Methotrexate (Abitrexate)

Catalog No. A10021

Methotrexate (Abitrexate)是一种抑制胸苷酸合成酶和从头嘌呤合成的细胞毒剂。

Technical details

Catalog Num	A10021
M. Wt	454.44
Formula	C20H22N8O5
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	CAS: 59-05-2
Synonyms	MTX, amethopterin, Abitrexate, Rheumatrex, Trexall
SMILES	CN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)O)C(=O)O

Biological Activity

Methotrexate (Abitrexate)是一种抑制胸苷酸合成酶和从头嘌呤合成的细胞毒剂。

Solubility *

In vitro (25°C)	DMSO	Warmed: 89 mg/mL (195.84 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	2% DMSO+30% PEG 300+5% Tween 80+ddH2O	4 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.01 mL	110.03 mL	220.05 mL
0.5 mM	4.4 mL	22.01 mL	44.01 mL
1 mM	2.2 mL	11 mL	22.01 mL
5 mM	0.44 mL	2.2 mL	4.4 mL

*The above data is based on the productmolecular weight 454.44. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Adooq Bioscience

Methotrexate (Abitrexate)

Technical details

Biological Activity

Solubility *

Preparing Stock Solutions