Product Data Sheet
Cladribine-15N
Catalog No. A33044
Cladribine-15N is a nitrogen-15 labeled analog of Cladribine (2-Chloro-2′-deoxyadenosine), which acts as an inhibitor of adenosine deaminase. This compound plays a crucial role in inhibiting DNA synthesis, thereby preventing the repair of damaged DNA and influencing DNA methylation processes. It exhibits significant anti-lymphoma activity and is applicable in research involving various hematologic malignancies and multiple sclerosis. The stable isotope labeling allows for advanced analytical techniques in biological studies.
Chemical Information
| Catalog Num | A33044 |
|---|---|
| M. Wt | 286.68 |
| Formula | C10H12ClN415NO3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1360874-38-9 |
| Synonyms | 2-Chloro-2′-deoxyadenosine-15N; Cldado-15N; 2Cda-15N |
| SMILES | OC[C@H]1[C@H](O)C[C@@H](N2C=NC3=C2N=C(Cl)N=C3[15NH2])O1 |
| Storage |
Biological Activity
| Discription | Cladribine-15N is a nitrogen-15 labeled analog of Cladribine (2-Chloro-2′-deoxyadenosine), which acts as an inhibitor of adenosine deaminase. This compound plays a crucial role in inhibiting DNA synthesis, thereby preventing the repair of damaged DNA and influencing DNA methylation processes. It exhibits significant anti-lymphoma activity and is applicable in research involving various hematologic malignancies and multiple sclerosis. The stable isotope labeling allows for advanced analytical techniques in biological studies. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
