Product Data Sheet
AFP464
Catalog No. B21896
AFP464 is a prodrug of Aminoflavone and an agonist of the aryl hydrocarbon receptor (AhR). It exhibits significant biological activity by downregulating α6-integrin expression, inhibiting breast tumor growth, and reducing the population of tumor-initiating cells. Additionally, AFP464 disrupts mammosphere structure, induces mucin lake cluster formation, triggers DNA damage, and demonstrates antiproliferative effects. This compound is suitable for research applications focused on breast cancer.
Chemical Information
| Catalog Num | B21896 |
|---|---|
| M. Wt | 640.65 |
| Formula | C24H31F3N4O9S2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 468719-53-1 |
| Synonyms | NSC710464 |
| SMILES | CS(=O)(O)=O.FC1=C2C(C(C=C(C3=CC(F)=C(C=C3)NC([C@@H](N)CCCCN)=O)O2)=O)=C(C(F)=C1C)N.CS(=O)(O)=O |
| Storage |
Biological Activity
| Discription | AFP464 is a prodrug of Aminoflavone and an agonist of the aryl hydrocarbon receptor (AhR). It exhibits significant biological activity by downregulating α6-integrin expression, inhibiting breast tumor growth, and reducing the population of tumor-initiating cells. Additionally, AFP464 disrupts mammosphere structure, induces mucin lake cluster formation, triggers DNA damage, and demonstrates antiproliferative effects. This compound is suitable for research applications focused on breast cancer. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
