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Oct3/4-inducer-1
Catalog No. A22642 Oct3/4 inducerOct3/4-inducer-1 (compound 2) is a potent Oct3/4 inducer. Oct3/4-inducer-1 promotes expression and stabilization of Oct3/4, and enhances its transcriptional activity in diverse human somatic cells. 了解更多 -
Tizoxanide
Catalog No. A22643 anti-infective agentTizoxanide is the active metabolite of Nitazoxanide, which is a thiazolide anti-infective compound against anaerobic bacteria, protozoa, and a range of viruses. Tizoxanide has anti-HIV-1 activities. 了解更多 -
Multi-kinase inhibitor 1
Catalog No. A22645 multi-kinase inhibitorMulti-kinase inhibitor 1 is a potent multi-kinase inhibitor. Multi-kinase inhibitor 1 has the potential for diseases or disorders associated with abnormal or deregulated tyrosine kinase activity, particularly diseases associated with the activity of PDGF-R, c-Kit and Bcr-abl. 了解更多 -
GABAA Modulator I
Catalog No. A22646 modulator of the GABAA receptor complexGABAA Modulator I is novel modulator of the GABAA receptor complex, and in particular for combating anxiety and related diseases. 了解更多 -
Methoxy-PMS
Catalog No. A22647 active oxygen formation inducerMethoxy-PMS (1-Methoxy PMS), an active oxygen formation inducer, is stable electron-transport mediator between NAD(P)H and tetrazolium dyes. 了解更多 -
Des(benzylpyridyl) Atazanavir
Catalog No. A22649 human immunodeficiency virus protease inhibitorDes(benzylpyridyl) Atazanavir is a metabolite of Atazanavir, a human immunodeficiency virus protease inhibitor. 了解更多 -
THPP-1
Catalog No. A22650 PDE10A inhibitorTHPP-1, a SGC chemical probe, is a potent and orally bioavailable phosphodiesterase 10A (PDE10A) inhibitor, with Ki values of 1 nM and 1.3 nM for human and rat PDE10A, respectively. THPP-1 has excellent pharmacokinetic properties in preclinical species. 了解更多 -
Tetrabenazine Racemate
Catalog No. A22654 VMAT-2 inhibitorTetrabenazine Racemate (Ro 1-9569 Racemate) is a selective and reversible inhibitor of vesicular monoamine transporter-2 (VMAT-2). 了解更多 -
rac-BHFF
Catalog No. A22659 -
Acecainide HCl
Catalog No. A22660 Class III antiarrhythmic agentAcecainide, also known as N-acetylprocainamide and ASL 601, is the N-acetylated metabolite of procainamide. Acecainide is a Class III antiarrhythmic agent. It can be given either intravenously or orally, and is eliminated primarily by renal excretion. 了解更多 -
4-Oxo-4-HPR
Catalog No. A22669 inhibitor of tubulin polymerization4-Oxo-4-HPR is an inhibitor of tubulin polymerization, inducing marked G2-M cell cycle arrest and apoptosis in fenretinide-sensitive and fenretinide-resistant cell lines. It is also a fenretinide metabolite. 了解更多 -
Lvguidingan
Catalog No. A22675 anticonvulsant/antiepileptic agentLvguidingan (Anticonvulsant 7903, 3,4-dichlorophenyl propenylisobutylamide) is an anticonvulsant/antiepileptic agent. Lvguidingan (Anticonvulsant 7903) is found to be able to increase the concentration of 5-HT and 5-HIAA in mice brain. 了解更多 -
Nor-benzetimide
Catalog No. A22684 mAChR antagonistNor-benzetimide is a major metabolite of Benzetimide. Benzetimide is a mAChR antagonist with anticholinergic activity. 了解更多 -
Methotrexate disodium
Catalog No. A17943 antifolate agentMethotrexate (Amethopterin) disodium, an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis. Methotrexate disodium, also an immunosuppressant and antineoplastic agent, is used for the research of rheumatoid arthritis and a number of different cancers (such as acute lymphoblastic leukemia). 了解更多 -
DL-Glutamine
Catalog No. A17925 non-essential amino acidDL-Glutamine (Glutamin, 2-amino-4-carbamoylbutanoic acid) is a non-essential amino acid present abundantly throughout the body and is involved in many metabolic processes. 了解更多 -
Deferoxamine mesylate
Catalog No. A17761 iron chelatorDeferoxamine mesylate is an iron chelator that binds free iron in a stable complex, preventing it from engaging in chemical reactions. 了解更多 -
Phenazine methylsulfate
Catalog No. A17495 free radical generatorPhenazine methylsulfate is a free radical generator. Phenazine methylsulfate has been used as an electron transfer reactant in cell viability assays. 了解更多 -
Ginsenoside Rc
Catalog No. A15565 anti-cancer agentGinsenoside Rc, isolated from Panax ginseng, may exert various activities including anti-cancer, anti-inflammatory, antiobesity, and anti-diabetic effects. 了解更多 -
Sodium butyrate
Catalog No. A10852 histone deacetylase inhibitorSodium butyrate (NaB, Butanoic acid sodium salt), sodium salt of butyric acid, is a histone deacetylase inhibitor and competitively binds to the zinc sites of class I and II histone deacetylases (HDACs). 了解更多 -
Thiamine hydrochloride
