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“jwh 249”的搜索结果

产品 1 到 50 共 121个

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  1. Cyclopamine
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    Cyclopamine

    Catalog No. A10249
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    Hedgehog signaling 抑制剂
    Cyclopamine是一种特异性的Hedgehog (Hh)信号通路拮抗剂，作用于Smoothened (Smo)，IC50为46 nM。Cyclopamine 抑制Hedgehog信号通路， IC50 为46 nM。 了解更多
  2. NVP-BSK805
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    NVP-BSK805

    Catalog No. A11193
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    JAK 抑制剂
    NVP-BSK805是喹喔啉JAK2抑制剂对红细胞增多症的有效和选择性抑制，喹喔啉JAK2抑制剂可有效抑制小鼠和大鼠中重组人促红细胞生成素诱导的红细胞增多症和髓外红细胞生成。IC50为0.5 nM，比作用于JAK1， JAK3和TYK2选择性高20倍以上。 了解更多
  3. SNS-314
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    SNS-314

    Catalog No. A10851
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    Aurora 抑制剂
    SNS-314 Mesylate是Aurora A，Aurora B和Aurora C的有效和选择性抑制剂，IC50分别为9 nM，31 nM和3 nM。 它对Trk A/B，Flt4，Fms，Axl，c-Raf和DDR2的效力较低。 阶段1。 了解更多
  4. Gastrodin (Gastrodine)
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    Gastrodin (Gastrodine)

    Catalog No. A10418
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    Gastrodin (Gastrodine)是一种多酚。它是4-羟基苯甲醇(天麻素)的糖苷。 了解更多
  5. Tolterodine tartrate (Detrol LA)
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    Tolterodine tartrate (Detrol LA)

    Catalog No. A10937
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    muscarinic receptor 拮抗剂
    Tolterodine tartrate (Detrol LA)是毒蕈碱受体拮抗剂。 了解更多
  6. Varenicline
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    Varenicline

    Catalog No. A10966
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    nAChR partial agonist
    Varenicline是烟碱样受体部分激动剂。 了解更多
  7. Anamorelin
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    Anamorelin

    Catalog No. A12346
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    Anamorelin是一种新型 ghrelin receptor激动剂，FLIPR 检测中，EC50 为 0.74 nM，用于治疗与恶病质/厌食症相关的非小肺癌。 了解更多
  8. Pirarubicin
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    Pirarubicin

    Catalog No. A10735
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    Topoisomerase II 抑制剂
    Pirarubicin是蒽环类抗肿瘤阿霉素的类似物。插入DNA中并与Topo II（拓扑异构酶II）相互作用并抑制DNA复制。 了解更多
  9. SB 334867
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    SB 334867

    Catalog No. A12786
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    OX1 receptor 拮抗剂
    SB 334867是一种选择性的非肽orexin OX1受体拮抗剂。对于分别表达人OX1和OX2受体的CHO细胞中的细胞内Ca2 +释放抑制，pKb值为7.2和<5。体内全身给药后，阻断orexin-A诱导的美容和进食。 了解更多
  10. AZD5423
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    AZD5423

    Catalog No. A13249
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    nonsteroidal glucocorticoid receptor 激动剂
    AZD5423是新型的非甾体类糖皮质激素受体激动剂。 了解更多
  11. RU 24969 hemisuccinate
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    RU 24969 hemisuccinate

    Catalog No. A13833
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    5-HT1A/1B and 5-HT2C 激动剂
    RU 24969 hemisuccinate是有效的5-HT1A/1B和中度5-HT2C激动剂，也可能释放5-HT。 了解更多
  12. SB225002
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    SB225002

    Catalog No. A14209
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    CXCR2 拮抗剂
    SB225002是一种有效的选择性CXCR2拮抗剂，IC50为22 nM，可抑制白介素IL-8与CXCR2的结合，选择性是其他测试的7-TMR的150倍以上。 了解更多
  13. SH-4-54
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    SH-4-54

    Catalog No. A14249
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    Stat 抑制剂
    SH-4-54是一种有效的STAT抑制剂，对STAT3和STAT5的KD为300 nM和464 nM。 了解更多
  14. Hederagenin
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    Hederagenin

