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Imidacloprid-urea
Catalog No. A22253 marine xenobiotic metaboliteImidacloprid-urea with a role as a marine xenobiotic metabolite, is the primary imidacloprid soil metabolite, whereas imidacloprid-olefin is the main plant-relevant metabolite and is more toxic to insects than imidacloprid. 了解更多 -
Finasteride Carboxaldehyde
Catalog No. A22255 used for proteomics researchFinasteride Carboxaldehyde is a metabolite of Finasteride in human bile (M2 metabolite) that can be used for proteomics research. 了解更多 -
Ferulic acid methyl ester
Catalog No. A22364 antioxidant agentFerulic acid methyl ester (Methyl Ferulate, Methyl 4'-hydroxy-3'-methoxycinnamate) is a lipophilic derivative of ferulic acid, which is a hydroxycinnamic acid that is abundant in plants. It shows the strongest antioxidant activity and can protect against inflammation and cancer. 了解更多 -
Tirabrutinib hydrochloride
Catalog No. A22375 BTK inhibitorTirabrutinib (ONO-4059) hydrochloride is a selective and novel inhibitor of BTK with IC50 2.2 nm, Tirabrutinib binds to BTK within B cells, thereby preventing B-cell receptor signaling and impeding B-cell development. 了解更多 -
Cyasterone
Catalog No. A22387 EGFR inhibitorCyasterone, a natural EGFR inhibitor, mainly isolated from Ajuga decumbens Thunb (Labiatae). 了解更多 -
Rotundic acid
Catalog No. A22390 anti-inflammatory agentRotundic acid, a triterpenoid obtained from I. rotunda, induces DNA damage and cell apoptosis in hepatocellular carcinoma through AKT/mTOR and MAPK Pathways. Rotundic acid possesses anti-inflammatory and cardio-protective abilities. 了解更多 -
4-Methyl-2-oxopentanoic acid
Catalog No. A22410 neurotoxin4-Methyl-2-oxopentanoic acid, an abnormal metabolite, is both a neurotoxin and a metabotoxin. 了解更多 -
Methyl 2-(3-oxo-2-(pent-2-en-1-yl)cyclopentyl)acetate
Catalog No. A22411 endogenous metaboliteMethyl 2-(3-oxo-2-(pent-2-en-1-yl)cyclopentyl)acetate is an endogenous metabolite. 了解更多 -
Heptadecanoic acid
Catalog No. A22412 OCS-FAHeptadecanoic acid is an odd chain saturated fatty acid (OCS-FA). Heptadecanoic acid is associated with several diseases, including the incidence of coronary heart disease, prediabetes and type 2 diabetes as well as multiple sclerosis. 了解更多 -
Emamectin Benzoate
Catalog No. A22417 nervoussystem toxicantEmamectin Benzoate (MK-244) is an orally active nervoussystem toxicant by binding g-aminobutyric (GABA) receptor in insects. 了解更多 -
Monomethyl fumarate
Catalog No. A22430 GPR109A agonistMonomethyl fumarate, an active metabolite of Dimethyl fumarate (DMF), is a potent GPR109A agonist. Monomethyl fumarate has the potential for multiple neuroprotective pathways and other models of retinal disease. 了解更多 -
Glycochenodeoxycholic acid
Catalog No. A22444 detergentGlycochenodeoxycholic acid (Chenodeoxycholylglycine) is a bile acid formed in the liver from chenodeoxycholate and glycine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. Glycochenodeoxycholic acid (Chenodeoxycholylglycine) induces hepatocyte apoptosis. 了解更多 -
Glycochenodeoxycholic acid sodium salt
Catalog No. A22447 detergentGlycochenodeoxycholic acid sodium salt (Chenodeoxycholylglycine sodium salt) is a bile acid formed in the liver from chenodeoxycholate and glycine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. Glycochenodeoxycholic acid sodium salt (Chenodeoxycholylglycine sodium salt) induces hepatocyte apoptosis. 了解更多 -
Quisinostat dihydrochloride
Catalog No. A22453 pan-HDAC inhibitorQuisinostat dihydrochloride (JNJ-26481585 dihydrochloride) is an orally available, potent pan-HDAC inhibitor with IC50s of 0.11 nM, 0.33 nM, 0.64 nM, 0.46 nM, and 0.37 nM for HDAC1, HDAC2, HDAC4, HDAC10 and HDAC11, respectively. Quisinostat dihydrochloride has a broad spectrum antitumoral activity. 了解更多 -
Ganoderic acid A
Catalog No. A22461 AK-STAT3 signaling pathway inhibitorGanoderic acid A can inhibit of the JAK-STAT3 signaling pathway, also inhibit proliferation, viability, ROS. 了解更多 -
Pyridostatin TFA salt
Catalog No. A22462 Pyridostatin stabilizes G-quadruplexes (G4s) in cells and elicits a DNA damage response by causing the formation of DNA double strand breaks (DSB). 了解更多 -
Pibrentasvir
