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产品 1 到 50 共 9795个

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  1. Docosahexaenoic Acid

    Catalog No. A18205
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    Docosahexaenoic Acid (DHA) is an omega-3 fatty acid abundantly present brain and retina. It can be obtained directly from fish oil and maternal milk. 了解更多
  2. Auranofin

    Catalog No. A18996
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    Auranofin is a gold salt classified by the World Health Organization as an antirheumatic agent. It is a gold-thiol complex with anti-inflammatory and immunosuppressive actions. 了解更多
  3. Adenosine deaminase

    Catalog No. A19330
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    Adenosine deaminase is an enzyme that catalyzes the irreversible deamination of adenosine and 2'-deoxyadenosine to inosine and 2'-deoxyinosine, respectively. 了解更多
  4. Thrombin

    Catalog No. A18861
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    digest GST-tagged proteins
    Thrombin is a trypsin-like allosteric serine protease. Thrombin enables site-specific cleavage of fusion proteins with an accessible Thrombin recognition sequence and can be used to digest GST-tagged proteins. 了解更多
  5. Angiotensin III

    Catalog No. A18943
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    angiotensin 1 (AT1) and AT2 receptor agonist
    Angiotensin III is an angiotensin 1 (AT1) and AT2 receptor agonist. 了解更多
  6. Melanin

    Catalog No. A19576
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    unique pigment
    Melanin is a unique pigment with myriad functions. It is multifunctional, providing defense against environmental stresses such as ultraviolet (UV) light, oxidizing agents and ionizing radiation. 了解更多
  7. Xylan

    Catalog No. A19997
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    Xylan represents the main hemicellulose component in the secondary plant cell walls of flowering plants. Xylan is a polysaccharide made from units of xylose and contains predominantly β-D-xylose units linked as in cellulose. 了解更多
  8. Lignine

    Catalog No. A20324
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    Lignine (Lignin) is a complex organic polymer, which plays an important role in plant cell wall structure. 了解更多
  9. Saponins

    Catalog No. A16691
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    Saponins are a class of chemical compounds of glycosides found in particular abundance in various plant species. In plants, saponins may serve as anti-feedants, and to protect the plant against microbes and fungi. 了解更多
  10. Hypotaurine

    Catalog No. A20590
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    Hypotaurine (2-aminoethanesulfinic acid), an intermediate in taurine biosynthesis from cysteine in astrocytes, is an endogenous inhibitory amino acid of the glycine receptor. 了解更多
  11. Calcium polystyrene sulfonate

    Catalog No. A18233
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    used to treat hyperkalemia in patients with chronic kidney disease (CKD)
    Calcium polystyrene sulfonate is an ion-exchange resin used for reducing blood levels of potassium. Calcium polystyrene sulfonate is used to treat hyperkalemia in patients with chronic kidney disease (CKD). 了解更多
  12. Cinnamylamine

    Catalog No. A20835
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    Cinnamylamine can be used for the preparation of Tranylcypromine, a drug that acts as a nonselective and irreversible inhibitor of the enzyme monoamine oxidase (MAO), and is used as an antidepressant and anxiolytic agent. 了解更多
  13. IRL-1620

    Catalog No. A21080
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    endothelin receptor type B (ETB) agonist
    IRL-1620 is a potent and selective endothelin receptor type B (ETB) agonist with a Ki of 16 pM. 了解更多
  14. Peptide 401

    Catalog No. A13913
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    Peptide 401, a potent mast cell degranulating factor from bee venom, suppresses the increased vascular permeability due to intradermal injection of various smooth muscle spasmogens (histamine, and 5-HT). 了解更多
  15. Exendin-4

    Catalog No. A21580
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    glucagon-like peptide-1 receptor agonist
    Exendin-4 (Exenatide), a 39 amino acid peptide, is a long-acting glucagon-like peptide-1 receptor agonist with an IC50 of 3.22 nM. 了解更多
  16. SR-717

    Catalog No. A22048
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    non-nucleotide STING agonist
    SR-717 is a non-nucleotide STING agonist with EC50s of 2.1 μM and 2.2 μM in ISG-THP1 (WT) and ISG-THP1 cGAS KO (cGAS KO) cell lines, respectively. 了解更多
  17. Apilimod mesylate

    Catalog No. A22049
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    IL-12/IL-23 inhibitor
    Apilimod (STA 5326) mesylate is a potent IL-12/IL-23 inhibitor, and strongly inhibits IL-12 with IC50s of 1 nM and 2 nM, in IFN-γ/SAC-stimulated human PBMCs and SAC-treated monkey PBMCs, respectively. 了解更多
  18. Sulopenem