    Catalog No. A13952
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    Hederagenin三萜皂角苷用于研究三萜皂角苷作为生物农药的特性，可防止真菌生长，细菌生长和病毒性植物病。 了解更多
  15. PFK-158
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    PFK-158

    Catalog No. A14398
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    PFK-2/FBPase 抑制剂
    PFK-158是6-磷酸果糖-2-激酶/果糖-2,6-双磷酸酶（PFK-2/FBPase）同工型3（PFKFB3）的抑制剂，是3-(3-吡啶基)-1-[4-吡啶基]-2-丙烯-1-酮(3PO)，具有潜在的抗肿瘤活性。 了解更多
  16. CEP-32496
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    CEP-32496

    Catalog No. A13772
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    Raf 抑制剂
    CEP-32496是一种口服v-raf鼠肉瘤病毒癌基因同源物B1（B-raf）丝氨酸/苏氨酸蛋白激酶抑制剂，具有潜在的抗肿瘤活性。 了解更多
  17. TNP-470
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    TNP-470

    Catalog No. A14014
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    MetAP-2 抑制剂
    TNP 470是富马西林的类似物，在体外显示有效的抗血管生成活性。已显示出抑制MetAP-2（甲硫氨酸氨基肽酶II型）的作用。 了解更多
  18. Bisdemethoxycurcumin
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    Bisdemethoxycurcumin

    Catalog No. A14544
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    Bisdemethoxycurcumin是姜黄素的天然去甲氧基衍生物。 了解更多
  19. Demethoxycurcumin
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    Demethoxycurcumin

    Catalog No. A14545
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    Demethoxycurcumin是姜黄素的天然脱甲氧基衍生物。 了解更多
  20. Raddeanoside R8
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    Raddeanoside R8

    Catalog No. A14609
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    Raddeanoside R8提取自海葵Raddeana。 了解更多
  21. Epidermal Growth Factor Receptor Peptide (985-996)
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    Epidermal Growth Factor Receptor Peptide (985-996)

    Catalog No. A14877
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    Epidermal Growth Factor Receptor Peptide (985-996)存在于细胞表面，并通过其特定配体（包括表皮生长因子和转化生长因子）的结合而被激活。 了解更多
  22. CEP-32496 hydrochloride
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    CEP-32496 hydrochloride

    Catalog No. A15040
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    Raf 抑制剂
    CEP-32496 hydrochloride是野生型BRAF，V600E突变型BRAF和c-Raf的高效抑制剂，Kd值分别为14 nM，36 nM和39 nM。 了解更多
  23. ST-836 hydrochloride
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    ST-836 hydrochloride

    Catalog No. A15249
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    ST-836 hydrochloride是多巴胺受体配体；反帕金森氏剂。 了解更多
  24. NFAT Inhibitor
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    NFAT Inhibitor

    Catalog No. A15381
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    NFAT 抑制剂
    NFAT Inhibitor是钙调神经磷酸酶介导的活化T细胞核因子（NFAT）的去磷酸化的选择性抑制剂。 了解更多
  25. NG52
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    NG52

    Catalog No. A12494
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    Cell cycle-regulating kinase 抑制剂
    NG52 (Compound 52)是细胞周期调节激酶Cdc28p（IC50 = 7 μM）和相关Pho85p激酶（IC50 = 2 μM）的有效，可渗透细胞，可逆，选择性和ATP兼容的抑制剂。 了解更多
  26. Thiotepa
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    Thiotepa

    Catalog No. A10930
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    Thiotepa是一种多官能的有机磷烷基化剂，是N，N'，N''-三亚乙基磷酰胺（TEPA）的稳定衍生物，具有抗肿瘤活性。 了解更多
  27. AMG 548
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    AMG 548

    Catalog No. A10970
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    p38 MAPK 抑制剂
    AMG 548是有效的p38α选择性抑制剂。它对其他36种激酶表现出> 1000倍的选择性，并且抑制全血LPS刺激的TNFα。 了解更多
  28. Aleglitazar
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    Aleglitazar

