“ab fubinaca”的搜索结果

产品 201 到 250 共 1548个

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  1. Thyroxine sulfate

    Catalog No. A20537
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    Thyroxine sulfate is a thyroid hormone metabolite. 了解更多
  2. Succinic anhydride

    Catalog No. A20536
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    nonclaevable ADC linker
    Succinic anhydride is a cyclic anhydride and a nonclaevable ADC linker extracted from patent WO2009064913A1. Succinic anhydride can react with compound 4 of the patent to link the prodrug to an amine or hydroxy 1 group of a targeting polypeptide. 了解更多
  3. NCB-0846

    Catalog No. A20535
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    TNIK inhibitor
    NCB-0846 is an orally available TNIK inhibitor with an IC50 of 21?nM. 了解更多
  4. Nicotinamide N-oxide

    Catalog No. A20532
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    CXCR2 receptor antagonist
    Nicotinamide N-oxide, an in vivo nicotinamide metabolite, is a potent, and selective antagonist of the CXCR2 receptor. 了解更多
  5. MLi-2

    Catalog No. A20530
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    brain penetrant LRRK2 inhibitor
    MLi-2 is a potent, highly selective, orally available, brain penetrant inhibitor of LRRK2 with an IC50 of 0.76 nM. 了解更多
  6. GS-444217

    Catalog No. A20517
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    ASK1 inhibitor
    GS-444217 is a potent, orally available and selective ATP-competitive inhibitor of apoptosis signal-regulating kinase 1 (ASK1) with an IC50 of 2.87 nM. 了解更多
  7. Antihistamine-1

    Catalog No. A20515
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    Antihistamine-1 is a H1-antihistamine (Ki=6.9 nM) with acceptable blood-brain barrier penetration and also an inhibitor of CYP2D6 and hERG channel with IC50s of 5.4 and 0.8 μM, respectively. 了解更多
  8. 4-Acetamidobutanoic acid

    Catalog No. A20514
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    4-Acetamidobutanoic acid (N-acetyl GABA) is a γ-aminobutyric acid (GABA) derivative. 了解更多
  9. CYC065

    Catalog No. A20512
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    CDK2/9 inhibitor
    CYC065 is a second-generation, orally available ATP-competitive inhibitor of CDK2/CDK9 kinases with IC50s of 5 and 26 nM, respectively. 了解更多
  10. Lodelaben

    Catalog No. A20510
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    human neutrophil elastase inhibitor
    Lodelaben is a human neutrophil elastase inhibitor with an IC50 and Ki of 0.5 and 1.5 μM, respectively. 了解更多
  11. KDM5-IN-1

    Catalog No. A20507
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    KDM5 inhibitor
    KDM5-IN-1 is a potent, selective and orally bioavailable KDM5 inhibitor with an IC50 of 15.1 nM. 了解更多
  12. L-DABA

    Catalog No. A20506
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    GABA transaminase inhibitor
    L-DABA (L-2,4-Diaminobutyric acid) is a week GABA transaminase inhibitor with an IC50 of larger than 500 μM; exhibits antitumor activity in vivo and in vitro. 了解更多
  13. ER-000444793

    Catalog No. A20505
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    mPTP opening inhibitor
    ER-000444793 is a potent inhibitor of mitochondrial permeability transition pore (mPTP) opening. ER-000444793 inhibits mPTP with an IC50 of 2.8?μM. 了解更多
  14. Vanilpyruvic acid

    Catalog No. A20498
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    Vanilpyruvic acid is a catecholamine metabolite and precursor to vanillactic acid. 了解更多
  15. DC_C66

    Catalog No. A20497
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    CARM1 inhibitor
    DC_C66 is a cell-permeable, selective coactivator associated arginine methyltransferase 1 (CARM1) inhibitor with an IC50 of 1.8 μM. 了解更多
  16. MSOP

    Catalog No. A20495
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    group III mGluR antagonist
    MSOP is a selective group III metabotropic glutamate receptor antagonist with apparent KD of 51 μM for the L-AP4-sensitive presynaptic mGluR. 了解更多
  17. Diethyl phosphate

    Catalog No. A20494
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    Diethylphosphate (DEP) is product of metabolism and of environmental degradation of a commonly used insecticide Chlorpyrifos. 了解更多
  18. Oxaquin

    Catalog No. A20486
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    Oxaquin (MCB-3837) is a water-soluble, injectable prodrug that is rapidly converted to the active sub-stance MCB3681 in vivo following intravenous (i.v.) administration, active against Gram-positive bacterial species. Oxaquin (MCB-3837) itself has no antimicrobial effects. 了解更多
  19. Fumarate hydratase-IN-1