    Catalog No. A22051
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    beta-lactamase inhibitor
    Sulopenem (CP-70429) is an orally active, potent inhibitor of beta-lactamase. Sulopenem is a parenteral penem antibiotic with broad-spectrum activities against Gram-positive and Gram-negative bacteria. 了解更多
  19. LC3-mHTT-IN-AN1

    Catalog No. A22054
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    mHTT-LC3 linker compound
    LC3-mHTT-IN-AN1 (Compound AN1) is a mHTT-LC3 linker compound, which interacts with both mutant huntingtin protein (mHTT) and LC3B but not with wtHTT or irrelevant control proteins. 了解更多
  20. APX-115 free base

    Catalog No. A22055
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    pan NADPH oxidase (Nox) inhibitor
    APX-115 free base (Ewha-18278 free base) is a potent, orally active pan NADPH oxidase (Nox) inhibitor with Ki values of 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2 and Nox4, respectively. 了解更多
  21. Mizagliflozin

    Catalog No. A22056
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    SGLT1 inhibitor
    Mizagliflozin (DSP-3235 free base) is a potent, orally active and selective SGLT1 inhibitor, with a Ki of 27 nM for human SGLT1. 了解更多
  22. TLR4-IN-C34

    Catalog No. A22057
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    TLR4 inhibitor
    TLR4-IN-C34 is an orally active TLR4 inhibitor and reduces systemic inflammation in models of endotoxemia and necrotizing enterocolitis. 了解更多
  23. KGA-2727

    Catalog No. A22062
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    SGLT1 inhibitor
    KGA-2727 is a first selective, high-affinity and orally active SGLT1 inhibitor with Kis of 97.4 nM and 43.5 nM for human and rat SGLT1, respectively. 了解更多
  24. BAY 2416964

    Catalog No. A22067
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    aryl hydrocarbon receptor (AHR) antagonist
    BAY 2416964 is a potent and orally active aryl hydrocarbon receptor (AHR) antagonist extracted from patent WO2018146010A1, example 192, has an IC50 of 341 nM. BAY 2416964 has the potential for solid tumors treatment. 了解更多
  25. GSK046

    Catalog No. A22068
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    BD2 bromodomain inhibitor of the BET proteins
    GSK046 (iBET-BD2) is a potent, selective and orally active BD2 bromodomain inhibitor of the BET proteins, with IC50s of 264 nM (BRD2 BD2), 98 nM (BRD3 BD2), 49 nM (BRD4 BD2) and 214 nM (BRDT BD2), respectively. 了解更多
  26. DiZPK

    Catalog No. A22069
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    photocrosslinker
    DiZPK is a photocrosslinker for identifying direct protein-protein interactions in living prokaryotic and eukaryotic cells. 了解更多
  27. HS-243

    Catalog No. A22071
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    transforming growth factor-?beta kinase inhibitor
    HS-243 is an inhibitor of transforming growth factor-?beta kinase. HS-243 can be used in treatment of cancer, malaria, inflammatory and other TAK1-?mediated diseases. 了解更多
  28. CYM50308

    Catalog No. A22072
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    sphingosine-1-phosphate receptor 4 (S1P4-R) agonist
    CYM50308 (ML248) is a potent, selective and high affinity sphingosine-1-phosphate receptor 4 (S1P4-R) agonist with an EC50 of 56 nM. 了解更多
  29. CRANAD-2

    Catalog No. A22076
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    near-infrared (NIR) probe
    CRANAD-2 is a curcumin-derivatized near-infrared (NIR) probe that meets all the requirements for a NIR contrast agent for the detection of Abeta plaques both in vitro and in vivo. 了解更多
  30. DGY-06-116

    Catalog No. A22077
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    Src inhibitor
    DGY-06-116 is an irreversible covalent, selective Src inhibitor. 了解更多
  31. HA155

    Catalog No. A22079
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    Autotaxin Inhibitor IV
    HA155, also known as Autotaxin Inhibitor IV, is a boronic acid-based compound that inhibits autotaxin (IC50 = 5.7 nM) by selectively binding to its catalytic threonine. 了解更多
  32. BMS453

    Catalog No. A22082
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    RARβ agonist
    BMS453 (BMS-189453), a synthetic retinoid, is a RARβ agonist and a RARα/RARγ antagonist. 了解更多
  33. 4BP-TQS