    Catalog No. A12492
    PPAR-α/γ 激动剂
    Aleglitazar是一种新型的双重PPAR-α/γ激动剂，IC50为2.8 nM/4.6 nM。 了解更多
  29. ALW-II-41-27
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    ALW-II-41-27

    Catalog No. A12493
    Eph receptor 抑制剂
    ALW-II-41-27是新型的Eph受体酪氨酸激酶抑制剂。 了解更多
  30. Diflunisal
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    Diflunisal

    Catalog No. A16166
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    COX 抑制剂
    Diflunisal是具有止痛和抗炎活性的水杨酸衍生物。 了解更多
  31. FLT3-IN-1
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    FLT3-IN-1

    Catalog No. A16249
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    FLT3 抑制剂
    FLT3-IN-1是一种新型的有效选择性Flt3抑制剂，IC50为10 nM。抗表达FLT3-ITD的MV4-11细胞，IC50为6 nM。 了解更多
  32. Aceglutamide
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    Aceglutamide

    Catalog No. A16388
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    Aceglutamide是一种精神刺激药，促智药，可作为谷氨酰胺的前药，具有增强的效力和稳定性。 了解更多
  33. Azacosterol
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    Azacosterol

    Catalog No. A13295
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    24-DHCR 抑制剂
    Azacosterol可作为24-脱氢胆固醇还原酶（24-DHCR）的抑制剂，可防止去甾醇形成胆固醇。 了解更多
  34. CBX3 Human
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    CBX3 Human

    Catalog No. AP0249
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    Chromobox Homolog 3 Human Recombinant 了解更多
  35. RPS16 Human
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    RPS16 Human

    Catalog No. AP0771
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    Ribosomal Protein S16 Human Recombinant 了解更多
  36. SNIP1 Human
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    SNIP1 Human

    Catalog No. AP1249
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    Smad Nuclear Interacting Protein 1 Human Recombinant 了解更多
  37. RAB11A Human
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    RAB11A Human

    Catalog No. AP2236
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    RAB11A, Member RAS Oncogene Family Human Recombinant 了解更多
  38. NCK1 Human
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    NCK1 Human

    Catalog No. AP2249
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    NCK Adaptor Protein 1 Human Recombinant 了解更多
  39. Artemin Human
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    Artemin Human

    Catalog No. AP2490
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    Artemin Human Recombinant 了解更多
  40. NGB Human
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    NGB Human

    Catalog No. AP2491
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    Neuroglobin Human Recombinant 了解更多
  41. NT 4 Human
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    NT 4 Human

    Catalog No. AP2492
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    Neurotrophin-4 Human Recombinant 了解更多
  42. NT 3 Mouse
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    NT 3 Mouse

    Catalog No. AP2493
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    Neurotrophin-3 Mouse Recombinant 了解更多
  43. MTPN Human
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    MTPN Human

    Catalog No. AP2494
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    Myotrophin Human Recombinant 了解更多
  44. NENF Human
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    NENF Human

    Catalog No. AP2495
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    Neudesin Neurotrophic Factor Human Recombinant 了解更多
  45. NEUROG3 Human
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    NEUROG3 Human

    Catalog No. AP2496
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    Neurogenin 3 Human Recombinant 了解更多
  46. NRTN Human
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    NRTN Human

    Catalog No. AP2497
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    Neurturin Human Recombinant 了解更多
  47. NNT1 Human
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    NNT1 Human

    Catalog No. AP2498
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    Neurotrophin-1 Human Recombinant 了解更多
  48. NGFR Human
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    NGFR Human

    Catalog No. AP2499
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    Nerve Growth Factor Receptor Human Recombinant 了解更多
  49. GHRP 2 Human
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    GHRP 2 Human

    Catalog No. AP3249
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    Growth Hormone Releasing Peptide-2 Human 了解更多
  50. CDK2 Human
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    CDK2 Human

    Catalog No. AP3833
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    Cyclin-Dependent Kinase 2 Human Recombinant 了解更多

产品 1 到 50 共 121个

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