AC-42
Catalog No. A61447
AC-42 is a selective allosteric agonist for the M1 muscarinic receptor, exhibiting potent activity with EC50 values of 805 nM for the human wild-type and 220 nM for the Y381A mutant receptor. This compound enhances inositol phosphate (IP) accumulation and calcium mobilization in CHO cells, making it a valuable tool for studying M1 receptor signaling pathways. Its unique mechanism of action facilitates research into neuropharmacology and cognitive function modulation.
Chemical Information
| Catalog Num | A61447 |
|---|---|
| M. Wt | 301.47 |
| Formula | C20H31NO |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 244291-63-2 |
| Synonyms | |
| SMILES | O=C(CCCN1CCC(CC1)CCCC)C2=CC=CC=C2C |
| Storage |
Biological Activity
| Discription | AC-42 is a selective allosteric agonist for the M1 muscarinic receptor, exhibiting potent activity with EC50 values of 805 nM for the human wild-type and 220 nM for the Y381A mutant receptor. This compound enhances inositol phosphate (IP) accumulation and calcium mobilization in CHO cells, making it a valuable tool for studying M1 receptor signaling pathways. Its unique mechanism of action facilitates research into neuropharmacology and cognitive function modulation. |
|---|
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
