CRM1

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  1. KPT185

    Catalog No. A12975
    CRM1 Inhibitor
    KPT185 is a selective CRM1 inhibitor. KPT-185 significantly inhibits leukemia cell proliferation with IC50 ranging from 100 nM to 500 nM, and induces cell-cycle arrest and apoptosis of AML cell lines and primary AML blasts. 了解更多
  2. KPT-330

    Catalog No. A12582
    CRM1 inhibitor
    KPT-330 inhibitor of CRM1 (XPO1)-mediated nuclear export has selective anti-leukaemic activity in preclinical models of T-cell acute lymphoblastic leukaemia and acute myeloid leukaemia. 了解更多

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