Product Data Sheet
BAY-184
Catalog No. A29182
BAY-184 is a selective inhibitor of KAT6A and KAT6B, demonstrating effective oral bioavailability. With IC50 values of 71 nM for KAT6A and 83 nM for KAT6B, BAY-184 significantly inhibits KAT6 activity. This compound is capable of diminishing estrogen receptor alpha (ERα) transcriptional activity and has shown efficacy in reducing the proliferation of various breast cancer subtypes, ultimately leading to inhibition of tumor growth.
Chemical Information
| Catalog Num | A29182 |
|---|---|
| M. Wt | 420.48 |
| Formula | C23H20N2O4S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2520347-03-7 |
| Synonyms | |
| SMILES | O=C(C1=CC2=C(C=C(N(C)C)C=C2)O1)NS(=O)(C3=C(C4=CC=CC=C4)C=CC=C3)=O |
| Storage |
Biological Activity
| Discription | BAY-184 is a selective inhibitor of KAT6A and KAT6B, demonstrating effective oral bioavailability. With IC50 values of 71 nM for KAT6A and 83 nM for KAT6B, BAY-184 significantly inhibits KAT6 activity. This compound is capable of diminishing estrogen receptor alpha (ERα) transcriptional activity and has shown efficacy in reducing the proliferation of various breast cancer subtypes, ultimately leading to inhibition of tumor growth. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