    Catalog No. A20471
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    fumarate hydratase inhibitor
    Fumarate hydratase-IN-1 (compound 2) is a cell-permeable fumarate hydratase inhibitor. Fumarate hydratase-IN-1 has antiproliferative activity against several cancer cell lines with a mean IC50 of 2.2 μM. 了解更多
  20. Paquinimod

    Catalog No. A20468
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    S100A9 inhibitor
    Paquinimod is a S100A9 inhibitor, which prevents S100A9 binding to TLR-4. 了解更多
  21. BRCA1-IN-2

    Catalog No. A20464
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    PPI inhibitor
    BRCA1-IN-2 (compound 15) is a cell-permeable protein-protein interaction (PPI) inhibitor for BRCA1 with an IC50 of 0.31 μM and a Kd of 0.3 μM, which shows antitumor activities via the disruption of BRCA1 (BRCT)2/protein interactions. 了解更多
  22. TAK-659

    Catalog No. A20450
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    SYK/FLT3 inhibitor
    TAK-659 is a highly potent, selective, reversible and orally available dual inhibitor of spleen tyrosine kinase (SYK) and fms related tyrosine kinase 3 (FLT3), with an IC50 of 3.2 nM and 4.6 nM for SYK and FLT3, respectively. 了解更多
  23. Ralfinamide

    Catalog No. A20446
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    Na+ blocker
    Ralfinamide (FCE-26742A) is an orally available Na+ blocker derived from α-aminoamide, with function of suppressing pain. 了解更多
  24. KDM5A-IN-1

    Catalog No. A20436
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    KDM5 inhibitor
    KDM5A-IN-1 is a potent, orally bioavailable pan-histone lysine demethylases 5 (KDM5) inhibitor with IC50s of 45 nM, 56 nM and 55 nM for KDM5A, KDM5B and KDM5C, respectively, and with an EC50 value of 960 nM for PC9 H3K4Me3. 了解更多
  25. Urolithin A

    Catalog No. A20426
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    Urolithin A, a gut-microbial metabolite of ellagic acid, exerts anti-inflammatory, antiproliferative, and antioxidant properties. Urolithin A induces autophagy and apoptosis, suppresses cell cycle progression, and inhibits DNA synthesis. 了解更多
  26. LDN-0088050

    Catalog No. A20415
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    FABP4 inhibitor
    LDN 0088050 is selectivity adipocyte fatty acid binding protein (AFABP, FABP4) inhibitor with Ki values of 0.29 and 1.3 μM for FABP4 and FABP3, respectively. LDN 0088050 binds to FABP4 with a Kd of 2.05 μM. 了解更多
  27. JZP-430

    Catalog No. A20413
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    ABHD6 inhibitor
    JZP-430 is a potent, highly selective, irreversible inhibitor of α/β-hydrolase domain 6 (ABHD6) with an IC50 of 44 nM, exhibits ~230-fold selectivity over fatty acid amide hydrolase (FAAH) and lysosomal acid lipase (LAL). 了解更多
  28. Tomivosertib

    Catalog No. A20407
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    MNK1/MNK2 inhibitor
    Tomivosertib (eFT508) is a potent, highly selective, and orally bioavailable MNK1 and MNK2 inhibitor, with IC50s of 1-2 nM against both isoforms. 了解更多
  29. Acelarin

    Catalog No. A20397
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    Acelarin (NUC-1031) is a ProTide transformation and enhancement of the widely-used nucleoside analogue, gemcitabine. 了解更多
  30. Biotin-VAD-FMK

    Catalog No. A20384
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    caspase inhibitor
    Biotin-VAD-FMK is a cell permeable, irreversible biotin-labeled caspase inhibitor, used to identify active caspases in cell lysates. 了解更多
  31. (±)-Zanubrutinib

    Catalog No. A20381
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    Btk inhibitor
    (±)-Zanubrutinib is a potent, selective and orally available Bruton's tyrosine kinase (Btk) inhibitor. 了解更多
  32. BTTAA

    Catalog No. A20374
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    BTTAA is a Cu(I)-stabilizing ligand, whch performs potently with ubiquitin Glu18AzF. 了解更多
  33. RMI 10874

    Catalog No. A20370
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    RMI 10874 is a tilorone analogue. Tilorone is a small-molecule, orally bioavailable antiviral agent. RMI 10874 completely abolishes lung colonization of an H-2 negative (GR9.B9) MCA-induced fibrosarcoma clone. 了解更多
  34. 6-Hydroxybentazon