Catalog No. A15710 micronutrientThiamine hydrochloride (Thiamine chloride hydrochloride) is an essential micronutrient needed as a cofactor for many central metabolic enzymes. 了解更多 -
(20S)-Protopanaxatriol
Catalog No. A15649 LXRα inhibitor(20S)-Protopanaxatriol is a metabolite of ginsenoside, works through the glucocorticoid receptor (GR) and oestrogen receptor (ER), and is also a LXRα inhibitor. (20S)-Protopanaxatriol shows a broad spectrum of antitumor effects. 了解更多 -
Nortriptyline hydrochloride
Catalog No. A17290 tricyclic antidepressantNortriptyline hydrochloride (Desmethylamitriptyline hydrochloride) is a tricyclic antidepressant and the main active metabolite of Amitriptyline, and used to relieve the symptoms of depression. 了解更多 -
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最新产品
AMG-510 (Sotorasib)
Catalog No. A19021 KRAS G12C covalent inhibitorAMG-510 is a potent, orally bioavailable, and selective KRAS G12C covalent inhibitor with anti-tumor activity. 了解更多 -
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9-Phenanthrol
Catalog No. A17570 TRPM4 blockerSelective TRPM4 blocker (IC50 = 20 μM in HEK293 cells). Exhibits no effect on CFTR or TRPM5 (at 0.25 and 1 mM respectively). Abolishes arrhythmias induced by hypoxia in a mouse heart model. 了解更多 -
PNU-159682
Catalog No. A22023 ADCs cytotoxinPNU-159682, a highly potent metabolite of the anthracycline nemorubicin (DNA topoisomerase II inhibitor) with outstanding cytotoxicity, is a potent ADCs cytotoxin. 了解更多 -
CP-547632 hydrochloride
Catalog No. A22019 VEGFR-2/FGFR inhibitorCP-547632 hydrochloride is a well-tolerated, orally-bioavailable inhibitor of the VEGFR-2 and basic fibroblast growth factor (FGF) kinases with IC50s of 11 nM and 9 nM, respectively. 了解更多 -
Hydroxystilbamidine bis(methanesulfonate)
Catalog No. A22017 cellular ribonucleases inhibitorHydroxystilbamidine bis(methanesulfonate), a dye capable of binding to both DNA and RNA, has been found to be a powerful inhibitor of cellular ribonucleases. 了解更多 -
Pridopidine
Catalog No. A22009 D2R antagonistPridopidine, a dopamine (DA) stabilizer, acts as a low affinity dopamine D2 receptor (D2R) antagonist. 了解更多 -
Eplivanserin
Catalog No. A21967 5-HT2 receptor antagonistEplivanserin is a potent, selective and orally available 5-HT2 receptor antagonist, with an IC50 of 5.8 nM in rat cortical membrane, and a Kd of 1.14 nM. 了解更多 -
4-Phenoxybenzylamine
Catalog No. A20959 4-Phenoxybenzylamine inhibits the function of the NS3 protein by stabilizing an inactive conformation with an IC50 of about 500 μM against FL NS3/4a. 了解更多 -
Calcitriol Impurities D
Catalog No. A20825 impurity of CalcitriolCalcitriol Impurities D is the impurity of Calcitriol, Calcitriol is the hormonally active form of vitamin D, Calcitriol is the active metabolite of vitamin D3 that activates the vitamin D receptor (VDR). 了解更多 -
MK-0941
Catalog No. A20823 allosteric glucokinase activatorMK-0941 is a potent, orally active and allosteric glucokinase activator, with EC50s of 240 and 65 nM for recombinant human glucokinase in the presence of 2.5 and 10 mM glucose, respectively. MK-0941 has potential in the treatment of type 2 diabetes. 了解更多 -
Sodium ionophore III
Catalog No. A20813 Sodium ionophore III (ETH2120) is a Na+ ionophore suitable for the assay of sodium activity in blood, plasma, serum. etc. 了解更多 -
Val-Cit-PAB-MMAE
Catalog No. A20808 drug-linker conjugate for ADCVal-Cit-PAB-MMAE is a drug-linker conjugate for ADC by using the anti-mitotic agent, monomethyl auristatin E (MMAE, a tubulin inhibitor), linked via the peptide Val-Cit-PAB. 了解更多 -
PF-06840003
Catalog No. A20807 IDO-1 inhibitorPF-06840003 is a highly selective orally bioavailable IDO-1 inhibitor with IC50s of 0.41 μM, 0.59 μM, and 1.5 μM for hIDO-1, dIDO-1, and mIDO-1, respectively. 了解更多 -
Dabigatran ethyl ester hydrochloride
Catalog No. A20805 NQO2 inhibitorDabigatran ethyl ester hydrochloride is a potent inhibitor of ribosyldihydronicotinamide dehydrogenase (NQO2) with an IC50 value of 0.8 μM and a thrombin inhibitor. 了解更多 -
amyloid P-IN-1
Catalog No. A20787 amyloid P-IN-1 is used in the research of diseases or disorders wherein depletion of serum amyloid P component (SAP), including amyloidosis, Alzheimer's disease, type 2 diabetes mellitus and osteoarthritis. 了解更多 -
trans-ACPD
Catalog No. A20779 metabotropic receptor agonisttrans-ACPD, a metabotropic receptor agonist, produces calcium mobilization and an inward current in cultured cerebellar Purkinje neurons. 了解更多 -
Solabegron
Catalog No. A20778 β3-adrenergic receptor agonistSolabegron (GW 427353) is a selective β3-adrenergic receptor agonist, stimulating cAMP accumulation in Chinese hamster ovary cells expressing the human β3-AR, with an EC50 value of 22 nM. 了解更多
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