Product Data Sheet
EHT 5372
Catalog No. A35065
EHT 5372 is a potent and selective inhibitor of the DYRK family of kinases, demonstrating IC50 values of 0.22 nM for DYRK1A and 0.28 nM for DYRK1B. It exhibits notable inhibition against other members of the DYRK family and related kinases, making it a valuable tool for investigating the role of DYRKs in cellular signaling pathways. EHT 5372 is primarily utilized in research applications focused on neurodegenerative diseases and cancer, facilitating studies on cell proliferation, differentiation, and apoptosis.
Chemical Information
| Catalog Num | A35065 |
|---|---|
| M. Wt | 404.27 |
| Formula | C17H11Cl2N5OS |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1425945-63-6 |
| Synonyms | |
| SMILES | N=C(C(S1)=NC2=C1C3=C(NC4=CC=C(Cl)C=C4Cl)N=CN=C3C=C2)OC |
| Storage |
Biological Activity
| Discription | EHT 5372 is a potent and selective inhibitor of the DYRK family of kinases, demonstrating IC50 values of 0.22 nM for DYRK1A and 0.28 nM for DYRK1B. It exhibits notable inhibition against other members of the DYRK family and related kinases, making it a valuable tool for investigating the role of DYRKs in cellular signaling pathways. EHT 5372 is primarily utilized in research applications focused on neurodegenerative diseases and cancer, facilitating studies on cell proliferation, differentiation, and apoptosis. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