    Catalog No. A20362
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    6-Hydroxybentazon is a phase I metabolite of bentazone, and bentazone is a chemical for use in herbicides. 了解更多
  35. Trimethoprim 3-oxide

    Catalog No. A20361
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    Trimethoprim 3-oxide (Trimethoprim 3-N-oxide) is the primary metabolite of trimethoprim. 了解更多
  36. BP-1-102

    Catalog No. A20347
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    Stat3 inhibitor
    BP-1-102 is an orally available, small-molecule inhibitor of transcription factor Stat3, with an IC50 of 6.8 μM. 了解更多
  37. Paprotrain

    Catalog No. A20346
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    MKLP-2 inhibitor
    Paprotrain is a cell-permeable inhibitor of the kinesin MKLP-2, inhibits the ATPase activity of MKLP-2 with an IC50 of 1.35 μM and a Ki of 3.36 μM and shows a moderate inhibition activity on DYRK1A with an IC50 of 5.5 μM. 了解更多
  38. GZD856

    Catalog No. A20345
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    PDGFRα/β inhibitor
    GZD856 is a novel and orally bioavailable PDGFRα/β inhibitor with IC50s of 68.6 and 136.6 nM, respectively. 了解更多
  39. Emtricitabine S-oxide

    Catalog No. A20337
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    nucleoside reverse transcriptase inhibitor
    Emtricitabine S-oxide (Emtricitabine sulfoxide) is a major degradation product of Emtricitabine. Emtricitabine is a potent nucleoside reverse transcriptase inhibitor used for the treatment of HIV infection. 了解更多
  40. CEP-40783

    Catalog No. A20331
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    AXL/c-Met inhibitor
    CEP-40783 is a potent, selective and orally available inhibitor of AXL and c-Met with IC50 values of 7 nM and 12 nM, respectively. 了解更多
  41. Nucleocidin

    Catalog No. A20329
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    Nucleocidin is an antitrypanosomal antibiotic, inhibiting the transfer of labeled amino acid from S-RNA to protein. 了解更多
  42. ML230

    Catalog No. A20298
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    ABCG2 inhibitor
    ML230 (CID44640177; SID 88095709) is a selective inhibitor of ATP-binding cassette (ABC) transporter ABCG2, and 36-fold selective for ABCG2 over ABCB1 with EC50s values of 0.13 μM and 4.65 μM, respectively. 了解更多
  43. Tazanolast

    Catalog No. A20296
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    Tazanolast is a selective mast-cell-stabilizing drug, on ozone-induced airway hyperresponsiveness in guinea pigs. 了解更多
  44. GNE 5729

    Catalog No. A20295
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    NMDAR modulator
    GNE 5729 is a brain permeable positive allosteric modulator of NMDAR, with an EC50 of 37 nM for GluN2A, 4.7 and 9.5 μM for GluN2C and GluN2D, respectively. 了解更多
  45. Dexanabinol

    Catalog No. A20290
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    Dexanabinol exhibits not only the antioxidant and neuroprotective activities in brain but also anti-inflammatory activity by inhibiting NF-κB and decreasing cytokines such as TNFα and interleukin-6, which could ensure the integrity of BBB and reduce cell apoptosis and death. 了解更多
  46. Abaperidone

    Catalog No. A20286
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    5-HT2A/dopamine D2 antagonist
    Abaperidone is a potent antagonist of 5-HT2A?receptor and dopamine D2 receptor with IC50s of 6.2 and 17 nM. 了解更多
  47. KY1220

    Catalog No. A20284
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    KY1220 is a compound that destabilizes both β-catenin and Ras, via targeting the Wnt/β-catenin pathway; with an IC50 of 2.1 μM in HEK293 reporter cells. 了解更多
  48. HS79

    Catalog No. A20281
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    FASN inhibitor
    HS-79 is an enantiomer of Fasnall, which is a selective fatty acid synthase (FASN) inhibitor. HS-79 is able to inhibit the incorporation of tritiated acetate into lipids with an IC50 of 1.57 μM. 了解更多
  49. Nebicapone

    Catalog No. A20279
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    COMT inhibitor
    Nebicapone (BIA 3-202), a reversible catechol-O-methyltransferase (COMT) inhibitor, is mainly metabolized by glucuronidation. 了解更多
  50. Zabofloxacin

    Catalog No. A20246
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    antibacterial candidate for clinical trials
    Zabofloxacin (DW-224a Free base) is a novel fluoronaphthyridone quinolone with a 7-pyrrolidone substituent that is considered a potent antibacterial candidate for clinical trials. 了解更多

产品 201 到 250 共 1548个

每页
页面:
  1. 3
  2. 4
  3. 5
  4. 6
  5. 7

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