    Catalog No. A22084
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    neuronal nicotinic acetylcholine receptors agonist
    4BP-TQS is an allosteric agonist of α7 subunit-containing neuronal nicotinic acetylcholine receptors (nAChRs). 了解更多
  34. ML191

    Catalog No. A22088
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    GPR55 antagonist
    ML191 (CCG-152883, CID-23612552) is an antagonist of GPR55 with EC50 of 1.076 ?M in U2OS cells overexpressing GPR55. 了解更多
  35. YM26734

    Catalog No. A22091
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    rabbit platelet sPLA2 inhibitor
    YM-26734 is a rabbit platelet sPLA2 inhibitor that has been used to ameliorate local inflammatory responses in TPA-induced mouse ear edema. 了解更多
  36. CYM 2503

    Catalog No. A22092
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    positive allosteric modulator (PAM)
    CYM2503 is a positive allosteric modulator (PAM) of the GAL2 receptor that potentiates galanin-induced IP1 production in vitro. 了解更多
  37. API-1

    Catalog No. A22093
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    Akt inhibitor
    API-1 (NSC 177223) is a potent inhibitor of Akt that induces GSK3-dependent, β-TrCP- and FBXW7-mediated Mcl-1 degradation, resulting in induction of apoptosis. 了解更多
  38. ML299

    Catalog No. A22094
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    PLD1/PLD2 dual inhibitor
    ML299 (VU0463568) is a dual inhibitor of PLD1 and PLD2 with IC50 of 6 nM and 20 nM, respectively. 了解更多
  39. SW155246

    Catalog No. A22095
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    DNMT1 inhibitor
    SW155246 is a potent and selective DNMT1 (DNA methyltransferase 1) inhibitor with IC50 of 1.2 μM. SW155246 induces re-expression of the tumor suppressor geneRASSF1 in A549 cells. 了解更多
  40. MCC950

    Catalog No. A22097
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    inhibitor of NLRP3 (NOD-like receptor (NLR) family
    MCC950 (CP-456773, CRID3) is a potent and selective inhibitor of NLRP3 (NOD-like receptor (NLR) family, pyrin domain-containing protein 3) with IC50 of 7.5 nM and 8.1 nM in BMDMs and HMDMs, respectively. 了解更多
  41. SR8278

    Catalog No. A22100
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    nuclear heme receptor REV-ERB synthetic antagonist
    SR8278 is a competitive nuclear heme receptor REV-ERB synthetic antagonist. 了解更多
  42. BPU-11

    Catalog No. A22101
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    HCN4 CLP ligand
    BPU-11 is a HCN4 CLP ligand. It acts by modulating channel function and completely abolishing the cAMP-induced shift in V1/2. 了解更多
  43. CRANAD-28

    Catalog No. A22102
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    two-photon imaging probe
    CRANAD-28, a blood brain barrier (BBB) penetrable two-photon imaging probe, acts by labelling plaques and cerebral amyloid angiopathies (CAAs). 了解更多
  44. PD-089828

    Catalog No. A22103
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    ATP competitive inhibitor of FGFR-1, PDGFR-β and EGFR
    PD089828 is an ATP competitive inhibitor of FGFR-1, PDGFR-β and EGFR with IC50 of 0.15 ?M, 1.76 ?M, and 5.47 ?M, respectively. 了解更多
  45. WAY-169916

    Catalog No. A22105
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    pathway-selective inhibitor of estrogen receptor (ER)
    WAY-169916 is a pathway-selective inhibitor of estrogen receptor (ER) that acts by inhibiting NF-kB transcriptional activity. 了解更多
  46. SGA360

    Catalog No. A22106
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    modulator of aryl hydrocarbon (Ah) receptor
    SGA360 is a selective modulator of aryl hydrocarbon (Ah) receptor that exhibits anti-inflammatory properties. 了解更多
  47. AEM1

    Catalog No. A22108
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    inhibitor of deregulated NRF2 transcriptional activity
    AEM1 is an inhibitor of deregulated NRF2 transcriptional activity in cancer. 了解更多
  48. RH01687

    Catalog No. A22110
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    β-cell protector
    RH01687 is a potent β-cell protector that exhibits β-cell-protective activities against endoplasmic reticulum (ER) stress. 了解更多
  49. Creatine riboside

    Catalog No. A22112
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    urinary metabolite
    Creatine riboside is a urinary metabolite and is a diagnostic and prognostic biomarker of lung cancer. 了解更多
  50. ONO-8130

    Catalog No. A22113
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    antagonist of EP1 receptor
    ONO-8130 is an orally available antagonist of EP1 receptor. 了解更多

产品 1 到 50 共 9795个

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