2727 is a first selective, high-affinity and orally active SGLT1 inhibitor with Kis of 97.4 nM and 43.5 nM for human and rat SGLT1, respectively. 了解更多
  20. 9-ING-41

    Catalog No. A22066
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    glycogen synthase kinase-3β (GSK-3β) inhibitor
    9-ING-41 is a maleimide-based ATP-competitive and selective glycogen synthase kinase-3β (GSK-3β) inhibitor with an IC50 of 0.71 μM. 了解更多
  21. BAY 2416964

    Catalog No. A22067
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    aryl hydrocarbon receptor (AHR) antagonist
    BAY 2416964 is a potent and orally active aryl hydrocarbon receptor (AHR) antagonist extracted from patent WO2018146010A1, example 192, has an IC50 of 341 nM. BAY 2416964 has the potential for solid tumors treatment. 了解更多
  22. GSK046

    Catalog No. A22068
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    BD2 bromodomain inhibitor of the BET proteins
    GSK046 (iBET-BD2) is a potent, selective and orally active BD2 bromodomain inhibitor of the BET proteins, with IC50s of 264 nM (BRD2 BD2), 98 nM (BRD3 BD2), 49 nM (BRD4 BD2) and 214 nM (BRDT BD2), respectively. 了解更多
  23. CWP232228

    Catalog No. A22070
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    Wnt/β-catenin signaling inhibitor
    CWP232228, a highly potent selective Wnt/β-catenin signaling inhibitor, antagonizes binding of β-catenin to T-cell factor (TCF) in the nucleus. 了解更多
  24. HA155

    Catalog No. A22079
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    Autotaxin Inhibitor IV
    HA155, also known as Autotaxin Inhibitor IV, is a boronic acid-based compound that inhibits autotaxin (IC50 = 5.7 nM) by selectively binding to its catalytic threonine. 了解更多
  25. ML299

    Catalog No. A22094
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    PLD1/PLD2 dual inhibitor
    ML299 (VU0463568) is a dual inhibitor of PLD1 and PLD2 with IC50 of 6 nM and 20 nM, respectively. 了解更多
  26. MCC950

    Catalog No. A22097
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    inhibitor of NLRP3 (NOD-like receptor (NLR) family
    MCC950 (CP-456773, CRID3) is a potent and selective inhibitor of NLRP3 (NOD-like receptor (NLR) family, pyrin domain-containing protein 3) with IC50 of 7.5 nM and 8.1 nM in BMDMs and HMDMs, respectively. 了解更多
  27. BPU-11

    Catalog No. A22101
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    HCN4 CLP ligand
    BPU-11 is a HCN4 CLP ligand. It acts by modulating channel function and completely abolishing the cAMP-induced shift in V1/2. 了解更多
  28. PD-089828

    Catalog No. A22103
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    ATP competitive inhibitor of FGFR-1, PDGFR-β and EGFR
    PD089828 is an ATP competitive inhibitor of FGFR-1, PDGFR-β and EGFR with IC50 of 0.15 ?M, 1.76 ?M, and 5.47 ?M, respectively. 了解更多
  29. ONO-8130

    Catalog No. A22113
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    antagonist of EP1 receptor
    ONO-8130 is an orally available antagonist of EP1 receptor. 了解更多
  30. MSBN

    Catalog No. A22114
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    fluorogenic probe
    MSBN is a highly selective fluorogenic probe for thiols, selectively imaging thiols in live cells and specifically label protein thiols with a turn-on signal to determine diverse reversible protein thiol modifications. 了解更多
  31. Cytosporone B

    Catalog No. A22115
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    nuclear orphan receptor Nur77/NR4A1 agonist
    Cytosporone B (Csn-B; Dothiorelone G) is a naturally occurring nuclear orphan receptor Nur77/NR4A1 agonist with an EC50 of 0.278 nM. 了解更多
  32. FLTX1

    Catalog No. A22120
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    antiestrogenic properties
    FLTX1 is a fluorescent Tamoxifen derivative that can specifically label intracellular Tamoxifen-binding sites (estrogen receptors) under permeabilized and non-permeabilized conditions. FLTX1 exhibits the potent antiestrogenic properties of Tamoxifen in breast cancer cells. FLTX1 is devoid of the estrogenic agonistic effect on the uterus. 了解更多
  33. Epiblastin A

    Catalog No. A22121
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    inhibitor of Casein Kinase 1 (CK1)
    Epiblastin A is an inhibitor of Casein Kinase 1 (CK1) that engages CK1 isoenzymes in cell lysate and induces efficient conversion of epiblast stem cells (EpiSCs) into embryonic stem cells (cESCs). 了解更多
  34. PythiDC

    Catalog No. A22127
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    inhibitor of collagen prolyl 4-hydroxylase
    PythiDC is a selective inhibitor of collagen prolyl 4-hydroxylase. 了解更多
  35. (Z)-JIB-04