Catalog No. A22474 Pibrentasvir, also known as ABT-530, is a protease inhibitor potentially for the treatment of HCV infection. 了解更多 -
PF-06679142
Catalog No. A22484 AMPK activatorPF-06679142 is a potent AMPK activator. PF-06679142 exhibited robust activation of AMPK in rat kidneys as well as desirable oral absorption, low plasma clearance, and negligible renal clearance in preclinical species. 了解更多 -
Emavusertib
Catalog No. A22489 Emavusertib, also known as CA-4948 is a potent IRAK4/FLT3 inhibitor with anti-tumor activity. CA-4948 demonstrated good cellular activity in ABC DLBCL and AML cell lines. CA-4948 demonstrated moderate to high selectivity in a panel of 329 kinases as well as exhibited desirable ADME and PK profiles including good oral bioavailability in mice, rat, and dog and showed >90% tumor growth inhibition in relevant tumor models with excellent correlation with in vivo PD modulation. 了解更多 -
PF-06882961
Catalog No. A22492 GLP-1R agonistPF-06882961 is a potent, orally bioavailable agonist of the glucagon-like peptide-1 receptor agonist (GLP-1R) 了解更多 -
Vodobatinib
Catalog No. A22504 Vodobatinib, also known as K-0706, is a novel 3rd generation (3G) TKI effective against wild-type and mutated BCR-ABL1 with limited off-target activity. 了解更多 -
MC-Gly-Gly-Phe
Catalog No. A22546 MC-Gly-Gly-Phe is a cleavable linker used for antibody-drug conjugates (ADC). 了解更多 -
Boc-Gly-Gly-Phe-Gly-OH
Catalog No. A22547 Boc-Gly-Gly-Phe-Gly-OH is a protease cleavable linker used for the antibody-drug conjugate (ADC). 了解更多 -
Boc-Dap-NE
Catalog No. A22548 Boc-Dap-NE is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). 了解更多 -
JNJ-10198409
Catalog No. A22554 PDGFRα/PDGFRβ inhbitorJNJ 10198409 is a potent platelet-derived growth factor receptor (PDGFR) inhibitor (IC50 values are 4.2 and 45 nM for PDGFRβ and PDGFRα, respectively). Also inhibits c-Abl, Lck, c-Src and Fyn kinases (IC50 values are 22, 100, 185 and 378 nM respectively). 了解更多 -
L-Leucine-13C6
Catalog No. A22557 L-LEUCINE-13C6, also known as 13C6-D-Leucine or L-?Leucine-?1,?2,?3,?4,?5,?5'-?13C6, is a fully 13C labelled D-Leucine. 了解更多 -
SNIPER(CRABP)-11
Catalog No. A22574 PROTAC degraderSNIPER(CRABP)-11, also known as PROTAC cIAP1 degrader-?4, is a potent protein degrader. 了解更多 -
Xanthurenic acid
Catalog No. A22575 II metabotropic glutamate receptor agonistXanthurenic acid is a putative endogenous Group II metabotropic glutamate receptor agonist, on sensory transmission in the thalamus. 了解更多 -
Suberoyl bis-hydroxamic acid
Catalog No. A22581 HDAC1 and HDAC3 inhibitorSuberoyl bis-hydroxamic acid (Suberohydroxamic acid; SBHA) is a competitive and cell-permeable HDAC1 and HDAC3 inhibitor with ID50 values of 0.25 μM and 0.30 μM, respectively. 了解更多 -
Ethyl pyruvate
Catalog No. A22582 anti-inflammatory agentEthyl pyruvate is a simple derivative of the endogenous metabolite, pyruvic acid. Ethyl pyruvate is an anti-inflammatory agent. 了解更多 -
DAPI dihydrochloride
Catalog No. A22602 fluorescent probeDAPI Dihydrochloride is a cell-permeable fluorescent probe used to stain DNA and chromosomes, with a preference for adenine and thymine rich DNA. 了解更多 -
Atabecestat
Catalog No. A22605 BACE1 inhibitorAtabecestat (JNJ-54861911) is a potent brain-penetrant and orally active β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor, achieves robust and high CSF Aβ reduction. 了解更多 -
Lidocaine N-ethyl bromide
Catalog No. A22615 blocker of fast Na+-dependent action potentials and voltage-dependentLidocaine N-ethyl bromide is a non-membrane-permeable blocker of fast Na+-dependent action potentials and voltage-dependent, non-inactivating Na+ conductance. 了解更多 -
Sipoglitazar
Catalog No. A22625 PPARγ agonistSipoglitazar, also known as TAK-654, is a PPARγ agonist potentially for the treatment of diabetes. 了解更多 -
Gabazine free base
Catalog No. A22634 GABA receptor antagonistGabazine free base is a specific GABA receptor antagonist. Does not affect GABA-transaminase or glutamate-decarboxylase activitites. 了解更多 -
Tracazolate
Catalog No. A22635 pyrazolopyridine anxiolyticTracazolate is a pyrazolopyridine anxiolytic known to interact with gamma-aminobutyric acid (GABA)(A) receptors, adenosine receptors, and phosphodiesterases. 了解更多
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