Product Data Sheet
EMD 66684
Catalog No. A59021
EMD 66684 is a potent antagonist of the Angiotensin II Type 1 (AT1) receptor, exhibiting a binding affinity with an IC50 value of 0.7 nM. This compound is known for its biological activity in blocking AT1 receptor-mediated signaling pathways, making it a valuable tool for studying cardiovascular and renal physiology. Additionally, EMD 66684 demonstrates anti-ischemic cytoprotective properties, supporting its application in research focused on ischemic conditions and related therapies.
Chemical Information
| Catalog Num | A59021 |
|---|---|
| M. Wt | 547.05 |
| Formula | C28H31ClN8O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1216884-39-7 |
| Synonyms | |
| SMILES | O=C1C2=C(C=CN1CC(N(C)C)=O)N=C(CCCC)N2CC3=CC=C(C4=C(C5=NN=NN5)C=CC=C4)C=C3.Cl |
| Storage |
Biological Activity
| Discription | EMD 66684 is a potent antagonist of the Angiotensin II Type 1 (AT1) receptor, exhibiting a binding affinity with an IC50 value of 0.7 nM. This compound is known for its biological activity in blocking AT1 receptor-mediated signaling pathways, making it a valuable tool for studying cardiovascular and renal physiology. Additionally, EMD 66684 demonstrates anti-ischemic cytoprotective properties, supporting its application in research focused on ischemic conditions and related therapies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