    Catalog No. A22137
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    Jumonji histone demethylase inihibitor
    Z-JIB-04 (NSC 693627, JIB-04 Z-isomer) is an isomer of JIB-04. JIB-04 is a pan-selective Jumonji histone demethylase inihibitor with IC50 of 230 nM, 340 nM, 855 nM, 445 nM, 435 nM, 1100 nM and 290 nM for JARID1A, JMJD2E, JMJD3, JMJD2A, JMJD2B, JMJD2C, and JMJD2D, respectively. 了解更多
  36. MSA-2

    Catalog No. A22139
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    non-nucleotide STING agonist
    MSA-2, a potent and orally available non-nucleotide STING agonist, is bound to STING as a noncovalent dimer with nanomolar affinity. 了解更多
  37. ASLAN003

    Catalog No. A22140
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    Dihydroorotate Dehydrogenase (DHODH) inhibitor
    ASLAN003 is an orally active and potent Dihydroorotate Dehydrogenase (DHODH) inhibitor with an IC50 of 35 nM for human DHODH enzyme. 了解更多
  38. (Rac)-JBJ-04-125-02

    Catalog No. A22141
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    EGFR inhibitor
    (Rac)-JBJ-04-125-02 is the racemate of JBJ-04-125-02. JBJ-04-125-02 is a potent, mutant-selective, allosteric and orally active EGFR inhibitor with an IC50 of 0.26 nM for EGFRL858R/T790M. 了解更多
  39. Soporidine

    Catalog No. A22145
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    strigolactone (SL) antagonist
    Soporidine is a strigolactone (SL) antagonist and inhibitor of germination in their biological assays. It binds AtHTL and specifically interferes with SL signaling. 了解更多
  40. ERDRP-0519

    Catalog No. A22150
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    inhibitor of polymerase
    ERDRP-0519 is an orally available inhibitor of polymerase that shows efficacy against a lethal morbillivirus infection in a large animal model. 了解更多
  41. Prexasertib HCl

    Catalog No. A22156
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    ATP-competitive CHK1 inhibitor
    Prexasertib (LY2606368) is an ATP-competitive CHK1 inhibitor with a Ki value of 0.9 nmol/L. For CHK2 and RSK, its IC50 values are 8 nM and 9 nM respectively in cell-free assay. 了解更多
  42. JBSNF-000088

    Catalog No. A22190
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    NNMT inhibitor
    JBSNF-000088 (6-Methoxynicotinamide), a analog of nicotinamide (NA), is a potent Nicotinamide N-methyltransferase (NNMT) inhibitor with IC50s of 1.8 ?M, 2.8 ?M, and 5.0??M for human NNMT, monkey NNMT and mouse NNMT, respectively. 了解更多
  43. (Rac)-Benpyrine

    Catalog No. A22192
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    TNF-α inhibitor
    (Rac)-Benpyrine, a racemate of Benpyrine, is a potent and orally active TNF-α inhibitor. (Rac)-Benpyrine has the potential for TNF-α mediated inflammatory and autoimmune disease research. 了解更多
  44. FOY 251

    Catalog No. A22196
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    proteinase inhibitor
    FOY 251, an anti-proteolytic active metabolite Camostate (HY-13512), acts as a proteinase inhibitor. FOY 251 inhibits SARS-CoV-2 infection in cells assay. 了解更多
  45. AUNP-12

    Catalog No. A22274
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    peptide antagonist
    AUNP-12 (NP-12) is a peptide antagonist of the PD-1 signaling pathway, displays equipotent antagonism toward PD-L1 and PD-L2 in rescue of lymphocyte proliferation and effector functions. 了解更多
  46. Sodium oxamate

    Catalog No. A22275
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    LDH inhibitor
    Sodium oxamate (SO, Aminooxoacetic acid, Oxamic acid) is an inhibitor of lactate dehydrogenase (LDH) that specificly inhibits LDH?A. 了解更多
  47. JX06

    Catalog No. A22283
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    PDK inhibitor
    JX06 is a potent, selective and covalent inhibitor of PDK. JX06 inhibits PDK1, PDK2 and PDK3 with IC50s of 49 nM, 101 nM, and 313 nM, respectively. 了解更多
  48. MLS000532223

    Catalog No. A22285
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    Rho family GTPases inhibitor
    MLS000532223 is a high affinity, selective inhibitor of Rho family GTPases, with EC50 values ranging from 16 μM to 120 μM. 了解更多
  49. Amarogentin

    Catalog No. A22286
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    bitter taste receptor TAS2R1 agonist
    Amarogentin (AG), a secoiridoid glycoside mainly extracted from Swertia and Gentiana roots, exhibits anti-oxidative, anti-tumour, and anti-diabetic activities. Amarogentin is an agonist for the bitter taste receptor TAS2R1 and inhibits in LAD-2 cells substance P-induced production of newly synthesized TNF-α. 了解更多
  50. HA-100 dihydrochloride

    Catalog No. A22289
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    PKs inhibitor
    HA-100 is an isoquinoline compound with an added piperazinylsulfonyl group that acts as an inhibitor of protein kinases (PKs), including PKA, PKC, and PKG (IC50s = 8, 12, and 4 ?M, respectively). 了解更多

产品 1 到 50 共 2943个

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